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Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf

October 01, 2021 - in a clear and concise way, in order to facilitate judgments of the overall balance of benefits and harms … In addition, dot plots do not need to be restricted to harms and also could be adapted to summarize … Our tool could be used for outcomes that are benefits as well as harms. … We created a Stata module to produce dot plots from pooled data for multiple outcomes (benefits or harms

Venous-Ulcers-Treatment-Future Research (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf

January 01, 2014 - For patients with chronic venous leg ulcers, what are the benefits and harms of using dressings that … For patients with chronic venous leg ulcers, what are the benefits and harms of surgical procedures … For patients with chronic venous leg ulcers, what are the benefits and harms of surgical procedures … Insufficient 3c What are the relative benefits and harms of different surgical interventions? … …for reporting harms. 1. Listed by category, not according to previous rankings.

Psoriasis-Chronic Executive (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf

November 01, 2012 - Questions The objective of this comparative effectiveness review (CER) is to examine the benefits and harms … All three classes of therapy are associated with known harms that are clearly defined within clinical … practice guidelines.4,8,32 Some harms such as changes in weight or the lipid profile may surface in … Unfortunately, the longest followup period among included studies in which harms were reported was … A similar opportunity arises with harms, as even in the current literature base harms were rarely evaluated

Treatments for Schizophrenia in Adults: A Systematic (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf

January 01, 2017 - For studies specifically on harms of antipsychotic drugs, populations can be mixed-diagnoses, as the … harms are not diagnosis- specific 2. … How do the benefits and harms of psychosocial and other nonpharmacological treatments for adults with … Harms Outcomes Overall rates of patients reporting adverse events were 11 to 20 percent higher with … Harms Outcomes Four trials and seven systematic reviews assessed or reported any type of harms associated

Appendicitis Executive (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf

December 01, 2015 - Key Question 3: What are the harms of diagnostic tests per se, and what are the treatment-related harms … For Key Question 3, we considered adverse effects, including direct harms of testing and harms of test-directed … Key Question 3: What are the harms of diagnostic tests per se, and what are the treatment-related … The fact that so few studies reported harms raises concerns about selective outcome reporting. … Adverse Events of Testing Information on harms was often incomplete and poorly reported.

Urinary-Incontinence-Treatment Executive (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf

April 01, 2012 - We analyzed harms regardless of how authors perceived the causality of treatments. … The methods to assess harms were not assessed for validity. … Weight loss and exercise improved UI in obese women without evident harms. … Which factors are associated with differences in harms remains unclear. … Benefits and harms with drugs did not differ by individual quality criteria.

Effective Health Care (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0107_05-19-2009.pdf

January 01, 2009 - Potential harms will also be important to address.

VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf

January 30, 2014 - We added a separate Key Question for harms and adverse effects associated with interventions. … Harms will be collected from the studies included for effectiveness, plus cohort studies if only RCTs … The review will identify and analyze the evidence for harms of pharmacologic interventions used to … We will extract harms data reported in the grey literature, including integrated safety reports from … Potential adverse effects / harms of pharmacologic interventions include: • Metabolic effects: weight

Evidence-based Practice Center Systematic Review Protocol (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf

May 14, 2010 - sustaining a fracture during the follow-up period) (c) KQ4: What are the short- and long-term harms … (when used specifically to treat or prevent low bone density/osteoporotic fracture), and do these harms … • Outcomes: - Any reported harms/adverse events (AEs) that can be directly associated with use … - Studies that report harms but that do not report fracture risk as an outcome will also be considered … Assessing harms when comparing medical interventions.

Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf

February 01, 2018 - Systematic Reviews Methods Guide www.ahrq.gov Presenter Presentation Notes Prioritization and Selection of Harms … for Inclusion in Systematic Reviews This presentation entitled: Prioritization and Selection of Harms … Prioritization and Selection of Harms for Inclusion in Systematic Reviews.

Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf

February 01, 2018 - Systematic Reviews Methods Guide www.ahrq.gov Presenter Presentation Notes Prioritization and Selection of Harms … for Inclusion in Systematic Reviews This presentation entitled: Prioritization and Selection of Harms … Prioritization and Selection of Harms for Inclusion in Systematic Reviews.

Management of suspected opioid overdose with Naloxone by Emergency Medical Services personnel (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf

November 29, 2016 - naloxone in the out-of-hospital setting from EMS personnel, what are the comparative benefits and harms … do not improve after an initial dose of intranasal naloxone), what are the effects on benefits and harms … are alert and oriented after naloxone administration by EMS personnel, what are the benefits and harms … hospital admission, cost to the EMS agency for providing treatment); and adverse effects and other harms … for providing treatment Naloxone Administration** KQs 1, 2*** No transfer to hospital Harms

Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)

effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf

May 09, 2016 - The Key Questions Key Question 1a: What are the benefits and harms of pharmacologic treatment options … Key Question 1b: What are the benefits and harms of non-pharmacologic treatment options (foot care, … Key Question 2a: What are the benefits and harms of pharmacologic treatment options to improve the symptoms … Key Question 2b: What are the benefits and harms of non-pharmacologic treatment options (alpha-lipoic … • Harms (KQ2a and KQ2b): Adverse effects reported in >10% of patients and all dropouts [10% is generally