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effectivehealthcare.ahrq.gov/sites/default/files/han.pdf
December 26, 2012 - o Benefits and harms of communicating uncertainty in clinical practice
Slide 5: Uncertainty
• Main … Communicating
uncertainty in clinical evidence:
ethical
problems
• Patient autonomy
• Benefits and harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
April 01, 2016 - studies, which may lead to followup interventions that are not beneficial and may
be associated with harms … could lead to subsequent interventions that might not be benefi-
cial and that might be associated with harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
August 07, 2012 - despite recent practice guidelines and systematic
reviews,6, 10, 13-19 the comparative benefits and harms … Additionally, the
reviewed studies found evidence of increased side effects and harms with the use of … The harms and benefits of tympanostomy tubes for managing OME in children have been addressed
by two … KQ 3: What are the differences in harms or tolerability among the different treatment options? … Harms: all reported harms for each treatment option will be included.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - KQ 2: What are the benefits and harms of amniotomy in women in spontaneous labor? … KQ 4: What are the benefits and harms of epidural analgesia in labor, particularly in
terms of the risk … 5: How does the frequency of cervical examination affect the probability of specific
benefits and harms … KQ 7: For women with abnormal labor, what are the relative benefits and harms of high-
vs. low-dose … Benefits and harms of breast cancer
screening: a systematic review. JAMA (In press).
28.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - Potential harms include increased physical
harm to the patient (severe and even fatal side effects,15 … Because of safety concerns in relation to aggressive behavior, our harms outcomes
are more inclusive … Also, we note that harms to staff and/or patient might come from the
use of seclusion or restraints … KQ 2: Regarding harms for adult psychiatric patients in acute care settings:
a. … For those with active aggression, what are the comparative harms of strategies,
including seclusion
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
March 21, 2013 - These
tables are not intended to provide global
summary judgments of the relative benefits
and harms … We have deleted the reference to
dydrogesterone in the discussion on harms
but have retained it when … Medical Eligibility
Criteria for Contraceptive Use, 201 from CDC
MMWR as a source for harms data. … which we did identify
trials (or trial arms) and lastly we summarize
for the class of agents the harms … of the
literature and rather than attempting to group
as major and minor, have described all the
harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - In patients with acute gout, what are the benefits and
harms of different pharmacological therapies? … Does effectiveness (benefits and harms) differ
according to patient baseline demographic
characteristics … Does effectiveness (benefits and harms) differ
according to disease severity, including initial clinical … In adults with gout, what are the benefits and harms of
different dietary therapies and life style measures … In patients with acute gout, what are the benefits
and harms of different pharmacological therapies?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0368_11-08-2010.pdf
January 01, 2010 - mindfulness-based strategies
are becoming increasingly available, the balance of efficacy and potential harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0430_04-22-2011.pdf
January 01, 2011 - of recatheterization, prevention
of urinary tract infections, improved quality of life, potential harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0440_06-01-2011.pdf
January 01, 2011 - Harms: Earlier initiation of treatment for cancer progression that does not increase
survival (thereby
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
April 01, 2012 - It is
the balance of the benefits and harms that needs to be
better evaluated. … This would require that such harms be reported with
enough detail to do so. … If the included studies were to
report harms in a more systematic fashion, this might be
possible. … This would require that such harms be reported with
enough detail to do so. … Comparison of differential harms of medical versus
surgical treatment would require that those harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - What are the potential harms in women of:
a. PCI vs. fibrinolysis/supportive therapy with STEMI? … CABG in women with stable or unstable angina
4
What are the potential harms in women of PCI vs. … 1
What are the potential harms in women of PCI vs. fibrinolysis/supportive therapy with STEMI? … What are the potential harms in women of PCI vs. … 1
What are the potential harms in women of PCI vs. fibrinolysis/supportive therapy
with STEMI?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
January 01, 2010 - compared to the harms of no
screening/limited screening. … This CER evaluated the harms of screening for
MRSA-carriage compared to the harms of not
screening … the
harms of not screening, and the harms of
screening limited populations compared to the
harms … An
evaluation of the harms of screening (without a
comparison of the harms of not screening) was
outside … , understanding the comparative harms of
screening for MRSA carriage is important.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
June 10, 2013 - An assessment of the effectiveness and harms of transitional care
interventions is needed to support … Potential harms or unintended consequences of
interventions do not appear to have been widely considered … Question 5
Do transitional care interventions differ in effectiveness or harms for subgroups of patients … health outcomes (KQ 2), rather than asking about the same outcomes in a separate question
devoted to harms … strength of
the body of evidence to answer the KQs on the comparative effectiveness, efficacy, and harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
September 13, 2011 - or dose reduction, which is
usually based on a medical plan or a desire to avoid treatment-related harms … Question 4
What are the harms associated with hepatitis C antiviral treatment adherence interventions … of HCV
• Adverse Effects
○ Paradoxical decrease in adherence
○ Increase in treatment-related harms … Treatment
Adherence
Interventions
Adults undergoing
antiviral therapy
Treatment
Adherence
Harms … In addition, the quality assessment of adverse effects and harms data will be
informed by the Methods
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
August 17, 2011 - Question 2
What harms result from public reporting?
B. … Harms include any negative consequence or adverse events for any members of
the populations listed … Examples of harms could include:
a. … These negative changes could result in
harms. … Analytic framework
Harms
(e.g ., reduced access to services
for patients or misclassification
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
July 01, 2011 - Reviews are systematic reviews of existing research on the effectiveness,
comparative effectiveness, and harms … topic, beyond the effectiveness of a single
intervention, by comparing the relative benefits and harms … Identifying new
evidence on harms warrants at least the same rigor in surveillance search as that for … searched for new studies reporting adverse events or SRs, meta-analyses
and HTA reports focusing on harms … need for updating now) were based on changes in
four indicators: (a) evidence on the benefits and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - populations were studied, the detailed components of the treatment program, and the
health outcomes and harms … What are the potential safety issues and harms that may be associated with an MPP? … Potential Safety Issues or Harms
E. … Potential Safety Issues or Harms
Study Safety Issues or
Harms Assessed MPP Therapy Comparison
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Key Question
Key Question: What are the comparative benefits and
harms of different contrast media in … How do benefits or harms of contrast media differ by
patient characteristics (known risk factors such … How do benefits or harms differ by the
dose of contrast medium (i.e., by volume of dose and
number … How do benefits or harms of contrast media differ
according to the type of preventive strategy used? … We did not
find any studies that examined whether the benefits or
harms of contrast media differed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - What are the harms associated with prevention strategies?
c. … Question 3: What is the comparative effectiveness and harms of different antibiotic treatments?
a. … Question 4: What are the effectiveness and harms of non-antibiotic adjunctive interventions?
a. … environmental
cultures
Days to resolution of
diarrhea (choice of faster
working treatment)
Harms … Treatment of false
positives
Increased
resistance
Isolation harms
Prevention
Patient Specific