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effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - harms, infections,
cardiovascular events, cognitive harms, and
psychological harms (e.g., depression … harms, infections, cardiovascular events,
cognitive harms, and mental health harms (e.g.,
depression … harms, infections,
cardiovascular events, cognitive harms, and
mental health harms (e.g., depression … Harms of opioids vs. … Harms of opioids vs.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan108/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
October 16, 2014 - Folic acid supplementation may result in harms (key question 2). … Are there harms associated with folic acid supplementation to the mother, fetus, neonate, or child? … Do the harms of folic acid supplementation differ by dosage, timing, or duration of therapy? … with micronutrients (e.g., multivitamin, iron) in combination with folic acid for the prevention of harms … : Randomized, controlled trials; controlled clinical trials; cohort or case-control studies
Harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - • We only found one study reporting on potential harms from multicancer screening
tests. … We graded the strength of evidence as insufficient for harms based on this
single study. … This systematic review looks at whether MCSTs work, how accurate they are, and
what harms they might … KQ 4: What are the harms of screening with MCSTs? … We only found one study that looked at potential harms.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan36/carotid-artery-stenosis-screening-december-2007
January 23, 2014 - What are the harms associated with CEA or CAAS for the treatment of asymptomatic CAS?
7b. … Do the harms differ for subgroups defined by age, sex, race, or ethnicity?
7c. … Do the harms differ for subgroups defined by comorbidities?
8a. … Do the harms differ for subgroups defined by age, sex, race, or ethnicity?
8c. … Do the harms differ for subgroups defined by comorbidities?
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www.uspreventiveservicestaskforce.org/uspstf/document/ResearchPlanFinal/carotid-artery-stenosis-screening-december-2007
January 23, 2014 - What are the harms associated with CEA or CAAS for the treatment of asymptomatic CAS?
7b. … Do the harms differ for subgroups defined by age, sex, race, or ethnicity?
7c. … Do the harms differ for subgroups defined by comorbidities?
8a. … Do the harms differ for subgroups defined by age, sex, race, or ethnicity?
8c. … Do the harms differ for subgroups defined by comorbidities?
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www.uspreventiveservicestaskforce.org/uspstf/document/update-on-the-methods-of-the-us-preventive-services-task-force-estimating-certainty-and-magnitude-of-net-bene%EF%AC%81t/carotid-artery-stenosis-screening-december-2007
December 15, 2007 - It then assesses the certainty of the evidence and the magnitude of the benefits and harms. … "net benefit" (that is, benefits minus harms). … Data about harms are often obtained from observational studies because harms observed in RCTs may not … The harms of screening for carotid artery stenosis, including the harms from carotid angiography to confirm … in harms as a direct consequence of the service or for other downstream reasons.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/jaK5cMrYT_E3QkSzf93qbo
January 01, 2015 - should be based on their health history, preferences,
and how they value the potential benefits and harms … The Task Force found that there is not enough evidence to determine the balance of benefits and harms … The Task Force suggests that older women talk
with their doctor about the potential benefits and harms … Experts can interpret the evidence on the benefits and harms of screening differently. … More About the Benefits and Harms of Screening
What’s the harm of getting a mammogram?
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/dL4dSze-jDjCPgDAzQ_Byj
January 01, 2015 - should be based on their health history, preferences,
and how they value the potential benefits and harms … The Task Force found that there is not enough evidence to determine the balance of benefits and harms … The Task Force suggests that older women talk
with their doctor about the potential benefits and harms … Experts can interpret the evidence on the benefits and harms of screening differently. … More About the Benefits and Harms of Screening
What’s the harm of getting a mammogram?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
May 29, 2025 - studies
Cohort and case-control studies
What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms
In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort
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effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
May 29, 2025 - studies
Cohort and case-control studies
What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms
In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort
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psnet.ahrq.gov/node/44322/psn-pdf
June 21, 2016 - by a multidisciplinary panel and recommends that institutions promote voluntary
reporting of these harms … The authors encourage health professionals to address emotional harms with the
same rigor that has been … applied to physical harms. … Patient-centered care has been proposed as a
strategy for reducing preventable harms.
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psnet.ahrq.gov/node/60223/psn-pdf
January 01, 2021 - effects-harm-events-30-day-readmission-surgical-patients
This study examined the association of inpatient harms … (e.g., infections, medication-related harms) and 30-
day readmissions through a retrospective analysis … The authors found that the harms with the highest 30-day readmission rates were
pressure ulcers (45%
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/FpTcERTdy8h4MHDwBL9hKo
June 01, 2025 - Older and vulnerable adults:
The evidence is insufficient to assess the balance of benefits and harms … • Potential harms: Potential harms of screening for abuse in older or vulnerable adults include shame … The USPSTF found
insufficient evidence to assess the balance of benefits and harms of primary care interventions … best available evidence to help states and communities prevent IPV, support survivors, and lessen the harms … This includes
more details on the rationale of the recommendation, including benefits and harms; supporting
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/drug-use-illicit-screening
June 09, 2020 - potential harms from screening for drug use such as labeling and stigmatization. … Harms of Screening and Treatment
Screening
No studies addressed the harms of screening in adults … Few harms or serious adverse events were reported. … psychosocial interventions identified harms or adverse events. … considerations that may address these harms.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/cancer_older_adults.pdf
September 28, 2012 - of treatment, and
harms related to prioritization of medical care. … Harms of Screening Tests. … or side effects of prep), testing harms
(colon perforation, fatigue from a long testing day), and
harms … Harms of Disease Treatment. … Harms (and benefits) of screening
need to be expanded to HRQL outcomes.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
July 07, 2022 - What are the harms of routine iron supplementation during pregnancy? … What are the harms of screening for iron deficiency and iron deficiency anemia during pregnancy? … What are the harms of iron treatment during pregnancy? … ; harms leading to discontinuation; accidental overdose
Infant outcomes occurring after age 1 year … ; harms leading to discontinuation; overtreatment
Infant outcomes >1 year of age
Settings
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-screening
May 06, 2021 - What are the comparative harms of different mammography-based breast cancer screening strategies (e.g … Do the comparative harms vary by population characteristics and risk markers (e.g., age, breast density … foundational effectiveness trials of mammography screening influence conclusions about the benefits and harms … What are the harms of treatment associated with the detection of invasive breast cancer and ductal carcinoma … biopsy
Recall rate (need for further evaluation)
Overdiagnosis and overtreatment
Psychological harms
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chronic-obstructive-pulmonary-disease-screening
May 10, 2022 - ) on nonpharmacologic interventions, and 2 large observational studies (n = 243,517) addressing the harms … None of the included treatment trials that reported adverse effects found significant harms. … None of the included trials that reported adverse effects found significant harms. … of pharmacologic treatment
8 RCTs (n = 10,368)
Overall, limited data on serious harms reported in … populations suggest possible harms for LAMA or LABA initiation or use of inhaled corticosteroids
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/b9Wt9yR9GZwPafcBeBDUqg
November 25, 2024 - Caregiver abuse
is when a trusted person harms an older or vulnerable adult. … The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … What are the harms? … pregnant and postpartum people and women of reproductive age for IPV is unlikely to cause any
serious harms … There is not enough evidence to determine if there are harms associated with screening for caregiver
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ERYP-oE5C6JuSVZogm3Nyj
August 05, 2025 - The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … What are the harms? … The benefits of screening and counseling in adults far outweigh any potential harms. … Although unlikely,
possible harms could include stigma, discrimination, privacy concerns, negative … There is not enough evidence to determine the harms of screening and counseling in adolescents.