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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nq6dYEj2eZxLhVhBrWCD-j
July 01, 2024 - , the Task Force concluded that the evidence is insufficient to
assess the balance of benefits and harms … The Task Force identified evidence gaps and the need for more
research on:
• the benefits and harms … • the effect of screening on the incidence of bladder cancer and subsequent treatments; and
• the harms … bladder cancer in
asymptomatic populations; outcomes of treatment for screen-detected bladder cancer; or harms
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/weight-management-children-adolescents-interventions
February 10, 2022 - Are there harms associated with weight management interventions for children and adolescents? … Are there harms associated with labeling children and adolescents as overweight or obese? … What are the harms of stigma and anti-fat bias? … Are there long-term harms of weight loss attempts during childhood or adolescence (e.g., future weight … Serious harms are events resulting in death, hospitalization, or the need for urgent medical treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/high-body-mass-index-children-adolescents-interventions
February 10, 2022 - Are there harms associated with weight management interventions for children and adolescents? … Are there harms associated with labeling children and adolescents as overweight or obese? … What are the harms of stigma and anti-fat bias? … Are there long-term harms of weight loss attempts during childhood or adolescence (e.g., future weight … Serious harms are events resulting in death, hospitalization, or the need for urgent medical treatment
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening-prevent-fractures
November 18, 2021 - What are the harms of screening for fracture risk or osteoporosis? 4. … What are the harms associated with selected FDA-approved medications? … Screening Comparators
KQs 1, 3 (Screening benefits and harms):
No screening. … KQ 3 (Screening harms):
Overdiagnosis. … KQ 5 (Treatment harms):
Total adverse events.
Total serious adverse events.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/osteoporosis-screening
November 18, 2021 - What are the harms of screening for fracture risk or osteoporosis? 4. … What are the harms associated with selected FDA-approved medications? … Screening Comparators
KQs 1, 3 (Screening benefits and harms):
No screening. … KQ 3 (Screening harms):
Overdiagnosis. … KQ 5 (Treatment harms):
Total adverse events.
Total serious adverse events.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/tpsQcTR2sDok_YELXgBHFb
July 23, 2024 - of participants eligible for the
intervention, when paired with ‘at-risk’ terminology, may
cause harms … might
benefit from supportive interventions while also
limiting racial and socioeconomic bias and harms … Potential harms of child
maltreatment interventions
“Rates of harms, including those arising from … ethnic populations of interest will be important to
document in future trials.”1
How can potential harms … characterized (i.e.,
arising from surveillance or reporting bias), and
specifically how can rates of harms
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZgcL6cF6JsFzwRRhaSnqc9
December 01, 2022 - term benefits compared with
best medical therapy alone in historic trials but can result in
surgical harms … 2
What are the harms associated with revascularization of asymptomatic carotid artery stenosis? … 3
Harms of
screening
2
Harms of
intervention
4
Asymptomatic
adults
Mortality
Stroke
Quality of … The 2 trials, 2 national data sets, and 3 surgical regis-
tries reported procedural harms associated … of screening No studies examined direct harms
of screening
Stroke after angiography: 0.4%
and 1.2%
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-in-adults-screening
August 15, 2011 - There is inadequate evidence on harms of screening for bladder cancer. … harms from cystoscopy and biopsy, harms from labeling and unnecessary treatments, and overdiagnosis. … harms from cystoscopy and biopsy, harms from labeling or unnecessary treatments (such as transurethral … screening tests, and the benefits and harms of treatment. … Potential Harms of Screening and Treatment
The USPSTF found inadequate evidence on the harms associated
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan95/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
September 18, 2014 - During screening, persons may also experience harms. … What are the harms of screening (e.g., labeling and false-positive or false-negative results)? … from screening (e.g., labeling, false-negative or false-positive results and related harms, including … harms
Settings
Primary care and primary care–referable settings (e.g., correctional … because its harms are well-established.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan44/depression-in-adults-screening
July 03, 2014 - Do the harms vary by population characteristics * ? … What are the harms associated with primary care depression screening programs in pregnant and postpartum … Do the harms vary by population characteristics * ? … Do the harms vary by population characteristics * ? … What is the prevalence of other selected serious harms of treatment with antidepressants in the general
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/high-body-mass-index-children-adolescents-interventions
June 30, 2022 - Are there harms associated with weight management interventions for children and adolescents? … Are there harms associated with diagnosing children and adolescents as being overweight or having obesity … in the healthcare setting (e.g., harms associated with labeling)? … What are the harms of stigma and weight bias? What is the extent of weight bias in healthcare? … Are there long-term harms of weight loss attempts during childhood or adolescence?
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-children-and-adolescents-screening
June 30, 2022 - Are there harms associated with weight management interventions for children and adolescents? … Are there harms associated with diagnosing children and adolescents as being overweight or having obesity … in the healthcare setting (e.g., harms associated with labeling)? … What are the harms of stigma and weight bias? What is the extent of weight bias in healthcare? … Are there long-term harms of weight loss attempts during childhood or adolescence?
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lynch-syndrome-related-cancer-adults-risk-assessment-genetic-counseling-testing
February 02, 2023 - What are the harms associated with use of risk assessment tools for Lynch syndrome? 3b. … What are the harms associated with genetic testing for pathogenic variants associated with Lynch syndrome … For adults with Lynch syndrome, what are the harms associated with preventive interventions? … testing for Lynch syndrome–related cancer) improve patient knowledge, understanding of benefits and harms … of persons at risk for Lynch syndrome as well as investigate potential differences in benefits and harms
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/task-force-resources/uspstf-and-cost-considerations
April 01, 2021 - evidence related to cost-effectiveness, it excludes costs from its determination of the benefits and harms … available evidence on a particular clinical preventive service, assessing both the potential benefits and harms … Benefits and Harms Assessment in Determining Recommendation Grades
Recommendation grades are based … on the quality and strength of the available evidence about the potential benefits and harms of the preventive … service, as well as the size of the potential benefits and harms.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Fbj5RkuC7VEsKFULEsfwUg
January 01, 2016 - The final recommendations
summarize what the Task Force learned about the
potential benefits and harms … The best balance of benefits and harms
happens when screening is done every 2 years. (2)
The decision … Mammograms also have potential harms. The most serious potential harm is overdiagnosis. … The best balance of benefits and harms occurs when
screening is done every 2 years. … They are also
based on the size of the potential benefits and harms.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/qgddtkA8z3fg5PpZmjohVV
May 09, 2022 - Potential harms of screening questionnaires include screening results that show depression or anxiety … Counseling for these conditions is likely to have minimal harms. … There are some harms associated with medications, so youth
who are prescribed medications should be … However,
there is limited evidence of the benefits and harms of screening for suicide risk in people … They are also based on the size of the potential benefits and harms.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lung-cancer-screening1
May 03, 2018 - for identifying adults at higher risk of lung cancer mortality improve the balance of benefits and harms … What are the harms associated with screening for lung cancer with CT?
b. … What are the harms associated with workup or surveillance of nodules detected by screening?
b. … What are the harms associated with surgical resection of early (stage I) non-small cell lung cancer? … leading to additional tests and subsequent harms, and harms of workup (e.g., adverse events from biopsy
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8odDCN4Y3Y7fWy9256z4U5
November 21, 2022 - Potential Benefits and Harms of Screening for Skin Cancer
The goal of screening would be to identify … There is also not enough evidence to determine if there are harms associated with screening adolescents … Potential harms of screening include worry or stress from the screening process and
overdiagnosis. … Potential harms of treatment could include cosmetic harms, such as scarring from surgery, and
overtreatment … It is also based on the size of the potential
benefits and harms.
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www.uspreventiveservicestaskforce.org/uspstf/procedure-manual/procedure-manual-appendix-xi-tool-assess-adequacy-and-certainty-evidence-task-force-recommendation
July 01, 2017 - zero, or cannot be determined )
( substantial, moderate, small, zero, or cannot be determined )
Harms … What are the harms of screening for this disorder?
KQ 5. … What are the harms of early treatment for this disorder? … convincing, adequate, or inadequate )
KQ 3:
KQ 5:
( convincing, adequate, or inadequate )
Harms … Linkage Coherence
( convincing, adequate, or inadequate )
( convincing, adequate, or inadequate )
Harms
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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-xi-tool-assess-adequacy-and-certainty-evidence-task-force-recommendation
July 01, 2017 - , or cannot be determined )
( substantial, moderate, small, zero, or cannot be determined )
Harms … What are the harms of screening for this disorder?
KQ 5. … What are the harms of early treatment for this disorder? … Coherence
( convincing, adequate, or inadequate )
( convincing, adequate, or inadequate )
Harms … or low )
( high, moderate, or low )
Magnitude of Net Benefit
( Net Benefit = Benefits – Harms