-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan95/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
September 18, 2014 - During screening, persons may also experience harms. … What are the harms of screening (e.g., labeling and false-positive or false-negative results)? … from screening (e.g., labeling, false-negative or false-positive results and related harms, including … harms
Settings
Primary care and primary care–referable settings (e.g., correctional … because its harms are well-established.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3R9N4ojm9Sk7qk8ybD3LU6
October 11, 2019 - Based on these known harms, the USPSTF determined the overall harms to be
at least small in this group … Harms of
screening and
treatment
• There is inadequate direct evidence to determine the harms of screening … indirect evidence of harms
associated with antibiotic use. … There is inadequate direct evidence to determine the
harms of screening and treatment. … However, based on the
known harms associated with antibiotic use, the overall
harms can be bounded as
-
www.ahrq.gov/sites/default/files/wysiwyg/news/events/ahrq-research-summit/brady-summit2016-plenary.pdf
September 28, 2016 - Hospital Safety and Measurable Impact
17% reduction
in HACs 87,000 lives
saved 2.1 million
patient harms … saving-lives.html
Patient Safety in the United States:
National Progress, but Harm Persists
2010: 145 Harms … /1,000 Discharges
2011: 142 Harms/1,000 Discharges
2012: 132 Harms/1,000 Discharges
2013: 121 Harms … /1,000 Discharges
2014: 121 Harms/1,000 Discharges
How AHRQ Makes a Difference
• AHRQ invests in … Clinical
Environment
Patient Safety
Research
Context &
External
Environment
Safer
Care
&
Fewer
Harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - Key Question Strength of Evidence Conclusion
GI and CV harms: Celecoxib High for GI harms vs.
nonselective … GI and CV harms: Partially
selective NSAIDs
GI harms: Moderate for
meloxicam and etodolac
(fewer trials … GI and CV harms:
Nonselective NSAIDs
GI harms: High for naproxen,
ibuprofen, and diclofenac
(consistent … Key Question Strength of Evidence Conclusion
GI and CV harms:
Nonselective NSAIDs
(continued)
CV harms … GI and CV harms: Aspirin Moderate for GI and CV
harms (many trials, but almost
exclusively in patients
-
www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
November 30, 2023 - Pregnant Persons
*Harms of screening include false-positive test results, anxiety and effects of … labeling, and partner discord, abuse, or violence. † Harms of treatment include adverse maternal and … What are the harms of screening for HIV in asymptomatic, nonpregnant adolescents and adults? … What are the harms of screening for HIV in pregnant persons? … What are the harms of currently recommended antiretroviral therapy regimens for antiretroviral-naïve
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 26, 2019 - What are the harms of aspirin use to prevent preeclampsia during pregnancy? … Do the harms of aspirin use to prevent preeclampsia vary by subpopulations defined by personal characteristics … measurements or assays (e.g., uterine artery Doppler, biomarkers)
Risk prediction model
KQ 3 (Harms … or symptoms
Maternal mortality
Measures of well-being or quality of life
Potential treatment harms … 10th percentile weight for gestational age)
Stillbirth or neonatal mortality
Potential treatment harms
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/asymptomatic-bacteriuria-in-adults-screening
September 24, 2019 - Based on the harms associated with antibiotic use, the USPSTF found adequate evidence to bound the harms … Harms of screening and treatment
There is inadequate direct evidence to determine the harms of … indirect evidence of harms associated with antibiotic use. … There is inadequate direct evidence to determine the harms of screening and treatment. … However, based on the known harms associated with antibiotic use, the overall harms can be bounded as
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/zYdjLaTCTBVUwgJTnzpVXr
May 08, 2018 - Potential harms of screening include frequent false-positive results and psychological harms. … Harms of Early Detection and Treatment
The harms of screening for prostate cancer include harms
from … Potential harms of screening include fre-
quent false-positive results and psychological harms. … biopsy, and harms from treatment. … Potential Harms
No studies have assessed the risk of harms related to screening for,
diagnosis of, or
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-children-adolescents
October 11, 2022 - Evidence is lacking, and the balance of benefits and harms cannot be determined. … As a result, the balance of benefits and harms cannot be determined. … Potential Harms
Potential harms of screening for MDD in young children or for suicide risk in children … inhibitors in children is associated with harms, specifically risk for suicidality. … small, based on the likely minimal harms of using screening tools, limited evidence of harms, and the
-
psnet.ahrq.gov/node/866848/psn-pdf
September 25, 2024 - In Conversation with Eric Thomas about Zero Harm:
Striving to Reduce Preventable Harms – Point,
Counterpoint … There are certainly harms in a very literal sense that are an intentional part of
healthcare. … There are also harms that are
unintentional and unpreventable. … We are talking about preventable harms. … ,
and our goal is to have slightly fewer harms year-over-year.
-
www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/grade-definitions
October 01, 2018 - the C recommendation has remained consistent: at the population level, the balance of benefits and harms … There is moderate or high certainty that the service has no net benefit or that the harms outweigh the … Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be … There is moderate or high certainty that the service has no net benefit or that the harms outweigh the … Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be
-
www.uspreventiveservicestaskforce.org/apps/gradedef.jsp
July 01, 2012 - recommendation has
remained consistent: at the population level, the balance of benefits and harms … moderate or high certainty
that the service has no net benefit or that the harms … The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms … the service is offered, patients should understand the uncertainty about the balance of benefits and harms … The USPSTF
found at least fair evidence that [the service] is ineffective or that harms outweigh
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/nhEwwYcy6qGYDmvs57XtTb
A biennial schedule preserves most of the benefit of
annual screening and cuts the harms nearly in half … Harms of screening include psychological harms, additional medical visits, imaging, and biopsies in women … without cancer, inconvenience due to false-positive screening results, harms of unnecessary treatment … Harms seem moderate for each age group. … Harms of BSE include the
same potential harms as
for CBE and may be larger
in magnitude.
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/DxeDM5ywg2J7SwKmETXfbX
May 01, 2021 - (USPSTF) concludes that the
current evidence is insufficient to assess the balance of benefits
and harms … Harms of early detection and
intervention and treatment
• There is inadequate evidence on the harms … No trials were identified
that directly compared harms in screened vs unscreened populations. … • There is inadequate evidence on the harms of treatment of OSA in screen-detected populations. … Commonly reported harms of treatment with positive airway pres-
sure include oral or nasal dryness,
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
May 18, 2021 - The 4 studies of screening colonoscopy that reported harms by race/ethnicity had inconsistent findings … No other studies on harms reported results by race/ethnicity. … Harms of Screening and Treatment
No studies reported on harms from stool-based tests. 9 , 10 The primary … and from harms of workup of positive screening results, such as colonoscopy. … Twenty-three studies reported on differences in harms by age, and 21 studies included persons younger
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening
May 08, 2018 - Harms of Early Detection and Treatment
The harms of screening for prostate cancer include harms from … Potential harms of screening include frequent false-positive results and psychological harms. … biopsy, and harms from treatment. … Potential Harms
No studies have assessed the risk of harms related to screening for, diagnosis of, … Potential Harms of Screening and Treatment
Potential Harms of Screening and Diagnosis
In addition
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
February 22, 2024 - Pregnant Persons
*Harms of screening include false-positive test results, anxiety and effects of … † Harms of treatment include adverse maternal and infant outcomes associated with use of antiretroviral … What are the harms of screening for HIV in asymptomatic, nonpregnant adolescents and adults? … What are the harms of screening for HIV in pregnant persons? … What are the harms of currently recommended antiretroviral therapy regimens for antiretroviral-naïve
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - They were included for the assessment of
harms if they reported on harms of treatments for which
data … (continued)
Harms: Local Wound Applications
Dressings and topical therapies Moderate Harms reported … harms by ulcer characteristics. … harms by patient characteristics. … harms by patient care setting.
-
www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/asymptomatic-bacteriuria-in-adults-screening
September 24, 2019 - Based on the harms associated with antibiotic use, the USPSTF found adequate evidence to bound the harms … Harms of screening and treatment
There is inadequate direct evidence to determine the harms of … indirect evidence of harms associated with antibiotic use. … There is inadequate direct evidence to determine the harms of screening and treatment. … However, based on the known harms associated with antibiotic use, the overall harms can be bounded as
-
www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-xi-tool-assess-adequacy-and-certainty-evidence-task-force-recommendation
July 01, 2017 - , or cannot be determined )
( substantial, moderate, small, zero, or cannot be determined )
Harms … What are the harms of screening for this disorder?
KQ 5. … What are the harms of early treatment for this disorder? … Coherence
( convincing, adequate, or inadequate )
( convincing, adequate, or inadequate )
Harms … or low )
( high, moderate, or low )
Magnitude of Net Benefit
( Net Benefit = Benefits – Harms