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Total Results: 1,494 records

Showing results for "harms".

341. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - effectiveness of treatments for menopausal symptoms, along with potential long-term benefits and harms … What are the significant agent-specific harms/adverse effects of nonhormone therapies? … symptomatic due to natural or surgically induced menopausea Hormone or Nonhormone Therapies Harms … Juxtaposing evidence concerning symptom relief (as obtained here) with models for the long-term harms … Estrogens are accompanied by potential long-term harms that require consideration.

342. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - A systematic review that outlines the benefits and harms of treatment options for major depressive disorder … This SR will focus on the benefits and harms of formal exercise activities that enroll people with an … KQ 3b: Do the risks of treatment harms vary by MDD severity? … KQ 4: Do the benefits and risks of harms of these treatment options differ by subgroups of patients … Comparative risk for harms of second- generation antidepressants: a systematic review and meta-analysis

343. Disposition of Comments for CER 168 Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
     January 15, 2016 - We agree that harms reported were typically associated with oral propranolol, and we have revised this … We included case series with at least 25 individuals for harms data only. … Peer reviewer #3 Results 5) When discussing harms of Laser therapy – must include potential dangers/ … Peer reviewer #3 Results 17) Regarding the Timolol studies, no harms were reported but most of these … We have noted this in the harms of beta-blockers section.

344. Colorectal-Cancer-Protocol_130520 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
     May 20, 2013 - The imaging modalities vary in their accuracy and in the harms they can potentially cause. … What are the adverse effects or harms associated with using imaging techniques, including harms of … What are the adverse effects or harms associated with using imaging techniques, including harms of … Harms. … will be used to address questions about harms and adverse events.

345. Evidence-Summary-CER-209-Noninvasive-Nonpharmacological-Treatment-For-Chronic-Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
     June 01, 2018 - • There was no evidence suggesting serious harms from any of the interventions studied; data on harms … Harms Although data on harms were limited, no evidence suggested serious harms for the interventions … interventions in risk of harms or withdrawals. … At the same time, there was no evidence suggesting serious harms, although data on harms were limited … be assessed (including harms).

346. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
     May 01, 2005 - The prespecification of 13 particular harms, however, may not be possible for all topics; in … Assessing the Risk of Bias for Harms Although harms are almost always included as an outcome in intervention … Harms are defined as the “totality of possible adverse consequences of any intervention, therapy or … the harms and benefits of the treatment. … Better reporting of harms in randomized trials: an extension of the CONSORT statement.

347. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - I disagree that harms of biopsy “appear to be small”. … The KQ simply reports harms associated with biopsy. … these harms do exist. … the harms of not screening for HCV. … the harms associated with not screening for HCV.

348. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - methotrexate, sulfasalazine).21 There were also no studies comparing efficacy, effectiveness, and harms … Finally, we will examine comparative effectiveness and harms of drug therapies in patient subgroups. … KQ 3: For patients with early RA, do drug therapies differ in harms, tolerability, patient adherence … studies (all KQs): any active intervention listed above For additional observational studies of harms … For studies of harms (i.e., overall [KQ 3] and among subgroups [KQ 4]), we will also include any other

349. Nonopioid Pharmacologic Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
     February 01, 2019 - and long-term effectiveness of opioids, there is a real need to fully understand the benefits and harms … Harms and Adverse Events a. … In patients with chronic pain, what are the risks of nonopioid pharmacologic agents for harms including … How do harms vary depending on: (1) the specific type or cause of pain, (2) patient demographics, (3 … We will evaluate the persistence of benefits or harms by evaluating the three periods identified in

350. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic … Summary of findings: rheumatoid arthritis Harms and strength Key comparisons Efficacy and strength … Summary of findings: rheumatoid arthritis (continued) Harms and strength Key comparisons Efficacy and … Summary of findings: rheumatoid arthritis (continued) Harms and strength Key comparisons Efficacy and … This 12-month study did not report any differences in harms between etanercept and infliximab.

351. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
     February 23, 2012 - Key Question 2: What evidence is available about the harms related to quality improvement strategies … Harms of the intervention to the individual patients or the health care system will be captured if they … Adverse outcomes or harms resulting from a quality improvement intervention are also illustrated. … o Outcomes (including harms) related to quality improvement strategies that address disparities. … Harms of the intervention are represented within an oval with an attached box for key question 2: “

352. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
     August 05, 2010 - What are the comparative benefits and harms of treating osteoarthritis with oral medications or supplements … How do these benefits and harms change with dosage and duration of treatment? c. … Evidence of harms associated with the use of nonsteroidal antiinflammatory drugs (NSAIDs) includes studies … Question 2 Do the comparative benefits and harms of oral treatments for osteoarthritis vary for certain … Question 4 What are the comparative benefits and harms of treating osteoarthritis with oral medications

353. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 -  Are the decisional dilemmas centered on efficacy, effectiveness, or harms? … First, RCTs may be underpowered to detect differences between comparators in harms. … small and/or of too short duration for uncommon harms or longer-term harms to be detected. … o Are the decisional dilemmas centered on efficacy, effectiveness, or harms? … Prioritization and Selection of Harms for Inclusion in Systematic Reviews.

354. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 -  Are the decisional dilemmas centered on efficacy, effectiveness, or harms? … First, RCTs may be underpowered to detect differences between comparators in harms. … small and/or of too short duration for uncommon harms or longer-term harms to be detected. … o Are the decisional dilemmas centered on efficacy, effectiveness, or harms? … Prioritization and Selection of Harms for Inclusion in Systematic Reviews.

355. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - More research is needed to truly determine the balance of benefits to harms. … More research is needed to truly determine the balance of benefits to harms with mechanical thrombectomy … The balance of benefits to harms cannot be determined for these device classes. … More research is needed to truly determine the balance of benefits to harms. … The balance of benefits to harms cannot be determined for these device classes.

356. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
     June 01, 2013 - Key Question 3 addresses the comparative benefits and harms of local nonsurgical therapies in patients … What are the comparative benefits and harms of local nonsurgical definitive therapies for documented … What are the comparative benefits and harms of local nonsurgical definitive therapies for documented … What are the comparative short- and long-term benefits and harms of local nonsurgical therapies given … A prospective cohort study may be able to answer some questions about relative harms and benefits of

357. Wireless-Motility-Capsule Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
     May 01, 2013 - scintigraphy† Harms Low 2 Harms associated with WMC are minimal and no major safety issues were reported … ROM† Harms Low 5 Harms and adverse events were infrequently reported for WMC or ROM. … WMC is comparable to ROM with regard to harms. ROM involves exposure to at least one x ray. … Studies infrequently reported harms and adverse events for WMC or ROM. … We had only imprecise estimates of the effects on treatment decisions and harms.

358. Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
     December 01, 2017 - Based on the available literature, there is still uncertainty about the balance of benefits and harms … current. 2 This report’s main objective is to conduct a systematic review of the benefits and harms … In this review, we address the following Key Question (KQ): What are the benefits and harms of using

359. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - Although there are fewer transfusions, the balance of benefits and harms and whether there is a net … EPC)2 and another conducted by Cochrane Collaboration.40 Highlighting concerns over benefits and harms … Most fundamental is the balance of potential benefits (QoL, fewer transfusions) and harms (increased … Epoetin (alfa or beta) versus no ESA; What are the comparative benefits and harms of erythropoiesis … Benefits and harms of erythropoiesis- stimulating agents for anemia related to cancer: a meta-analysis

360. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
     September 27, 2012 - This report aims to compare the effectiveness and harms of liver-directed therapies for the indications … In addition to comparative effectiveness, the comparative harms of liver-directed therapies will be … Harms systematically reviewed by strict patient-selection criteria will summarize the available data … to evaluate the balance of benefits and harms of these therapies. … Harms under review include, but are not limited to, hepatic abscess, hemorrhage, injury to adjacent