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Showing results for "harms".

81. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
    January 01, 2008 - professional association Nomination Summary: The nominator is interested in the benefits and harms … What are the benefits and harms of treating patients with subclinical hypothyroidism vs. watchful waiting … What are the potential harms from treatment and non-treatment? … What are the harms of screening? 4. … What are the harms of treatment of sub-clinical hypothyroidism and sub-clinical hyperthyroidism?

82. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
    January 01, 2010 - Nomination Summary: The nominator is interested in the comparative maternal and fetal benefits and harms … For pregnant women or women receiving preconception care with depression, what are the comparative harms … Potential harms and benefits of depression treatment must be weighed against the potential harms of … an evidence-based product for clinicians and patients that addresses the comparative benefits and harms

83. Key Questions: Nonpharmacologic Treatment of Mental Health Conditions in Pregnant and Postpartum People (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kq-mental-health-pregnant.pdf
    January 01, 2021 - What is the effectiveness and comparative effectiveness and harms of non-pharmacologic treatments for … What is the effectiveness and harms of non-pharmacologic treatments compared with pharmacologic treatment … adherence to treatment, maternal clinical outcomes, fetal/neonatal/pediatric clinical outcomes Harms … adherence to treatment, maternal clinical outcomes, fetal/neonatal/pediatric clinical outcomes Harms … KQ1: Placebo, no treatment, Other non-pharmacological treatments KQ2: Pharmacologic treatment Harms

84. Accelerated Partial Breast Irradiation for Breast Cancer | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/accelerated-partial-breast-irradiation/key-questions
    April 14, 2021 - and proton radiation therapy, intra-operative radiotherapy) on ipsilateral breast cancer outcomes, harms … Breast cancer recurrence; short and long-term harms (e.g., Radiation Therapy Oncology Group scores and … Breast cancer recurrence, short- and long-term harms (e.g., Radiation Therapy Oncology Group scores and … Cavity visualization score, harms. … Cosmesis, treatment toxicities, other short- and long-term harms (e.g., Radiation Therapy Oncology Group

85. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
    July 01, 2023 - What is the frequency and severity of harms addressed by the patient and family engagement PSPs? … What measures or indicators have been used to examine the harms associated with the target of the patient … What patient and family engagement PSPs have been used to prevent, report, or mitigate harms to patients … for the patient and family engagement PSPs that have been used to prevent, report or mitigate the harms … What is the frequency and severity of harms addressed by the patient and family engagement PSPs?

86. CER 218 Evidence Summary: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
    April 01, 2019 - Long-term oral hormone therapies reduce hip and clinical fractures but increase multiple serious harms … long-term denosumab, risedronate, ibandronate, teriparatide, and abaloparatide on fractures and harms … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment (continued) Harms Due to … Fifth, reporting on harms was sparse and inconsistent between studies, limiting confidence around harms … Future studies should systematically collect, analyze and report harms data.

87. CER 218 Evidence Summary: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
    April 01, 2019 - • Long-term oral hormone therapies reduce hip and clinical fractures but increase multiple serious harms … of long-term denosumab, risedronate, ibandronate, teriparatide, and abaloparatide on fractures and harms … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment (continued) Harms Due to … Fifth, reporting on harms was sparse and inconsistent between studies, limiting confidence around harms … Future studies should systematically collect, analyze and report harms data.

88. Diagnosis and Treatment of Obsessive-Compulsive Disorder in Children and Adolescents (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/OCD-key-questions.pdf
    January 01, 2022 - KQ2: What are the comparative effectiveness and harms of psychological, pharmacological, and neuromodulation … KQ3: What are the comparative effectiveness and harms of complementary/integrative treatments, such … KQ4: What are the comparative effectiveness and harms of the different care settings and care intensities … PICOTS for KQ2: What are the comparative effectiveness and harms of psychological, pharmacological and … PICOTS for KQ4: What are the comparative effectiveness and harms of the different care settings and

89. Infantile-Hemangioma Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
    January 01, 2016 - We considered 14 of these as good quality for harms reporting, 3 as fair quality for harms reporting … The studies did not address harms. KQ2. … any harms. … Surgical harms included wound dehiscence. … Topical timolol RCT: 1 (41) Cohort studies: 4 (287) Case series: 1 (25) Lack of harms Low No harms

90. Acute Treatments for Episodic Migraine | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/migraine-treatments/protocol
    January 08, 2020 - harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … including gastrointestinal-related harms, cardiovascular-related harms, kidney-related harms, falls, … fractures, motor vehicle accidents, endocrinological harms, infections, cognitive harms, and psychological … harms (e.g., depression)? … Misuse, opioid use disorder, overdose and other harms KQ 2.

91. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - Congress, was to evaluate the evidence on benefits and harms of cannabinoids and similar plant-based … • Longitudinal studies on opioids to evaluate longer-term outcomes, including associated harms … • Longitudinal outcome studies on opioids, including harms (e.g., refractory opioid dependence, … • Although evidence was limited, serious harms were not reported for either program. … • Systematic reviews of harms (regardless of indication) report that acetaminophen, prednisolone

92. Opioid Treatments for Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/opioids-chronic-pain/protocol
    February 27, 2019 - ; some harms (including overdose risk) were dose-dependent. … Harms and Adverse Events a. … harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … (including overdose, substance use disorder and misuse; other harms (including gastrointestinal harms … , cognitive harms, and psychological harms, including depression and suicidality).

93. Topic Brief on Mental Health Treatments in Pregnancy (pdf file)
    effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-disposition-mental-health-pregnancy_0.pdf
    June 01, 2021 - • Which of these harms are most important to patients and providers? … and harms of interest to the nominators … This is especially true for harms of antidepressants, and specifically for SSRIs. … potential harms to the infant/fetus. … These harms must be balanced with the harms of not treating the mother. 2e.

94. Ankyloglossia Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - , and Children Through Age 18 In order to identify all possible harms, we sought harms from all comparative … for harms, either reporting actual harms or specifically indicating that they found none. … Most studies that reported harms information explicitly noted that no significant harms were observed … (n = 17) or reported minimal harms. … Eighteen studies reported that no significant harms were observed.

95. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - /doi.org/10.23970/AHRQEPCCER215 Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms … Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms/research Published Online: March … Data on harms of trazodone may still be relevant to clinicians but it is not likely to be used as a … because we lack comparative harms evidence. … In this report little data were available for specific harms.

96. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - /doi.org/10.23970/AHRQEPCCER215 Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms … Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms/research Published Online: March … Data on harms of trazodone may still be relevant to clinicians but it is not likely to be used as a … because we lack comparative harms evidence. … In this report little data were available for specific harms.

97. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - • Harms reporting was limited by sample sizes and short followup duration though most studies did … not find frequent serious harms. … to treatment, or the benefits or harms of endometrial surveillance for patients using hormonal therapies … examined the evidence for Key Questions related to GSM screening (KQ1), treatment effectiveness and harms … but serious harms, though most studies did not find evidence of frequent serious harms.

98. Disposition of Comments: Comparative Effectiveness Review No. 234_Management of Primary Headaches in Pregnancy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-234-headaches-pregnancy-comments.pdf
    November 12, 2020 - The EPC had inadvertently excluded a systematic review of indomethacin and its harms in pregnant women … overall, and paucity of studies in postpartum and breastfeeding women), contextual issues, and known harms … Reviewers suggested reorganizing the report such that the direct evidence (primary studies of benefits and harms … ) and indirect evidence (systematic reviews of harms) appear together in the same section for each intervention

99. Comparative Effectiveness of Therapies for Children With Autism Spectrum Disorder | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/autism-update/clinician
    September 23, 2014 - Key Clinical Issue What evidence is available regarding the effectiveness, benefits, and harms of therapies … For many other interventions, the evidence is insufficient to permit an estimate of their benefits or harms … This does not mean that these interventions are not associated with benefits or harms but that further … [evidence insufficient] Harms Aripiprazole and risperidone are associated with significant weight … Whether there are any harms associated with behavioral, educational, allied health, or CAM interventions

100. Terbutaline Pump for the Prevention of Preterm Birth | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research
     September 29, 2011 - Objectives To compare the benefits and harms of the SQ terbutaline pump with other tocolytics, conservative … We included noncomparative studies only for pump-related harms. … Absent or inconclusive evidence addressed all other neonatal health outcomes, neonatal harms, maternal … harms, and pump-related outcomes. … While postmarketing surveillance has detected cases of serious harms, safety of the therapy remains unclear