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121. Exhibit 2.5 Circulatory Conditions
     hcup-us.ahrq.gov/reports/factsandfigures/figures/2005/2005_2_5a.jsp
     January 01, 2005 - disease) 1,109.6 49.551 1 691.0 33.193 1 62.3 418.4 16.940 3 37.7 108 Congestive … heart failure, nonhypertensive 1,090.2 25.445 2 524.4 12.908 2 48.1 565.6 13.092

122. Acute Renal Failure Hospitalizations, 2005-2014 #231
     hcup-us.ahrq.gov/reports/statbriefs/sb231-Acute-Renal-Failure-Hospitalizations.jsp
     November 01, 2017 - 366.7 Acute and unspecified renal failure 1 281,500 21.4 2 504,600 13.5 79.3 Congestive … heart failure; nonhypertensive 3 91,200 6.9 3 230,700 6.2 153.0 Diabetes mellitus … Congestive heart failure was the third most common principal diagnosis among stays with a secondary diagnosis … heart failure, acute myocardial infarction, dysrhythmias, and coronary atherosclerosis) and two infections … Congestive heart failure; nonhypertensive—acute renal failure: $17,200; no acute renal failure: $9,600

123. Section 2
     hcup-us.ahrq.gov/reports/factsandfigures/2009/section2_TOC.jsp
     January 01, 2009 - Pneumonia (3.0 percent of all stays) and congestive heart failure (2.6 percent) were the second and third … Three circulatory diseases—congestive heart failure, coronary atherosclerosis, and cardiac dysrhythmias

124. Clinically Enhanced Data Lab Data Requirements (pdf file)
     hcup-us.ahrq.gov/datainnovations/clinicalcontentenhancementtoolkit/mn12.pdf
     April 29, 2014 -  If only ADHF (Acute Decompensated Heart Failure) data is included, patients with any of the following … ICD-9-CM codes as a principal diagnosis should be included: - 428.xx heart failure - 398.91 rheumatic … heart failure - 402.01, 402.11, 402.91 hypertensive heart failure - 404.01, 404.03, 404.11, 404.13 … , 404.91, 404.93 hypertensive heart failure and kidney failure  Optionality: R=Required, O=Optional

125. Ff 2009 Exhibit2 5 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2009/pdfs/FF_2009_exhibit2_5.pdf
     January 01, 2009 - 2009 All payers, total stays* 34,679 39,435 100% 100% 14% Medicare 12,618 14,708 100% 100% 17% ‡ Congestive … heart failure 757 762 6% 5% 1% Pneumonia 703 643 6% 4% -9% Septicemia 276 … Medicare:  Congestive heart failure (CHF) was the most common principal diagnosis among stays with

126. Har 2005 (pdf file)
     hcup-us.ahrq.gov/reports/annualreport/HAR_2005.pdf
     January 01, 2005 - These stays were for diagnoses that included coronary artery disease, congestive heart failure, heart … These six conditions (coronary artery disease, heart attack, congestive heart failure, irregular heart … Four heart-related diagnoses—coronary artery disease, congestive heart failure, non-specific chest pain … heart failure. … ■ Women were more likely to be hospitalized for: congestive heart failure non-specific chest

127. Statistical Brief #140
     hcup-us.ahrq.gov/reports/statbriefs/sb140.jsp
     August 01, 2012 - The readmission rate for heart failure following an index AMI was more than twice as high for older patients … Females had a 67 percent higher readmission rate for heart failure, but their readmission rate for scheduled … In 2009, heart failure and shock was the most common reason (13.4 percent) for these readmissions, followed … Heart failure and shock is defined by MS-DRGs of Heart Failure and Shock with and without complications … Reasons for readmission in table 3 (other than AMI, PTCA or CABG and heart failure or shock, which are

128. Statistical Brief #103: Hospital Utilization among Oldest Adults, 2008 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb103.pdf
     December 01, 2010 - ■ Congestive heart failure was the most common reason for hospitalization among 75–84 year olds … rate** Top 20 principal diagnoses, CCS category Rate per 1,000 population* Relative rate** Congestive … heart failure 23.2 2.2 Congestive heart failure 44.4 4.3 Pneumonia 19.7 2.1 Pneumonia 35.9 3.8 Irregular … Organization, and Markets, Healthcare Cost and Utilization Project, Nationwide Inpatient Sample, 2008 Congestive … heart failure (CHF) was the most common reason for hospitalization among 75–84 year olds (23.2 stays

129. Statistical Brief #103
     hcup-us.ahrq.gov/reports/statbriefs/sb103.jsp
     December 01, 2010 - Congestive heart failure was the most common reason for hospitalization among 75–84 year olds (23.2 stays … rate** Top 20 principal diagnoses, CCS category Rate per 1,000 population* Relative rate** Congestive … heart failure 23.2 2.2 Congestive heart failure 44.4 4.3 Pneumonia 19.7 2.1 Pneumonia … Markets, Healthcare Cost and Utilization Project, Nationwide Inpatient Sample, 2008 Congestive … heart failure (CHF) was the most common reason for hospitalization among 75–84 year olds (23.2 stays

130. Section4 2 (pdf file)
     hcup-us.ahrq.gov/reports/factsandfigures/2007/pdfs/section4_2.pdf
     January 01, 2007 - newborn infant) 8.1 12.7 4.6 3.8 80.3 Circulatory Congestive … heart failure 6.8 10.5 4.5 3.0 21.1 Cardiac dysrhythmias

131. Title: (pdf file)
     hcup-us.ahrq.gov/datainnovations/MNAbstractFinal.pdf
     September 29, 2013 - State: Minnesota Title: Using Clinically Enhanced Claims Data to Guide Treatment of Acute Heart … Failure Principal Investigator: Mark Sonneborn Organization: Minnesota Hospital Association Project … analysis of alternative drug regimens used to treat patients hospitalized with acute decompensated heart … failure will be performed using the clinically enhanced administrative hospital discharge database. … Because of the complexity of heart failure and the therapies used to manage it, this study will be an

132. Most Frequent Principal Diagnoses for Inpatient Stays in U.S. Hospitals, 2018 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb277-Top-Reasons-Hospital-Stays-2018.pdf
     January 01, 2018 - Two circulatory conditions—heart failure and AMI—ranked in the top 10 principal diagnoses in 2018 and … Heart failure and osteoarthritis each accounted for 4 percent. … Five circulatory conditions were among the 20 most common principal diagnoses in 2018: heart failure … failure 140,400 980.9 3 Heart failure 113,600 697.7 4 Acute myocardial infarction 111,000 775.6 4 … failure 248,700 2,877.7 2 Heart failure 307,000 2,448.5 3 Pneumonia 128,000 1,481.7 3 Urinary tract

133. Most Common Diagnoses and Procedures in U.S. Community Hospitals, 1996
     hcup-us.ahrq.gov/reports/natstats/commdx/table2a.htm
     February 11, 2011 - Congestive heart failure, nonhypertensive D5. Acute myocardial infarction D6. … Congestive heart failure, nonhypertensive [108] 990,085 100.00 2.84

134. Table 2 (pdf file)
     hcup-us.ahrq.gov/toolssoftware/comorbidity/Table2-FY12-V3_7.pdf
     February 01, 2017 - 3.4 Added 265 1 The comorbidity category Congestive … Heart Failure shares diagnosis codes with Hypertension (402.01,402.11,402.91,404.01,404.11,404.91) and … diagnosis codes with Renal Failure (403.01,403.11,403.91,404.02,404.12,404.92,404.03,404.13,404.93) and Congestive … Heart Failure (402.01,402.11,402.91,404.01,404.11,404.91,404.03,404.13,404.93). 3 Table 2 … Heart Failure (404.03,404.13,404.93). 6 Table 2 Definitions of Comorbidities, Elixhauser

135. Geographic Variation in Potentially Preventable Inpatient Stays for Chronic Health Conditions, 2016 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb264-Chronic-Condition-Preventable-Hospitalizations-2016.pdf
     January 01, 2016 - heart failure (CHF), and diabetes—are presented for each State. … heart failure (CHF) or diabetes … heart failure (CHF), and diabetes. … heart failure; COPD, chronic obstructive pulmonary disease Source: Agency for Healthcare Research and … heart failure, 2016 Notes: Substate region-level data are unavailable for States in grey.

136. Trends in Hospital Inpatient Stays in the United States, 2005-2014 (pdf file)
     hcup-us.ahrq.gov/reports/statbriefs/sb225-Inpatient-US-Stays-Trends.pdf
     December 01, 2016 - ■ Septicemia, osteoarthritis, and congestive heart failure were the most common nonmaternal, nonneonatal … heart failure decreased from 2005 to 2014. … Stays for congestive heart failure decreased by 14.4 percent (from 1,053,100 to 901,400). 12 … heart failure; nonhypertensive 221,000 4.7 Congestive heart failure; nonhypertensive 195,400 3.8 … heart failure; nonhypertensive 565,600 6.9 Septicemia 543,700 7.6 2 Pneumonia 533,700 6.6 Congestive

137. Trends in Hospital Readmissions for Four High-Volume Conditions, 2009-2013 #196
     hcup-us.ahrq.gov/reports/statbriefs/sb196-Readmissions-Trends-High-Volume-Conditions.jsp
     November 01, 2015 - heart failure (CHF), and pneumonia among Medicare beneficiaries. … heart failure (CHF), chronic obstructive pulmonary disease (COPD), and pneumonia. … heart failure, non-hypertensive 782,079 183,534 2,728 23.5 2 Schizophrenia and other … heart failure, chronic obstructive pulmonary disease, and pneumonia, and for all index admissions for … The rate of readmission for congestive heart failure was 25.1 in 2009, 24.7 in 2010, 24.8 in 2011, 24.0

138. Table1 (pdf file)
     hcup-us.ahrq.gov/reports/natstats/commdx/table1.pdf
     February 11, 2011 - Congestive heart failure, nonhypertensive [108] 644,789 4.74 1.85 3.82 4.9 3.5 $7,669 … Congestive heart failure, nonhypertensive [108] 43,234 6.64 0.12 2.24 6.7 5.0 $17,393 … Congestive heart failure, nonhypertensive [108] 3,021 0.63 0.01 4.83 8.6 6.9 $32,055 … Congestive heart failure, nonhypertensive [108] 27,240 5.85 0.08 24.33 8.4 5.9 $23,400 … Congestive heart failure, nonhypertensive [108] 2,911 0.79 0.01 8.02 16.1 13.2 $66,747

139. Most Common Diagnoses and Procedures in U.S. Community Hospitals, 1996
     hcup-us.ahrq.gov/reports/natstats/commdx/table1a.htm
     February 11, 2011 - Congestive heart failure, nonhypertensive [108] 644,789 4.74 1.85 … Congestive heart failure, nonhypertensive [108] 43,234 6.64 0.12 … Congestive heart failure, nonhypertensive [108] 3,021 0.63 0.01

140. Lab Data Requirements
     hcup-us.ahrq.gov/datainnovations/clinicalcontentenhancementtoolkit/mn12.jsp
     September 01, 2014 - If only ADHF (Acute Decompensated Heart Failure) data is included, patients with any of the following … ICD-9-CM codes as a principal diagnosis should be included: 428.xx heart failure 398.91 … rheumatic heart failure 402.01, 402.11, 402.91 hypertensive heart failure 404.01, 404.03, 404.11 … , 404.13, 404.91, 404.93 hypertensive heart failure and kidney failure Optionality: R=Required,