-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - Two studies reported harms associated
with imaging for HCC. … One study reported harms. … No study reported
harms associated with imaging for HCC staging. … downstream harms related to false-positive tests or
subsequent workup, or potential harms related … No study on US with contrast reported harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - Harms (e.g., discrimination or victim
blaming)
Key Question 3. … For KQ 2 (treatment effectiveness and harms), we
grouped by outcome category. … Effectiveness and Harms
of Interventions
Evidence for the effectiveness and harms of TWH
interventions … None of these studies prespecified harms as an
outcome of interest. … Effectiveness and
Harms of Interventions
Evidence for the effectiveness and harms of TWH
interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - Question 5
Among adolescents and young adults with ASDs, what harms are associated with available … Harms are defined by the Evidence-based Practice Center Program as all possible adverse
consequences … of evidence related to
harms. … Harms are defined by the Evidence-based Practice Center Program as the totality of all possible … Question 4
Among adolescents and young adults with ASDs, what harms are associated with available
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
July 01, 2023 - What is the frequency and severity of harms associated with fatigue and sleepiness
of clinicians due … What patient safety practices (PSPs) have been used to prevent or mitigate the
harms associated with … What is the rationale for the PSPs used to prevent or mitigate the harms associated
with fatigue and … best answer the questions without conducting a systematic search for all
evidence on the targeted harms … We will
focus on the harms and patient safety measures or indicators that are addressed in the
studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - This report addressed benefits and harms
of nonopioid pharmacologic treatments in adults with chronic … How do harms vary depending on: (1) the specific type or
cause of pain, (2) patient demographics, (3 … : (2 new)
2b Harms in subgroups: no new
5
Harms:
• Two new trials reported harms of gabapentin … Harms and Adverse Events ...................................................................... … Harms and Adverse Events
a.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
September 30, 2010 - What are the harms from pharmacologic treatments when compared with no active
treatment?
4. … What are the harms from nonpharmacologic treatments when compared with each other?
6. … We will analyze harms regardless of how authors perceived causality of the
study treatments. … Harms:
1. Adverse events resulting from drugs.
2. … harms regardless of how authors perceived causality of treatments.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
September 01, 2011 - Clinical endpoints, which included
neonatal health outcomes and maternal/neonatal harms,
were assessed … Key Question 3: increase the maternal harms of
arrhythmia, heart failure, hyperglycemia,
hypokalemia, … (Key Question 4)
Neonatal harms data were very sparse. … Data on clinical outcomes,
neonatal/maternal harms, and pump-related outcomes were sparse. … The evidence was
inconclusive for all other neonatal health outcomes,
neonatal harms, maternal harms,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - There
is universal recognition of the harms associated with
postpartum depression and the potential … of positive results.
3
In addition, there is a paucity of evidence on the overall
balance of harms … Harms outcomes were framed to help identify
adverse events (e.g., stigmatization, decreased quality … To estimate the balance of benefits and harms of different
screening strategies, we also adapted an … Only the study conducted in Hong Kong
provided any evidence regarding harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - The results of the review and the evidence-based conclusions about effectiveness and harms of pain management … Comorbidities can affect both perception of pain and response to pain treatments (both benefits and harms … Harms that may extend beyond the acute-care setting are also unexamined. … There is limited evidence about the benefits and harms of pain-control interventions when they are used … There is limited evidence about the benefits and harms of pain-control interventions when they are used
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - The results of the review and the evidence-based conclusions about effectiveness and harms of pain management … Comorbidities can affect both perception of pain and response to pain treatments (both benefits and harms … Harms that may extend beyond the acute-care setting are also unexamined. … There is limited evidence about the benefits and harms of pain-control interventions when they are used … There is limited evidence about the benefits and harms of pain-control interventions when they are used
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - DMARD: No head-
to-head evidence met inclusion criteria; unable
to draw conclusions on the comparative harms … KQ 4: What are the comparative benefits and harms of drug therapies for PsA in subgroups of patients … MODERATE)
New Evidence:
KQ 3: For patients with PsA, do drug therapies differ in harms … No head-to-head studies met inclusion
criteria; unable to draw conclusions on the comparative
harms … DMARD: No head-to-head evidence
met inclusion criteria; unable to draw conclusions on the
comparative harms
-
effectivehealthcare.ahrq.gov/sites/default/files/linking-evidence-reviews-tools.pdf
May 29, 2025 - Key Quesetions
As You Listen to the Evidence
Overall Findings
Lifestyle Interventions
Results
Harms
-
effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
February 29, 2016 - Harms
b. Comparative Effectiveness
i. Comparative Harms
2. Nonpharm
a. Effectiveness
i. … Harms
b. Comparative Effectiveness
i. … Acetaminophen: no mention of harms. … Opioids: insufficient mention of harms
related to long-term risks. … The long-
term harms of opioids are extremely
serious.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - What are the harms from nonpharmacological treatments when compared with each
other?
6. … What are the harms from nonpharmacological treatments when compared with each other?
6. … Weight Loss
Weight loss and exercise improved UI in
obese women without evident harms. … What are the harms from nonpharmacological treatments when compared with each other?
6. … What are the harms from nonpharmacological treatments when compared with each other?
6.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - The original proposed Key Questions addressed the benefits and harms of various
fractionation schedules … revised to
cover a broader range of target volumes and included the investigation of benefits and harms … receiving moderate or ultra-
hypofractionated EBRT with curative intent, what are the benefits and harms … receiving moderate or ultra-
hypofractionated EBRT with curative intent, what are the benefits and harms … receiving moderate or ultra-
hypofractionated EBRT with curative intent, what are the benefits and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
October 01, 2021 - comparable patient
satisfaction with breasts (Low SoE); however, TRAM flaps probably
increase the risk of harms … Our conclusions about comparative
effectiveness and harms are based solely on the comparative studies … satisfaction with breasts (Low SoE) and risk
of necrosis (Low SoE), but TRAM probably poses greater risk of harms … ~ ~
Harms to area of flap harvest . . . . . ◆◆ Increased abdominal bulge/hernia,
hernia repair surgery
-
effectivehealthcare.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
July 23, 2012 - • How often do harms occur?
• How strong is the
evidence?
• Is the condition
exaggerated? … the stories
fail to:
o Discuss
costs
o Quantify
potential
benefits
o Quantify potential harms … Communication of Evidence
• Exaggerate or emphasize benefits of interventions
• Ignore or minimize potential harms … context into
account,
including
the patient's values regarding
specific
benefits and
harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - laboratory diagnostic tests, the effectiveness of prevention
strategies, and the effectiveness and harms … What are the harms associated with prevention strategies? … KQ3: What is the comparative effectiveness and harms of different antibiotic treatments?
a. … KQ4: What are the effectiveness and harms of nonantibiotic adjunctive interventions?
a. … There are various ways to
assess harms; each has problems.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - These
may also have serious harms including dependence, addiction, and physiological
withdrawal potential … chronic pain.7,15 The purpose of this systematic review was to evaluate the evidence on
benefits and harms … benefit or harm, but were not so wide that they
included the potential for both meaningful benefits and harms … Key Question 2: Harms of cannabinoids for chronic pain compared with placebo in the
short term (4 weeks … The comparisons of effects on serious and long-
term harms are however not possible, even indirectly.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - The 2020
report addressed benefits and harms of opioid, nonopioid pharmacologic, and nonpharmacologic … pain conditions, the report addressed the effectiveness and
comparative effectiveness (benefits and harms … harms, infections,
cardiovascular events, cognitive harms, and psychological harms (e.g., depression … harms, cardiovascular-
B-3
related harms, kidney-related harms, falls, fractures, motor vehicle … accidents,
endocrinological harms, infections, cognitive harms, and psychological harms (e.g.,
depression