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Showing results for "harms".

41. Executive Summary_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
    May 01, 2025 - • We only found one study reporting on potential harms from multicancer screening tests. … We graded the strength of evidence as insufficient for harms based on this single study. … This systematic review looks at whether MCSTs work, how accurate they are, and what harms they might … KQ 4: What are the harms of screening with MCSTs? … We only found one study that looked at potential harms.

42. Quantitative Synthesis II: Interactive Quiz (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
    May 29, 2025 - studies Cohort and case-control studies What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort

43. Quantitative Synthesis II: Interactive Quiz (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
    May 29, 2025 - studies Cohort and case-control studies What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort

44. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0355_09-22-2010.pdf
    January 01, 2010 - Anonymous individual Nomination Summary: The nominator questions the comparative effectiveness and harms … to another insomnia intervention Outcome(s): Quality of life, sleep quality, fatigue, and harms … For patients with insomnia, how do commonly used medications compare for effectiveness and harms, including … Insomnia can be associated with various harms, including decreased quality of life, cognitive deficits … A review on this topic will help to compare the relative benefits and harms of these interventions.

45. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … including gastrointestinal-related harms, cardiovascular-related harms, kidney-related harms, falls … , fractures, motor vehicle accidents, endocrinological harms, infections, cognitive harms, and psychological … harms (e.g., depression)? … Misuse, opioid use disorder, overdose and other harms KQ 2.

46. CER 218 Evidence Summary: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
    April 01, 2019 - • Long-term oral hormone therapies reduce hip and clinical fractures but increase multiple serious harms … of long-term denosumab, risedronate, ibandronate, teriparatide, and abaloparatide on fractures and harms … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment (continued) Harms Due to … Fifth, reporting on harms was sparse and inconsistent between studies, limiting confidence around harms … Future studies should systematically collect, analyze and report harms data.

47. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
    March 28, 2019 - /doi.org/10.23970/AHRQEPCCER215 Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms … Source: https://effectivehealthcare.ahrq.gov/topics/depression-harms/research Published Online: March … Data on harms of trazodone may still be relevant to clinicians but it is not likely to be used as a … because we lack comparative harms evidence. … In this report little data were available for specific harms.

48. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - Congress, was to evaluate the evidence on benefits and harms of cannabinoids and similar plant-based … • Longitudinal studies on opioids to evaluate longer-term outcomes, including associated harms … • Longitudinal outcome studies on opioids, including harms (e.g., refractory opioid dependence, … • Although evidence was limited, serious harms were not reported for either program. … • Systematic reviews of harms (regardless of indication) report that acetaminophen, prednisolone

49. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
    July 01, 2024 - • Harms reporting was limited by sample sizes and short followup duration though most studies did … not find frequent serious harms. … to treatment, or the benefits or harms of endometrial surveillance for patients using hormonal therapies … examined the evidence for Key Questions related to GSM screening (KQ1), treatment effectiveness and harms … but serious harms, though most studies did not find evidence of frequent serious harms.

50. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
    July 01, 2023 - What is the frequency and severity of harms addressed by the patient and family engagement PSPs? … What measures or indicators have been used to examine the harms associated with the target of the patient … What patient and family engagement PSPs have been used to prevent, report, or mitigate harms to patients … for the patient and family engagement PSPs that have been used to prevent, report or mitigate the harms … What is the frequency and severity of harms addressed by the patient and family engagement PSPs?

51. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
    October 05, 2018 - Osteoporosis treatment harms vary by drug class. … >100 subjects for rare harms and >1000 subjects for other harms KQ 5: Effect of drug treatment … Timing Setting Study Design KQ 7: Harms of drug treatment holidays KQ8: Predictors of harms … >100 subjects for rare harms and >1000 for other harms Abbreviations: ALP = alkaline phosphatase … ) • Harms (Serious adverse events and specific harms as listed in Table 2) Outcome predictors (

52. App-F2-Surv-Report-2-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time … Harms of lidocaine patch versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk

53. Infantile-Hemangioma Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
    January 01, 2016 - We considered 14 of these as good quality for harms reporting, 3 as fair quality for harms reporting … The studies did not address harms. KQ2. … any harms. … Surgical harms included wound dehiscence. … Topical timolol RCT: 1 (41) Cohort studies: 4 (287) Case series: 1 (25) Lack of harms Low No harms

54. Disposition of Comments_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
    May 14, 2025 - “We included two different key questions related to harms. … Regarding the noted harms of tests: harms should also be distinguished by frequency and severity. … Harms. … ,” rather than just harms. … In the list of harms that follow, the authors group all possible harms without consideration of their

55. Disposition of Comments for Comparative Effectiveness Review No. 240: Treatments for Acute Pain: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-revised-comments.pdf
    December 29, 2020 - The report summarizes evidence on benefits as well as harms of NSAIDs. … The review summarized evidence on benefits as well as harms of NSAIDs. … Harms of opioids are well-described in the report. … Potential harms of opioids are described in the Background section. … This report focuses on benefits and harms of treatment for acute pain.

56. Ankyloglossia Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
    May 01, 2015 - , and Children Through Age 18 In order to identify all possible harms, we sought harms from all comparative … for harms, either reporting actual harms or specifically indicating that they found none. … Most studies that reported harms information explicitly noted that no significant harms were observed … (n = 17) or reported minimal harms. … Eighteen studies reported that no significant harms were observed.

57. Kidney-Disease-Medicine Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
    January 01, 2012 - KQ4: Monitoring Harms KQ6: Treatment Harms Asymptomatic adults •With CKD risk factors •Without … Take into account potential screening harms. … increases harms. … Take into account potential monitoring harms. Key Question 4. … for worsening kidney function or damage increases harms.

58. Update Topic CER 31 Clostridium difficile NSD FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - (b) What are the harms associated with prevention strategies? … characteristics § Resistance of other pathogens Key Question 4: What are the effectiveness and harms … § What are the harms associated with prevention strategies? … What are the comparative effectiveness and harms of different antibiotic treatments? … What are the effectiveness and harms of nonstandard adjunctive interventions?

59. Disposition of Comments: CER 224, Treatment of Depression in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
    April 10, 2020 - on harms. … on harms. … on harms. … profound harms of untreated depression. … on harms.”

60. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
    January 01, 2010 - Nomination Summary: The nominator is interested in the comparative maternal and fetal benefits and harms … For pregnant women or women receiving preconception care with depression, what are the comparative harms … Potential harms and benefits of depression treatment must be weighed against the potential harms of … an evidence-based product for clinicians and patients that addresses the comparative benefits and harms