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cds.ahrq.gov/sites/default/files/cds/artifact/1146/Warfarin%20and%20SSRIs%20Graph%20V.%205.pdf
March 11, 2019 - Warfarin
Type of
Antidepressant
Assess risk and
take action if
necessary
Increased GI and
non-GI bleeding … risk is possible
Assess risk and
take action if
necessary
Increased GI and
non-GI bleeding … risk is possible
No special
precautions
Increased
bleeding risk
unlikely
And
SNRIs: … antagonists
- Anti-platelet medications
Does patient have
one or more risk
factors for major
bleeding … No Yes
Use only if
benefit
outweighs risk
Increased GI and
non-GI bleeding
risk is likely
-
cds.ahrq.gov/sites/default/files/cds/artifact/476/Pain%20Management%20Summary%20Clincial%20Decision%20Support%20Toolkit_for%20Repository.xlsx
January 01, 2003 - trimester
O46.91 Antepartum hemorrhage, unspecified, first trimester
O46.92 Antepartum … hemorrhage, unspecified, second trimester
O46.93 Antepartum hemorrhage, unspecified, third trimester … , first trimester
O44.02 Complete placenta previa NOS or without hemorrhage, second trimester … with hemorrhage, first trimester
O44.12 Complete placenta previa with hemorrhage, second trimester … previa with hemorrhage, unspecified trimester
O30.021 Conjoined twin pregnancy, first trimester
-
cds.ahrq.gov/sites/default/files/cds/artifact/476/Pain%20Management%20Summary%20Clincial%20Decision%20Support%20Toolkit_for%20Repository_0.xlsx
January 01, 2003 - trimester
O46.91 Antepartum hemorrhage, unspecified, first trimester
O46.92 Antepartum … hemorrhage, unspecified, second trimester
O46.93 Antepartum hemorrhage, unspecified, third trimester … , first trimester
O44.02 Complete placenta previa NOS or without hemorrhage, second trimester … with hemorrhage, first trimester
O44.12 Complete placenta previa with hemorrhage, second trimester … previa with hemorrhage, unspecified trimester
O30.021 Conjoined twin pregnancy, first trimester
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cds.ahrq.gov/sites/default/files/cds/artifact/1146/Warfarin-Antidepressants%20MDIA%20Implementation%20Guide.docx
August 29, 2020 - Although there are concerns regarding bleeding risks associated with warfarin and antidepressants, only … some antidepressants increase the risk of bleeding when given concurrently with warfarin. … If so, the algorithm then determines whether the patient has one or more risk factors for major bleeding … risk is likely
1527
16
Warfarin / SSRI or SNRI with major bleeding risk factors
Warfarin Sodium … 10 MG Oral Tablet
Escitalopram 20 MG Oral Tablet
History of GI Bleeds = Acute peptic ulcer with hemorrhage