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Showing results for "harms".

381. Refining Key Questions: Interactive Case Study Quiz
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
     May 01, 2010 - ; and (2) What are the benefits and harms of using rFVIIa for selected off-label indications in patients … Current evidence of low strength is too limited to compare harms and benefits.   … Current evidence of low strength is too limited to compare harms and benefits.   … Current evidence is insufficient for comparing the harms and benefits of rFVIIa use in infant patients … Current evidence is insufficient for comparing the harms and benefits of rFVIIa use in prostatectomy.

382. Refining Key Questions: Interactive Case Study Quiz
     effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
     May 01, 2010 - ; and (2) What are the benefits and harms of using rFVIIa for selected off-label indications in patients … Current evidence of low strength is too limited to compare harms and benefits.   … Current evidence of low strength is too limited to compare harms and benefits.   … Current evidence is insufficient for comparing the harms and benefits of rFVIIa use in infant patients … Current evidence is insufficient for comparing the harms and benefits of rFVIIa use in prostatectomy.

383. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
     December 16, 2011 - patients receiving treatment compared to patients receiving routine prenatal care. 3,15 Potential harms … test properties of screening and diagnostic tests for GDM; b) evaluate the potential benefits and harms … duration of followup  Settings: All settings KQ2: What is the direct evidence on the benefits and harms … insulin therapy, and oral hypoglycemic agents  Comparators: Placebo or no treatment  Outcomes: Harms … KQ5 addresses harms, including anxiety, healthcare system issues, burden on practitioner’s office,

384. Binge-Eating Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_research-protocol.pdf
     July 21, 2014 - KQ 2: What is the evidence for harms associated with treatments for binge eating disorder? … older) meeting criteria for LOC eating2 Interventions: Applies only to KQs on effectiveness and harms … life: health-related quality of life or patient-reported outcomes not otherwise listed above • Harms … Analytic framework for binge eating disorder and loss-of-control eating: Effectiveness and harms of … treatment harms, and costs (e.g., health care cost and use, lost work days).

385. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - KQ 3: What are the harms of diagnostic tests per se, and what are the treatment- related harms of … Direct harms of testing (e.g., harms from exposure to ionizing radiation, allergic reactions/kidney … of testing per se Test-directed treatment Harms of test directed treatment KQ#3# KQ#3# KQ#1a … (e.g., change in diagnostic thinking, impact on therapeutic decisionmaking, clinical outcomes, and harms … of testing; harms of test-directed treatment).

386. Autism-Adolescents Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
     August 01, 2012 - We also assessed the harms of interventions, defined by the Agency for Healthcare Research and Quality … Key Question 5: Among adolescents and young adults with ASD, what harms are associated with available … Finally, interventions may be associated with harms/adverse effects. … In addition to outcomes for treatment effectiveness and family outcomes, we extracted data on harms/ … Only studies of medical interventions addressed harms (Key Question 5).

387. Surveillance Report: Masks for Prevention of COVID-19 in Community and Healthcare Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
     July 17, 2020 - Harms Limited evidence of no difference in harms by mask type. … • No serious harms reported with N95 respirators and surgical masks in randomized controlled trials

388. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
     January 01, 2013 - What are the adverse effects or harms associated with the treatments guided by tests of iron status? … What are the adverse effects or harms associated with testing using newer and/or older markers of … , and most studies did not attribute harms to either testing or treatment. 1 Study Design Issues … o Most of the reported harms were attributed to iron therapy. Key Question 3. … • Incorporates issues around both clinical benefits and potential clinical harms.

389. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
     April 01, 2013 - What are the comparative harms associated with antiviral treatments? 3b. … What are the comparative harms associated with antiviral treatments? 3 3b. … What are the comparative harms associated with antiviral treatments? … Do these harms differ according to patient subgroup characteristics? … • Incorporates issues around both clinical benefits and potential clinical harms.

390. Point-Of-Care Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
     April 01, 2014 - Comparative benefits and harms of second-generation antidepressants in the pharmacologic treatment … Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review … Benefits and Harms of Treating Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis … Benefits and Harms of Treating Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis … Benefits and Harms of Treating Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis

391. Chronic-Kidney-Disease-Anemia-2011 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
     January 01, 2011 - What are the adverse effects or harms associated with testing using newer and/or older markers of iron … What are the adverse effects or harms associated with the treatments guided by tests of iron status? … on harms.23,26,35,40-43 Specifically, three studies reported no adverse events associated with iron … What are the adverse effects or harms associated with testing using newer and/or older markers of … – Most of the reported harms were attributed to iron therapy. Key Question 3.

392. Newer Medications for Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
     April 21, 2015 - approval of new drugs and the availability of new evidence for efficacy, comparative effectiveness, and harms … Question 2: What are the harms and comparative harms of newer medications for LUTS associated with … Question 3: Do the comparative benefits and harms of newer medications for LUTS associated with BPH … with LUTS associated with BPH Study Objective To test the efficacy, comparative effectiveness, and harms … Study Design • Efficacy/comparative effectiveness: RCTs Harms: RCTs and large observational studies

393. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
     July 01, 2012 - While rates of false positives and false negatives may be directly related to adverse effects or harms … and NPV, but if no such test is available, clinicians may be interested in the added benefits and harms … Tests that are more invasive will naturally have greater harms. … of false positives and false negatives when assessing the harms of a diagnostic test. … The degree of harms from false positives depends on the invasiveness of further testing or treatment

394. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
     June 15, 2010 - Rates of dropouts due to harms varied from 9 to 39 percent. … Question 2: What are the harms of each of the monotherapy or combined therapies among these adults and … How do the harms compare across different interventions? … Harms associated with any of these interventions are evaluated in KQ2 and can include suicide, sexual … Additionally, we will evaluate studies for adequacy of collecting and reporting harms using the McHarm

395. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - regular updating of research evidence.13,21 Researchers should be able to estimate the benefits and harms … Which patient characteristics are associated with the harms of examined physical therapy interventions … Do harms differ by the duration of the treatment and time of followup? … To assess harms of treatments we will follow the recommendations from the Methods Guide for Comparative … harms regardless of how authors perceived causality of treatments.

396. Trauma Informed Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-protocol.pdf
     April 19, 2023 - or models, and components to establish the state of the science of its effectiveness and potential harms … What is the evidence of benefits and/or harms of TIC on outcomes for patients/clients? ○ KQ 1a. … of TIC models, and organizational and practice characteristics, are associated with benefits and/or harms … What is the evidence of benefits and/or harms of TIC on outcomes for patients/clients? ○ KQ 2a. … engagement, trust, comfort or satisfaction, and strengths-based outcomes (e.g., quality of life) Harms

397. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
     September 18, 2012 - The identified harms will be characterized by using the Common Terminology Criteria for Adverse Events … McHarm, the tool was developed from quality rating items generated by a review of the literature on harms … • Was the mode of harms collection active (participants are asked about the occurrence of specific … • Did study specify who collected the harms data? • Did the study specify the timing of harms? … McMaster Quality Assessment Scale of Harms (McHarm) Quality Assessment Scale for Primary Studies.

398. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
     July 01, 2012 - explore the impact of uncertainty; make implicit assumptions clear; evaluate tradeoffs in benefits, harms … of treatment in true positive diagnoses, avoidance of harms of treatment in true negative diagnoses … However, in other cases, harms can be induced both by the treatment and the test (e.g., if the test is … Evidence exists to estimate the benefits and harms of pharmacologic therapy in those with and without … Decision- analytic modeling to evaluate benefits and harms of medical tests: uses and limitations.

399. Systematic Review on Treatments for Acute Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
     June 01, 2022 - The 2020 report addressed benefits and harms of opioid, nonopioid pharmacologic, and nonpharmacologic … pain conditions, the report addressed the effectiveness and comparative effectiveness (benefits and harms … harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … harms, cardiovascular- B-3 related harms, kidney-related harms, falls, fractures, motor vehicle … accidents, endocrinological harms, infections, cognitive harms, and psychological harms (e.g., depression

400. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/introduction-to-user-guide-overview.pptx
     January 01, 2013 - effectiveness research is the “generation and synthesis of evidence that compares the benefits and harms … effectiveness research is the “generation and synthesis of evidence that compares the benefits and harms … complex conditions) Can lead to overuse, underuse, and off-label/risky use (unknown balance of benefits/harms … have not been rigorously studied, which could be a risky gamble since the true balance of treatment harms