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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - Congress, was to evaluate the evidence on benefits
and harms of cannabinoids and similar plant-based … • Longitudinal studies on opioids to evaluate
longer-term outcomes, including associated
harms … • Longitudinal outcome studies on opioids,
including harms (e.g., refractory opioid
dependence, … • Although evidence was limited, serious harms
were not reported for either program. … • Systematic reviews of harms (regardless of
indication) report that acetaminophen,
prednisolone
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1
December 07, 2021 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … The USPSTF determined there was insufficient evidence to assess the balance of benefits and harms of … are not invasive and unlikely to cause serious harms. … Harms of Screening
No studies reported harms of screening in children younger than 5 years who were … application as no greater than small, based on limited evidence of harms.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
August 01, 2023 - For harms, 9 studies were eligible: 1 randomized clinical trial (n = 431) reported on variations in twin … The new evidence was consistent with previously reviewed evidence on benefits and harms. … For harms, 9 studies were eligible; 1 randomized clinical trial (n = 431) assessed variations in twin … Harms of Folic Acid Supplementation
No study of harms (multiple gestation, autism, and maternal cancer … This new evidence is consistent with previously reviewed evidence on the benefits and harms of folic
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mggnaKHr496c8QCgHe9-tm
May 01, 2021 - commissioned a reaffirmation evidence update that focused on targeted key
questions for benefits and harms … Harms of early detection and
intervention and treatment
• The USPSTF found inadequate direct evidence … on the harms of screening for and treatment of asymptomatic COPD.
• Given that the opportunity costs … In
addition, 2 observational studies addressed the harms of medica-
tions. … Comments asked for clarification on the benefits and
harms of COPD treatment.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/sCkggReHbVWXtLoqWhEPrh
July 01, 2023 - Task Force concluded that the current evidence was
insufficient to assess the balance of benefits and harms … performance of risk assessment tools to identify children who are at increased risk for IDA;
• The harms … Outcomes at one year include
cognitive and functioning measures and serum ferritin and hemoglobin levels; harms … Rates of iron deficiency and
anemia at 6 months and intervention-related harms are reported.5 Three
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Qd4Zm2Uk2LDuBPa9yyFBRM
January 01, 2014 - USPSTF concludes that the current evi-
dence is insufficient to assess the balance of benefits and harms … Harms of Detection and Early Treatment
The USPSTF found inadequate evidence on the
harms of screening … No study reported on harms from the
screening test or from false-positive or false-negative re-
sults … Potential diagnostic harms are primarily related to
the harms of biopsy for suspected oral cancer or … Therefore, the USPSTF was unable to determine
the balance of benefits and harms.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - • Harms reporting was limited by sample sizes and short followup duration though
most studies did … not find frequent serious harms. … to treatment, or the benefits or harms of endometrial
surveillance for patients using hormonal therapies … examined the evidence for Key Questions related to
GSM screening (KQ1), treatment effectiveness and harms … but serious harms, though most studies did not find evidence of
frequent serious harms.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - What is the frequency and severity of harms addressed by the patient and family engagement
PSPs? … What measures or indicators have been used to examine the harms associated with the target
of the patient … What patient and family engagement PSPs have been used to prevent, report, or mitigate
harms to patients … for the patient and family engagement PSPs that have been used to
prevent, report or mitigate the harms … What is the frequency and severity of harms addressed by the patient and family engagement PSPs?
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/autism-spectrum-disorder-in-young-children-screening
February 16, 2016 - Harms of Early Detection and Intervention or Treatment
The USPSTF found that the harms of screening … Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be … Potential Harms
Although there is limited evidence about the harms of screening for ASD in children … Potential Harms of Screening and Treatment
The USPSTF found little evidence on the harms of screening … Finally, other comments focused on the low cost and lack of harms associated with screening.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
October 05, 2018 - Osteoporosis treatment harms vary by drug class. … >100 subjects for rare
harms and >1000 subjects
for other harms
KQ 5:
Effect of
drug
treatment … Timing Setting Study Design
KQ 7:
Harms of
drug
treatment
holidays
KQ8:
Predictors
of harms … >100 subjects for rare
harms and >1000 for other
harms
Abbreviations: ALP = alkaline phosphatase … )
• Harms (Serious adverse events and specific harms as listed in Table 2)
Outcome
predictors
(
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Harms of tricyclic antidepressants versus placebo
Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR
Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo
Author, Year Quality Pain Population Drug Assessment Time (Wk) Time … Harms of lidocaine patch versus placebo
Author, Year Quality Pain Population Drug Assessment Time (Wk
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
February 09, 2023 - What are the harms of screening for IPV in adolescents and adults? … What are the harms of interventions for IPV in adolescents and adults? … What are the harms of screening for abuse and neglect in older and vulnerable adults? … What are the harms of interventions for abuse and neglect in older and vulnerable adults? … of screening or identification
KQ 5: Any harms that result from interventions, such as increased
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - The magnitude of harms depends on the presence of risk factors for bleeding. … Evidence on the benefits and harms of initiating aspirin use in older adults is limited. … harms for adults older than 70 years are significant. … Meanwhile, bleeding harms may occur in the short term. … Aspirin Use in Adults: Cancer, All-Cause Mortality, and Harms.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-july-2014
July 08, 2014 - Balance of Benefits and Harms
The harms of screening for asymptomatic carotid artery stenosis outweigh … for carotid artery stenosis and treatment with CEA can cause harms. … Although screening with ultrasonography has few direct harms, all screening strategies, including those … Potential Harms of Screening and Treatment
No studies examined the direct harms of screening. … Although angiography is less commonly used now as a confirmatory test, harms from it occurred in 2 of
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/impaired-visual-acuity-in-older-adults-screening-2016
March 01, 2016 - Harms of Detection and Early Treatment
The USPSTF found inadequate evidence on the harms of screening … Risk factors for AMD include smoking, family history, and white race. 1
Potential Harms
The harms … Overall, the potential for harms from treatment are small to none. … Harms of cataract surgery include posterior lens opacification and endophthalmitis. … Data on harms of treatment of refractive error in older adults are limited.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/yvJquSQ54yDQkQqrrLroPA
November 01, 2013 - recommendation statement summarizes what the
Task Force learned about the potential benefits and
harms … of this screening: There is not enough evidence
to determine the potential benefits and harms of
screening … Potential Benefits and Harms
The Task Force reviewed studies that looked at the accuracy of screening … The Task Force found very little evidence on the potential harms from screening or the tests used in … They also are based on the size of the potential benefits and harms.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/N3VeYbr4ZdhZfqsw3ErLHE
November 01, 2014 - and stenting (CAAS), the benefits from
medications added to current standard medical therapy, and the
harms … for CAS and treatment with CEA can cause harms. … The harms of screening for asymptomatic carotid artery stenosis outweigh the benefits. … Potential Harms of Screening and Treatment
No studies examined the direct harms of screening. … Other important harms after surgical intervention for
CAS include MI and surgical complications.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan31/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation-september-2015
July 15, 2013 - Harms of routine supplementation are examined as an offshoot arrow. … Harms of screening are examined as an offshoot arrow. … What are the harms of routine iron supplementation in pregnant women? … What are the harms of screening for iron deficiency anemia in pregnant women? … What are the harms of iron treatment in pregnant women?
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-2012
May 15, 2012 - Harms of Detection and Early Treatment
Harms Related to Screening and Diagnostic Procedures
Convincing … Many of these harms are common and persistent. … harms, does not reflect current clinical practice in the United States. … do not outweigh the harms. … Other harms of radiation, such as bowel damage, are not shown.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - Analytic Framework
* Harms … false-positive results, anxiety and effects of labeling, and partner discord, abuse, or violence. † Harms … What are the harms of screening for HIV infection in pregnant women? … What are the harms of currently recommended antiretroviral therapy regimens given during pregnancy to … will focus on the benefits and harms of treatment with antiretroviral therapy.