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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - This therapy is
sometimes referred to as
“chemoprevention” in the literature,
although this is not a … and examine how benefits and harms vary by
age, breast cancer risk status, and other factors. … The
term “medications to reduce risk” is a better
representation of the intervention and therefore, all … How do outcomes for tamoxifen
citrate, raloxifene, and tibolone when used for
primary prevention of breast … estrogen receptor modulators
(
How
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effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - The analysis highlights both
theoretical and operational issues, including how to (1) choose
appropriate … How-
ever, a priori, we do not hypothesize that seizures or throm-
bocytopenia are biologically plausible … Evaluation Using Historical Data
To illustrate how the system may perform, we applied
the technique … to identify a true signal. … To do this, we will use
secondary definitions of exposed and unexposed groups,
evaluate temporal clustering
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Therefore, we do not compare the
amount and quality of evidence to the
treatment of other rare but … that the instrument most often used – CHAQ – does not do a good
job of capturing how kids are really … As a clinician, I want to know how best to treat an
individual patient with a defined subtype of JIA … Points out how
little information is available to help with informed decision making. … phenotype, with
some suggestions on how to tackle this.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
March 01, 2021 - (2) How
do TMTs affect the sensitivity and yield of searches? … (2) How do TMTs affect the sensitivity and yield of searches? … In order to understand how TMT librarians were using the tools,
we asked for a brief description of … Another limitation has to do with variations in how librarians operationalized time recording
and search … 'Clustering'
documents automatically to support scoping
reviews of research: a case study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - There were too few studies to
support any conclusions about how mortality differed
between the medications … There were
too few studies to support any conclusions about how
cardiovascular morbidity or mortality … No cases of
macular edema were identified in the studies reviewed;
however, case reports were excluded … Data were too sparse to
draw conclusions about how the incidence of edema
may differ between other oral … Cardiovascular Low to very low There were too few studies to support any conclusions about how
morbidity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - In general, the figure illustrates how newer medications work in men with
LUTS/BPH to improve LUTS, … Do not
use justification as
“because the
AE/TOO/TEP/Peer
reviewer told us to” but
explain what the … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report … They have not reviewed the report, except as
given the opportunity to do so through the peer or public … (addresses or autobiography or bibliography or biography or case
reports or clinical conference or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
November 27, 2012 - none of these efforts will make a meaningful difference if we do
not broaden screening to detect many … An essential point will be for this review to help us determine in whom and how frequently do
patients … I have to do some sleuthing to
find it. … • At-risk people do not know that they are at risk or how to prevent becoming infected. … • Many health-care providers do not screen people for risk factors or do not know how to
manage infected
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
February 03, 2025 - How do these associations vary by intensity (including exclusivity), duration, and
mode of feeding, … developed countries if the reported data allow us to do
so. … They do not review the report, except as given the opportunity to do so
through the peer or public review … Technical Experts do not do
analysis of any kind; neither do they contribute to the writing of the report … They do not review
the report, except as given the opportunity to do so through the peer or public review
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - Key questions and summary of results from CER
Key Question Summary Results
1) How do different
methods … How do different
methods for detection of
toxigenic CD compare in their
sensitivity, specificity, … How do different methods for detection of toxigenic Clostridium difficile to assist with
diagnosis … How do prevention and treatment of CDI affect resistance of other pathogens?
4. … How do different
methods for detection of
toxigenic CD compare in their
sensitivity, specificity,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_technical-brief.pdf
January 01, 2020 - What medical claims about effectiveness have been made, and how do they compare
to what is available … The out-of-pocket costs may affect whether,
where, and how often a consumer uses a whole-body vibration … What information do clinicians and patients need to know to make informed decisions
about whole-body … What information do clinicians and patients need to know when to use alternative
therapeutic options … (English language and humans and yr="2000 -Current") (127)
19 limit 18 to (case reports or editorial
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
November 28, 2012 - Studies will be excluded for KQs 1–3 if they:
Are non-English language
Are case reports that … do not report on a severe adverse event
Are editorials or literature reviews
Have treatment dates … How should meta-regression analyses be undertaken
and interpreted? … How to formulate research
recommendations. BMJ 2006 October 14, 2006;333(7572):804-6. … Technical Experts do not do
analysis of any kind nor contribute to the writing of the report and have
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
September 15, 2014 - The
differentiation of obstruction from DU is often paramount in
deciding if and how to treat a patient … I do not think
the study design allows that conclusion. … We have revised the text to clarify the findings of this study and
added text to describe how PVR was … I do not think that the conclusions of the manuscript as
constructed and be used to inform policy and … A
presentation describing how the key questions were selected will
help to fend off criticisms for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
June 12, 2014 - Finally, in response to a
comment about how previously negative testing affects test accuracy, we added … Question 3: How do accuracy, (sensitivity, specificity, LR+, LR-, summary ROCs) and
outcomes differ … Case reports will be excluded for all KQs. … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report … They have not reviewed the report, except as
given the opportunity to do so through the peer or public
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - to locate a testis with imaging should preclude the need for
surgery as it indicates a lack of a potentially … study
design and other criteria)
Admissible designs
All study designs will be considered, except case … reports
For KQ1 and KQ2, single-arm studies may be included
For KQ3 and KQ4, studies must use … Technical Experts do not do
analysis of any kind nor contribute to the writing of the report and have … not reviewed the report,
except as given the opportunity to do so through the public review mechanism
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
December 01, 2011 - reports, or press releases? … Their perspectives include their vision
and plans for how they intend to carry out diffusion of a technology … News, information on issues &
advocacy efforts, case studies on various
technologies AdvaMed SmartBrief … How convinced are you about its potential to improve
patient outcomes? … do you think [Horizon Scanning topic] has to disrupt how patients are managed and how
clinicians and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - is appropriate is to define how the test will be used. … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we … Specific instructions on how to do so are outside the scope of this training module but can be found … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - is appropriate is to define how the test will be used. … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we … Specific instructions on how to do so are outside the scope of this training module but can be found … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - This section of the Methods Guide discusses how to conduct a meta-analysis of test performance when there … This module focuses on how to conduct a meta-analysis with a “gold standard” reference. … Module 9 discusses how to conduct a meta-analysis when no gold standard reference exists. … This module focuses on how to conduct a meta-analysis for medical test performance when a gold standard … estimates of various studies do not vary widely or extensively
Can use a summary point to obtain summary
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - This section of the Methods Guide discusses how to conduct a meta-analysis of test performance when there … This module focuses on how to conduct a meta-analysis with a “gold standard” reference. … Module 9 discusses how to conduct a meta-analysis when no gold standard reference exists. … This module focuses on how to conduct a meta-analysis for medical test performance when a gold standard … estimates of various studies do not vary widely or extensively
Can use a summary point to obtain summary
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
September 01, 2012 - to change how delivery of care is routinely structrured. … This paper describes how a
systematic focus to improve processes and outcomes has positioned the program … DESIGN OF STUDY: Qualitative
interview case study. … DO. … It describes how a team of Macmillan and heart failure nurse
specialists attempted to address the problem