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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - them in a manner that makes it possible to do so. … reports. … Other nonrandomized designs, including spontaneous
case reports, may provide a useful source of information … case study of the risks and benefits of fish
consumption. … case study of alosetron in
irritable bowel syndrome.
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effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
May 27, 2016 - how that can lead to
adverse events. … How many seemed to
be effective? … Peer reviewer #5 Findings GQ1a They do not explain how patient centered care relates to safety
but … and ask us to take a leap of faith as to how to advance the
safety science. … We do hope that this brief can
provide a basis for researchers to build a
future research agenda that
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
February 01, 2023 - How do these associations vary by intensity (including exclusivity), duration, and
mode of feeding, … developed countries if the reported data allow us to do
so. … They do not review the report, except as given the opportunity to do so
through the peer or public review … Technical Experts do not do
analysis of any kind; neither do they contribute to the writing of the report … They do not review
the report, except as given the opportunity to do so through the peer or public review
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
August 01, 2012 - In trials of SMBP
monitoring, how do clinical, surrogate,
and intermediate outcomes (including
SMBP … How do different
devices for SMBP monitoring compare
with each other (specifically
semiautomatic or … How do different
metrics of aggregated SMBP readings predict risk for cardiovascular disease? … † 3
10 How do readings from clinic BP and SMBP compare with each other in their ability to
predict … , but do not mention how
to time measurements in relation to with food intake, exercise, coffee, alcohol
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
December 14, 2015 - You mention it as a
comparator, but do not mention how it is
used to diagnose appendicitis. … How do you interpret this question
in this situation? This is very
unclear to me. … How do you
define that? … Peer
Reviewer #1
Results For diagnostic imaging there is a problem
how to treat non-diagnostic scans … How do I
interpret that studies consist "almost
exclusively at moderate risk of bias
(primarily due
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
May 27, 2014 - How do we compare what is
‘effective’ with our usual care. … We do discuss
how alternative ways of classifying interventions
may lead to different conclusions ( … do they compare”, “how
much”, etc.:
“…how do transitional care interventions compare with usual
care … This is a big
deal! Again, returning to the problem of how do you get into the
study. … Do you have any data on how often such disagreement this
occurred?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
October 01, 2012 - 3
• How out of date is that portion of the CER? … October 2012 – A systematic
review of 5 studies (3 case
reports, 1 cohort, 1 RCT) of
spinal manipulation … because it was underpowered to do so. … reports, 1
cohort, 1 RCT) were retrieved
leading the authors to concluded
that there was insufficient … Do Not Know
underpowered to do so.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
May 17, 2018 - Has the Cochrane Collaboration made a similar
decision to not do quantitative meta-analysis when a body … ), but we argue that we do point the way
“forward” in how we can use the information gleaned
from 1 … I strongly urge you to reconsider the rigid decision to not
do quantitative meta-analyses when a body … , then it may be reasonable to not do a
quantitative meta-analysis. … The self-
management portion of the intervention has to do with
how the intervention was delivered.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - designs except single case reports
provided that studies reported on an intervention aimed
at individuals … the lives of individuals and how these
interventions generalize to real-world impact and
outcome. … Studies that do show
evidence of effectiveness in this area should collect
longer term data to describe … To some degree, this reflects a lack of understanding
and consensus about optimal outcomes and how to … Research is also necessary to understand how individuals’
expression of ASD symptoms and the severity
-
effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
March 29, 2016 - Peer Reviewer #1 Methods p. 7, line 30: how exactly do you plan on
updating the searches and until what … Peer Reviewer #1 Results KQ4, “Harms of Adjunctive Therapy,” there have
been a couple of case reports … Case
reports were an excluded article
category. … Unfortunately, the studies do not
report outcomes with enough
detail to do a subgroup analysis of … Peer Reviewer #6 Discussion The authors do a better job addressing how
fidaxomicin may be used given
-
effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
January 01, 2009 - It depends on the key questions being asked, but also on how far the data extractors are willing to go … Solutions:
Develop an evidence table guidance document—instructions on how to input data. … Seeing these patterns may enable us to see where the errors occurred, but we cannot actually do a lot … Why Do Such Problems Exist? … Why Do Such Problems Exist?
Reference:
Green BF, Hall JA.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - • How out of date is that portion of the CER? … less of a
signal to update than the former)? … How quickly do systematic reviews go
out of date? A survival analysis. … Do Not Know
Key Question 1: In children with JIA, does treatment with DMARDs, compared to conventional … Strength of Evidence: Insufficient
Key Question 4: How do the efficacy, effectiveness, safety, and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - • How out of date is that portion of the CER? … less of a
signal to update than the former)? … How quickly do systematic reviews go
out of date? A survival analysis. … Do Not Know
Key Question 1: In children with JIA, does treatment with DMARDs, compared to conventional … Strength of Evidence: Insufficient
Key Question 4: How do the efficacy, effectiveness, safety, and adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - Evidence consisted largely of case series and case reports. … Recognizing that observational studies, including case series, and case reports will
continue to be … Evidence consisted largely of case series and case reports. … Recognizing that observational studies, including case series, and case reports will
continue to be … study a web-
based stem cell
transplant support
system to see how
well it works
compared with
standard
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - solid fats with vegetable and seed oils.24,25 Identifying evidence to inform and substantiate how
recommendations … studies and n=1 samples
• Non-randomized studies that do not account
for any potential confounders … A Brief Review on How Pregnancy and Sex Hormones
Interfere with Taste and Food Intake. … Technical Experts do not do
analysis of any kind; neither do they contribute to the writing of the report … They do not review the
report, except as given the opportunity to do so through the peer or public review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure-surveillance-160412.pdf
May 29, 2025 - Geographic"variation"of"
hypertension"in"sub'saharan"Africa:"a"case"study"of"South"Africa." … "
" "
Key$Question$2:$
In"trials"of"SMBP"monitoring,"how"do"clinical,"surrogate,"and"intermediate"outcomes … (In$trials$of$SMBP$monitoring,$how$do$clinical,$surrogate,$and$intermediate$outcomes$(including$SMBP$ … (In$trials$of$SMBP$monitoring,$how$do$clinical,$surrogate,$and$intermediate$outcomes$(including$SMBP$ … $in$addition$to$
SMBP$with$Web$training.$
Key(Question(3:(How$do$different$devices$for$SMBP$monitoring
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
July 01, 2025 - • Where and How Do People Acquire the Prescription
Stimulants That They Are Misusing? … KQ2a: How Do These Consequences Vary Based on Type of
Stimulant and Patient Characteristics? … • Where and how do people acquire the prescription stimulants that they are
misusing? … reports
Setting United States Non-U.S. … pt] OR “case report”[tw] OR “case
reports”[tw] OR “case series”[tw] OR “comment on”[All Fields] OR congress
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Physicians may not always be sufficiently educated as to which diagnostic
test is best to use and how … The Key Questions
Question 1: How do different methods for detection of toxigenic C. difficile to … How do prevention and treatment of CDAD affect resistance of other pathogens? … We do not plan to review grey literature. … Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate
surfaces?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - When used with motor function classification,
this provides a description of how and where
a child … The goal is to present an
idea of how self-sufficient a child can be at
home, at school, and at outdoor … What do we really know about the transition to adult-centered
health care? … Technical Experts do not
do analysis of any kind nor contribute to the writing of the report and have … not reviewed the
report, except as given the opportunity to do so through the public review mechanism
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
August 15, 2023 - not have the expertise or the time to do the full
diagnostic interview required for diagnosis, they … KQ 1: How accurate are assessment tools compared to reference standard methods to identify
OCD in symptomatic … KQ 2a How do the effectiveness and harms vary with patient, family, social, or other
characteristics … Technical Experts do not do analysis of any kind;
neither do they contribute to the writing of the report … They do not review the report, except as
given the opportunity to do so through the peer or public review