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effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
January 01, 2012 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … or may hold potential to diagnose, treat, or otherwise
manage a particular condition or to improve … on topics and issuing topic drafts to a small group of various experts (selected topic by
topic) to … Copayments vary according to
the terms of a patient’s benefits. … limitations of the new therapy and how it affects their care.
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effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
June 01, 2013 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … or may hold potential to diagnose, treat, or otherwise
manage a particular condition or to improve … a national Healthcare
Horizon Scanning System to generate information to inform comparative-effectiveness … on topics and issuing topic drafts to a small group of various experts (selected topic by
topic) to … lack of progress in basic understanding of these disorders and how to
diagnose and treat them.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
August 01, 2014 - was observed
and how stable that effect is likely to be in the face
of future research. … ge
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do … to how
interventions are described and implemented. … It is also unclear
how similar groups of children would respond to differing
levels of intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … be a
major barrier to acceptance. … availability of lipid-lowering pharmacotherapies used in the general population, many patients
with HoFH do … three
publications: a review article and two case reports. … Experts’ opinions differed somewhat about how much this
intervention would disrupt health care delivery
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
November 01, 2012 - Do harms differ by the duration of the treatment and
time of followup? … Tables A
and C show how many studies examined each outcome,
estimated effect sizes, and our level of … Evidence from a single study was inconclusive
for how racial differences affect treatment outcomes of … Average scores do not reveal
how many or which types of patients develop disability or
experience clinically … Average scores do
not reveal how many or which patients develop
disability or experience clinically
-
effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
January 01, 2012 - and conclusions in this document
are those of the authors, who are responsible for its content, and do … regional research centers), and
uncertainty about how it could really affect health outcomes because … Q sensor (a device to measure skin’s conductivity) can detect how well children
with autism can recognize … research centers), and uncertainty about how it could
really affect health outcomes because of its … Regarding how well this intervention could address the unmet need to accurately diagnose ASD
and distinguish
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … from
the U.S. market because of concerns about safety and efficacy, which might negatively affect how … nonsurgical option for
patients who do not wish to undergo bariatric surgery. … Several experts commented that
patients would require initial training on how to properly self-inject … Other than
initial training on how to use the injection pen, there is no reason to anticipate disruption
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendi-c.xlsx
January 01, 2024 - achieve a urine volume equal to or greater than 2 L a day; All patients received water that was not … with pill counts but authors do not report actual levels of adherence Passage of new stones NR Appearance … Less than half of recurrences were symptomatic, but authors do not report specific numbers At 3 years … with pill counts but authors do not report actual levels of adherence Passage of new stones NR Appearance … done to consider the 6 subjects who left for AEs as treatment failures; Unclear how the other 17 subjects
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - i.e., Low, Medium, and High) for updating any given CER is
based on the following two criteria:
• How … • How out of date are conclusions (e.g., consideration of magnitude/direction of changes in
estimates … We could not determine if
this means that there is a lack of effect versus a
lack of power to show … How quickly do systematic reviews go
out of date? A survival analysis. … We could not determine if this means that there is a
lack of effect versus a lack of power to show that
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - depressive episodes, antidepressants do not appear to be effective in bipolar
disorder.25 Hence, we … How future
research efforts are organized, funded, and conducted are crucial issues. … Further, existing systems of coding (e.g., ICD-9) do not capture a
variety of important nuances of clinical … those that do
not. … 5 on a 1 to 5 scale
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
December 05, 2013 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … the payers listing policies for MSCs for OA consider the
therapy investigational at this time and do … device depends
on how much it has been manipulated after collection. … (IND), investigational device exemption (IDE), or new
biologic, depending on how FDA categorizes the … not
responding to conservative therapy and who do not want to undergo knee replacement.
-
effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
January 01, 2012 - and conclusions in this document
are those of the authors, who are responsible for its content, and do … a Web site to order the product, at a cost of roughly $485 for three vials, plus
shipping.
4
Patients … upon which to base a medical treatment. … Experts with a clinical perspective believe that this therapy has a very high potential to disrupt … Experts’ opinions were divided in assessment of how TSO might affect the per-patient costs of
treating
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - In routine clinical practice, how-
ever, adherence to chronic therapy is often suboptimal.15–17
Because … DMARD; and (2) time to switching to a different DMARD
regimen. … therapies resulted in a switch to a different
DMARD regimen. … to a different DMARD regimen (Table 2). … Why randomized controlled clinical trials do not
depict accurately long-term outcomes in rheumatoid arthritis
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - Investigators should lay out a framework
for how the integrated intervention addressed both
OSH and … to a particular population
of workers. … groups of workers or work settings
might help clarify not only the SOE for interventions
but also how … In terms of outcomes, future studies should
do a better job of measuring safety-related outcomes
to … Finally, we urge investigators
to plan ahead for how to handle differences between
worker groups at
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
January 01, 2015 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … Many
patients with T2DM do not meet treatment goals and require additional therapy with one of two … the World Health Organization, people with diabetes who do not
receive appropriate eye care have a … Researchers estimate
that two-thirds of diabetic patients do not achieve adequate glycemic control … inform the sponsors of
APDS IDE studies on how to support a PMA for “single patient use in the home
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - Decisions about whether to revascularize and how to
revascularize patients with PAD depend on a number … Do the safety concerns vary by subgroup
(age, sex, race, risk factors, comorbidities, anatomic
location … In adults with CLI due to PAD:
a. … a small
effect, 0.5 equates to a medium effect, 0.8 equates to a
large effect, and effects larger than … There do not appear to be significant differences in
mortality or limb outcomes between endovascular
-
effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
January 01, 2012 - According to the Epilepsy Foundation, about 20% of patients with epilepsy
do not respond to available … However, experts were divided on how likely clinicians would be to offer the therapy. … access to
treatment for patients who do not live in close proximity to a hospital. … In terms of patient acceptance, a health systems expert questioned, “How does it
affect speech? … Now all
it has to do is convince the world they're
necessary. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
January 01, 2011 - predict a response to IV iron treatment. … ) to predict a response to IV iron treatment … data are sufficient and
reliable, decision analysis could be used to assess how
employing combinations … how using
combinations of
different markers
to guide iron
management
strategies might
influence … all currently available
laboratory biomarkers of iron status (either newer or
classical markers) do
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_executive.pdf
December 01, 2015 - change how patients think about sleep by identifying, challenging,
and replacing dysfunctional beliefs … se
b
ut
n
ot
5
m
g
do
se
a
t w
ee
k
4)
. … systematically assessed observational studies and case
reports of nonbenzodiazepine hypnotics. … certain
sleep outcomes,54 achievement of sleep outcomes below
specified value), it is not always clear how … Findings of safety in our review do not
rule out the risk of serious adverse effects associated with
-
effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
January 01, 2012 - and
conclusions in this document are those of the authors, who are responsible for its content, and do … intervention.
16-22
Overall, experts stated that current OA therapies treat
only the symptoms and do … intervention.
40-46
Overall, experts stated that current therapies for OA treat
only the symptoms and do … In general, the experts thought that tofacitinib would not shift how RA is treated or managed. … Experts all thought tofacitinib would have a large impact on costs, but diverged in how the
impact