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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-screening-november-2016
August 06, 2015 - , it illustrates whether treatment of genital herpes leads to improved health outcomes or potential harms … What are the harms of serologic screening for HSV-2 or paired testing for HSV-1 and HSV-2 in asymptomatic … What are the harms of serologic screening for HSV-2 or paired testing for HSV-1 and HSV-2 in asymptomatic … What are the harms of preventive medications and behavioral counseling interventions for reducing future … What are the harms of preventive medications and behavioral counseling interventions for reducing neonatal
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/wpMBNddeRLwrGpQfFL_Skh
February 01, 2016 - The Task Force reviewed research studies on the
potential benefits and harms of ASD screening in
young … what the Task Force learned: There is
not enough evidence available on the potential
benefits and harms … The Task Force also found little evidence about potential harms of screening very young children for … Overall, however, the
potential harms of screening and treating children identified through screening … The grades are based on the quality and strength of the evidence about the potential benefits and harms
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aRJ-3-AWuVvmC_kmoGCVHp
who are
pregnant and their
infants (screening)
Research is needed to assess the benefits and
harms … outcomes:
Serious harms;
harms leading to
discontinuation;
overtreatment
Research is needed to … assess the benefits and
harms of routine iron supplementation in
asymptomatic pregnant persons without … levels;
low birth weight,
small for gestational
age, and preterm
delivery
KQ2: More serious
harms … ; harms
leading to
discontinuation;
accidental overdose
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/d8DVjQhw6JgjWaBtED97s6
U.S. primary care
settings or
referrable from
primary care
Research is needed on the long-term harms … and non-
Hispanic Black
children and
adolescents)
Outcomes:
KQ4: Serious treatment-
related harms … at any time
after initiation of
intervention (e.g., GI-
related harms, medical
issues requiring … hospitalization or urgent
medical treatment)
Harms associated with
labeling or stigma (e.g.,
increased … of
weight loss after behavioral interventions and
assessment of long-term (>5 years) benefits
and harms
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/hepatitis-b-virus-infection-screening-2004
February 15, 2004 - Potential harms of screening include labeling, although there is limited evidence to determine the magnitude … As a result, the USPSTF concluded that the potential harms of screening for HBV infection in the general … [the service] improves important health outcomes and concludes that benefits substantially outweigh harms … evidence that [the service] improves important health outcomes and concludes that benefits outweigh harms … The USPSTF found at least fair evidence that [the service] is ineffective or that harms outweigh benefits
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KSYrhQuAswGjTww_4sDFGZ
December 01, 2007 - Data Extraction: No new evidence was found on benefits or harms
of screening. … Two reviewers extracted data from studies on the
harms of early treatment, including adverse effects … Limitations: The nonsystematic search may have missed some
smaller studies on the benefits and harms … 2) What are the harms of screen-
ing and/or early treatment of high blood pressure? … To de-
termine whether the benefits of screening for hypertension
continue to outweigh the harms, the
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/hEp2uYfD9KRhYTY5fGr8Tp
October 15, 2018 - It bases its recommendations on the evidence of both the ben-
efits and harms of the service and an … and coverage
decisions involve considerations in addition to the evidence of clini-
cal benefits and harms … with 0.5% erythromycin ophthalmic ointment is not as-
sociated with serious harms. … Evidence is lacking, of poor quality, or conflicting, and the balance of
benefits and harms cannot be … Possible harms include the potential for antimicrobial resistance
to treatment medication.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - ; some harms (including overdose risk) were dose-dependent. … Harms and Adverse Events
a. … harms, infections, cardiovascular events, cognitive harms, and
psychological harms (e.g., depression … (including overdose, substance use
disorder and misuse; other harms (including gastrointestinal harms … ,
cognitive harms, and psychological harms, including depression and suicidality).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/vision-in-children-ages-6-months-to-5-years-screening
September 05, 2017 - Balance of Benefits and Harms
The USPSTF concludes with moderate certainty that vision screening to … Limited evidence suggests that screening can potentially reduce psychosocial harms. … Harms of Early Detection and Treatment
The USPSTF found adequate evidence to assess harms of vision … The USPSTF found inadequate evidence on the harms of treatment in children younger than 3 years. … The USPSTF found adequate evidence to bound the potential harms of treatment as small.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cognitive-impairment-in-older-adults-screening
October 19, 2017 - What are the harms of screening for cognitive impairment in community-dwelling older adults? … KQ 3: Paradoxical effects (unwanted or unexpected direction of effects of outcomes), psychological harms … (depression, anxiety), and harms due to labeling (psychological harms, insurance status, loss of driving … ), paradoxical effects (unwanted or unexpected direction of effects of outcomes), and psychological harms … Cost-related outcomes
KQs 3, 5: Patient or family/caregiver dissatisfaction (other than psychological harms
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
June 23, 2016 - Moving from left to right, the figure depicts the harms that may result from supplementation with vitamin … Are there harms of supplementation with vitamin D or calcium alone or vitamin D combined with calcium … Do the harms of supplementation vary by:
Dose or dosing interval? … In response to comments, the USPSTF revised the key question regarding harms to remove indication of … an assumption of harms with vitamin D or calcium supplementation.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/BwAo_shwmJLSRguyWxaXpP
July 01, 2007 - .
*= critical evidence gap
Harms of detection and early treatment: Potential harms of screening … Adverse effects from
lipid-lowering medications and low-fat diets, including potential long-term harms … USPSTF assessment: The USPSTF was unable to determine the balance
between potential benefits and harms … the evidence on accuracy of screening tests including family history, efficacy of
treatment, and harms … during monitored low-fat diet interventions.2 Physical activity interventions
have had no reported harms
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … The long-term benefits and harms of statin use in children and adolescents are unknown. … Balance of Benefits and Harms
The USPSTF concludes that the current evidence is insufficient and that … Harms of Early Detection and Treatment
The USPSTF found inadequate evidence to assess the harms of … There is inadequate evidence on the effectiveness and harms of long-term treatment and the harms of screening
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2002
July 08, 2002 - Clinicians should inform patients of the potential benefits and harms of chemoprevention. … The USPSTF concluded that the balance of benefits and harms may be favorable for some high-risk women … but will depend on breast cancer risk, risk for potential harms, and individual patient preferences. … The USPSTF concluded, however, that the potential harms of chemoprevention may outweigh the potential … In general, the balance of benefits and harms of chemoprevention is more favorable for:
Women in
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www.uspreventiveservicestaskforce.org/Home/GetFile/1/16813/prostate-cancer-models-overview/pdf
May 01, 2018 - studies have the potential to inform our understanding of
factors that influence the benefits and harms … Because prostate cancer has (or can have) a
long period when it is detectable but asymptomatic, harms … Data on estimated harms were not presented. … Reduce the harms and keep the benefit. Int J Cancer. 2015;136(7):1600-7. … Reduce the harms and keep the benefit.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/qSyg242Cz-X9DDwZg6GEhP
Recommendation
For all populations, evidence is insufficient to assess the benefits and harms … high-sensitivity fecal occult blood testing every 3 years
• Screening colonoscopy every 10 years
Balance of Harms … and Benefits
The benefits of screening outweigh the
potential harms for 50- to 75-year-olds.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/suicide-risk-in-adolescents-adults-and-older-adults-screening
May 20, 2014 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … , and the balance of benefits and harms of screening cannot be determined. … Harms of Detection and Early Intervention or Treatment
Evidence on the possible harms of screening … Potential Harms
Evidence on the potential harms of screening for suicide risk is insufficient. … Other potential harms of screening include harms that may result from treatment in persons with screen-detected
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Y5p8ZXy2ydg_VZMUfxbJ-6
April 25, 2017 - of screening for
preeclampsia, the effectiveness of risk prediction tools, and the benefits and harms … Harms of Early Detection and Treatment
The USPSTF found adequate evidence to bound the potential harms … This assessment was based on the known harms of treatment
with antihypertension medications, induced … labor, and magnesium
sulfate; the likely few harms from screening with blood pressure mea-
surements; … The
USPSTF found inadequate evidence on the harms of risk prediction.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/decision-modeling-for-uspstf_0.pdf
July 01, 2016 - Before deciding whether
to use decision modeling, the USPSTF assesses whether the
benefits and harms … ; assessing the degree of certainty the evidence
provides for both benefits and harms; and determining … Evidence is lacking, of poor quality, or
conflicting, and the balance of benefits and harms cannot
be … What are the potential harms, and how often do they occur?
8. … Aspirin
Use in Adults: Cancer, All-Cause Mortality, and Harms.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/lipid-disorders-screening-children-adolescents-final-rec-bulletin.pdf
July 18, 2023 - Grade in this recommendation:
I: The balance of benefits and harms
cannot be determined. … foundation of Task Force recommendations is a careful assessment of the evidence on both benefits and
harms … There is limited evidence on the benefits and harms of screening all children and teens without symptoms … In addition, the potential long-term harms of treating children and adolescents to
lower cholesterol