-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan109/preeclampsia-screening-april-2017
August 14, 2014 - guide a systematic review of the evidence by researchers at an Evidence-based Practice Center. … How effectively do screening tests (e.g., blood pressure, proteinuria) identify women with preeclampsia … , postmarketing surveillance, and case reports
Screening effectiveness (KQ 4): Editorial, narrative … review, commentary, postmarketing surveillance, and case reports
Harms (KQs 3, 5) : Editorial, narrative … review, commentary, postmarketing surveillance, and case reports
Publication dates
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/statin-use-in-adults-preventive-medication
November 05, 2020 - 1. a. … How do the benefits and harms of statin treatment vary according to its intensity? … How do patient preferences regarding use of statins for primary prevention vary at different cardiovascular … and case-control studies on harms of statins vs. no statin for primary prevention
Case series, case … reports; poor-quality studies
Abbreviations: CHD=coronary heart disease; CVA=cerebrovascular
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cardiovascular-diseas/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
October 07, 2013 - The figure illustrates how regular aspirin use in patients without known cardiovascular disease may result … in a decrease in myocardial infarction, ischemic stroke, and mortality related to all causes and cardiovascular … Do these cardiovascular risk prediction tools vary by subgroup? … clinical trials; large prospective cohort studies
KQ 1: Observational studies (cohort, case control, case … studies, or case series)
KQ 2: Case-control, case studies, or case series
Setting
Outpatient
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-screening
May 06, 2021 - How do racism, social inequalities, unequal access to high-quality healthcare, and other factors contribute … How do new findings, analyses, or longer-term followup from foundational effectiveness trials of mammography … What risk assessment tools are available for use in average-risk screening populations and how well do … How do the personal preferences of specific populations (including those that are under-represented in … The USPSTF added a note to the Research Plan to explain that the evidence review would be accompanied
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/syphilis-infection-pregnant-persons
December 01, 2022 - How frequently do pregnant persons who initially test negative for syphilis with serologic screening … either later test positive for syphilis, give birth to a neonate with congenital syphilis, or have a … Do these associations vary by populations of interest (demographic characteristics or risk factors)? … systematic reviews and meta-analyses (of included study designs)
Narrative reviews, editorials, and case … reports
Publication Language
English
Non-English studies
Study Quality
Good- or fair-quality
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-pregnant-persons
March 02, 2023 - To better understand the need for retesting during pregnancy, the USPSTF will review how frequently do … a neonate with congenital syphilis, or have a miscarriage or stillbirth attributed to syphilis? … Do these associations vary by populations of interest (demographic characteristics or risk factors)? … systematic reviews and meta-analyses (of included study designs)
Narrative reviews, editorials, and case … reports
Publication Language
English
Non-English studies
Quality
Good- or fair-quality
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-in-pregnancy-screening
March 02, 2023 - To better understand the need for retesting during pregnancy, the USPSTF will review how frequently do … a neonate with congenital syphilis, or have a miscarriage or stillbirth attributed to syphilis? … Do these associations vary by populations of interest (demographic characteristics or risk factors)? … systematic reviews and meta-analyses (of included study designs)
Narrative reviews, editorials, and case … reports
Publication Language
English
Non-English studies
Quality
Good- or fair-quality
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cervical-cancer-screening-adults-adolescents
October 28, 2021 - Do the comparative harms vary by population (e.g., by age, gender, race and ethnicity, or HPV immunization … How do different levels of racism and other factors contribute to inequities in cervical cancer incidence … studies
Participation trials (for adherence only)
KQs 1, 3:
Non-nested case-control studies
Case … reports
Case series
Narrative reviews
Editorials
KQ 2:
Diagnostic test accuracy studies … commission a decision model to accompany this evidence review.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - What is the evidence to determine screening intervals, and how do these intervals vary by baseline or … How do various fracture risk assessment tools use race and ethnicity in fracture risk calculations? … median or mean of 80% of the time specified by the FRA (e.g., at least 8 years for a tool designed to … For FRAs or ORAs that do not specify a prediction interval, a minimum of 3 years of observed incidence … reports; case-control studies; conference abstracts, posters, or proceedings without data or information
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hypertensive-disorders-pregnancy-screening
September 02, 2021 - How effective are different screening programs used to identify hypertensive disorders of pregnancy … How do racism and social inequalities contribute to existing inequities in morbidity and mortality from … How are risk assessment and risk prediction tools being used in clinical practice to inform screening … over time or between settings, population cohort studies, nested case-control studies)
Studies that do … Publication Dates
References from the previous USPSTF review, and eligible studies identified through a
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
May 14, 2015 - The figure illustrates how behavioral counseling to improve diet, increase physical activity, and reduce … Additionally, the figure illustrates how counseling to promote a healthful diet, increased physical activity … Do primary care behavioral counseling interventions to improve diet, increase physical activity, and/ … Do primary care behavioral counseling interventions to improve diet, increase physical activity, and/ … reports
Publication date
Trials whose primary results were published from 1990 to present
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/child-maltreatment-primary-care-interventions-november-2018
August 18, 2016 - Do primary care–feasible or referable interventions to prevent child maltreatment reduce exposure … parent or caregiver against a child
Physical (e.g., failure to thrive), emotional, dental/medical ( … studies
KQ 2: Case series or case studies
Timing
Any timing
None
Languages
Full … Information on how children, adolescents, or their caregivers are selected for interventions (former … Preventing Child Maltreatment: A Guide to Taking Action and Generating Evidence.
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
February 09, 2023 - How well do interventions reduce exposure to IPV, physical or mental morbidity, or mortality among screen-detected … How well do interventions reduce exposure to abuse and neglect, physical or mental morbidity, or mortality … If so, how well do they perform in distinguishing between those who are at high vs. low risk of abuse … screening; studies of other interventions that do not include a health service component (e.g., effectiveness … screening; studies of other interventions that do not include a health service component (e.g., effectiveness
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan6/high-blood-pressure-in-adults-screening-monitoring-october-2015
September 15, 2013 - How well do home and ambulatory blood pressure monitoring methods predict cardiovascular events compared … are designed to assess devices versus blood pressure measurement standards
KQ 3a: Studies that do … studies
KQ 5: RCTs, CCTs, cohort studies
Before-after studies, time series, case series, case … reports; studies enrolling treated hypertension patients with less than a 2-week washout period … in response to a variety of comments.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
July 17, 2014 - How do the harms e of routine breast cancer screening differ by screening strategy d ? … How do these performance characteristics differ by age and risk factor b ? … How do these performance characteristics differ by age and risk factor b ? … How do women weigh the harms and benefits of screening mammography and how do they use this information … Case reports, case series; studies outside of search dates unless updates of previous trials.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening
October 29, 2015 - For each primary screening strategy, how does the rescreening interval relate to future cancer incidence … clinical trials
Cohort studies, including patient registries
KQs 1, 2:
Case-control studies
Case … reports
Case series
Narrative reviews
Editorials
Setting
KQs 1, 2: Primary care ( … The model will also investigate how individual-level factors—adherence to recommended screening, surveillance … How to evaluate emerging technologies in cervical cancer screening?
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan29/diet-behavioral-counseling-primary-care-adults-2003
February 03, 2014 - The final Research Plan is used to guide a systematic review of the evidence by researchers at … The figure illustrates how behavioral counseling interventions for healthy diet and/or physical activity … The figure also depicts how these interventions may influence intermediate health outcomes associated … case-control studies
KQs 1–3: Any observational studies
KQ 4: Ecological studies, case-series, case … reports
Publication Date
Trials published from 1990 to present
Trials whose primary results
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan18/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
May 15, 2013 - The figure illustrates how interventions to reduce the illicit or nonmedical use of drugs may improve … the health care system by participant
How delivered: To individuals or in small groups (15 or less … studies
Before-after studies
Cross-sectional studies
Editorials, commentaries, case … studies, case series
Study geography
Developed countries; rated “Very High” according … A few other minor changes were made to clarify inclusion criteria and outcomes.
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/vision-screening-children-ages-6-months-5-years
April 24, 2025 - How do rates of completion of eye examinations and obtaining appropriate treatment for amblyopia, its … trials; controlled cohort studies; case-control studies
KQ 4: Randomized, controlled trials
Case … reports, case series, systematic reviews, and all other study designs not listed as eligible; systematic … containing potentially relevant studies will be hand-searched for eligible articles
KQ 2: Studies that do … not attempt to perform the reference standard in all participants or a random sample of participants
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
April 20, 2023 - How well do interventions reduce exposure to IPV, physical or mental morbidity, or mortality among screen-detected … How well do interventions reduce exposure to caregiver abuse and neglect, physical or mental morbidity … If so, how well do they perform in distinguishing between those who are at high vs. low risk of abuse … screening; studies of other interventions that do not include a health service component (e.g., effectiveness … screening; studies of other interventions that do not include a health service component (e.g., effectiveness