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effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - Key Question 2
What are the harms, including adverse events, associated
with medical, behavioral, and … For KQ2, we did not rate of strength
of evidence because a fully inclusive assessment of harms
could … Using
predefined criteria, we found 25 publications about harms
that were eligible for inclusion. … This makes detection
of harms challenging. … Across agents data are
sparse to evaluate long-term improvements and risk
of harms.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - There was evidence regarding the benefits or harms of
screening with diabetes for macroalbuminuria … No direct data currently exist regarding benefits and harms of
screening for or monitoring of CKD in … of non-diabetic adults for CKD improves clinical
outcomes or increases harms. … the same as evidence that there are no
harms associated with monitoring.
11. … be explicit about
what types of harms these studies should be paying attention
to.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. … It also allows one to evaluate the tradeoff in benefits, harms, and costs of different test-and treat … of treatment in true-positive diagnoses and avoidance of harms of treatment in true-negative diagnoses … Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. … Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. … It also allows one to evaluate the tradeoff in benefits, harms, and costs of different test-and treat … of treatment in true-positive diagnoses and avoidance of harms of treatment in true-negative diagnoses … Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. … Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
June 21, 2021 - Harms (KQ1f and 2f) will also be
addressed. … f) What are the harms of telehealth for women’s reproductive health? … f) What are the harms of telehealth for screening and interventions for interpersonal
violence? … :
o Health care avoidance
o Psychological harms (e.g., anxiety, shame, guilt, stigma)
IPV • Health … o Increased abuse or other forms of retaliation; and other reported harms of screening
or identif
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - January 2012
Surveillance Report:
October 2012
Key Findings:
- The conclusions for KQ2 (harms … of screening) and KQ4
(harms of monitoring), KQ6 (harms of treatment) are still
considered valid … considered valid but additional studies are available
- For KQ5 (benefits of treatment) and KQ6 (harms … CKD Screening Benefits and Harms
12
Conclusions From CER
Executive Summary
RAND Literature … screening of
adults for CKD improves clinical outcomes
or increases harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - Objectives
The objectives of the current review are to examine the benefits and harms of concomitant … In response to the third specific comment, harms will not be measured but
rather extracted as measured … Do the effect estimates of harms outcomes vary by age, ethnicity, gender, or health status?
b. … (McHarm)31 for primary
studies evaluating harms of treatment. … (from the
McHarm checklist31): prespecified and valid
definition of harms, mode of harms
collection
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
March 25, 2012 - What are the significant agent-specific harms/adverse effects of
nonhormone therapies? … A point was raised about combining
benefits and harms into a KQ. … RCTs = randomized controlled trials
Key Question 2—Other Benefits/Harms Hormones
We will use a … RCTs = randomized controlled trials
Key Question 3—Nonhormone Other Benefits/Harms
We will limit … What is the best evidence for determining harms of medical treatment?
CMAJ 2006;174(5):645-6.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
October 01, 2011 - This is
because the focus of the review is on comparative benefits and
harms. … Absolute rates are provided throughout the harms
section when available (see GI and CV harms of celecoxib … , GI
and CV harms of nonselective NSAIDs, GI and CV harms of
aspirin). … Earlier section explains that RA trials included for
assessment of harms only. … Reviewing general harms associated with PPIs was outside the
scope of this review; we reported harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - Evidence
of both benefits and harms of adding a supplement to
cardiovascular drugs has been reported … Clinical or intermediate harms outcomes
(e.g., organ toxicity, serious adverse events, withdrawal
due … Do the effect estimates of harms outcomes vary by age,
ethnicity, gender, or health status?
b. … Benefits and harms are measured as outcomes that
may be clinical outcomes, their proxy surrogates, or … • Reported clinical or surrogate cardiovascular efficacy
or harms, or pharmacokinetic outcomes, in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - pain, effectiveness of interventions to mitigate risks of overdose
or suicide, or how benefits and harms … • No systematic review evaluated benefits and harms of interventions to mitigate risks of
harms ( … • No systematic review evaluated how benefits and harms of tapering support interventions
varied … Incorporates issues around both clinical
benefits and potential clinical harms
Yes
2d. … Evidence on strategies to mitigate
serious harms of tapering (overdose,
suicide) is lacking.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
April 01, 2021 - pain, effectiveness of interventions to mitigate risks of overdose
or suicide, or how benefits and harms … • No systematic review evaluated benefits and harms of interventions to mitigate risks of
harms ( … • No systematic review evaluated how benefits and harms of tapering support interventions
varied … Incorporates issues around both clinical
benefits and potential clinical harms
Yes
2d. … Evidence on strategies to mitigate
serious harms of tapering (overdose,
suicide) is lacking.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - What are the harms from preventive pharmacologic
treatments when compared with placebo or no active … What are the harms from preventive pharmacologic
treatments when compared with active pharmacologic … Risk of Bias Assessment
We evaluated the risk of bias in individual studies for
benefits and harms … KQ 2: What are the comparative harms from pharmacologic treatments for preventing migraine attacks in … We did not contact the authors
requesting unreported benefits and harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - We assessed
treatment-related harms and adherence. … What are the harms from RLS
treatments?
a. … What are the harms from RLS
treatments?
a. … What are the long-term harms from
treatment? … Short-Term Harms
We evaluated three measures of short-term treatment
harms from randomized placebo controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
July 01, 2013 - What are the harms to older adults as a result of HCBS and NHs? … while NH residents
experienced higher rates of other harms. … What are the harms to older adults as a result of HCBS and NHs? … while NH residents
experienced higher rates of other harms. … What are the harms to older adults as a result of HCBS and NHs?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - What are the benefits and harms of psychosocial and other non-pharmacological
treatments for adults … How do the benefits and harms of nonpharmacological treatments for adults with
schizophrenia vary by … of antipsychotic drugs,
populations can be mixed-diagnoses, as the harms are not
population-specific … of any included intervention, systematic reviews of
observational studies to evaluate harms will be … o For studies specifically on harms of antipsychotic drugs, populations can be mixed-diagnoses, as the
-
effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
August 13, 2018 - Do the effectiveness/harms vary by patient characteristics or presentation of illness? … Do the benefits and harms vary by patient characteristics or presentation of illness? … Do the benefits and harms vary by patient characteristics or presentation/course of
illness? … Do the benefits and harms vary by patient characteristics or presentation/course of
illness? … addresses both benefits
and potential harms.
2e.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - This review summarizes the evidence on the
comparative long-term benefits and harms of ACEIs,
ARBs, and … strength of
evidence and brief conclusions from this review of the
comparative long-term benefits and harms … Summary of evidence on comparative long-term benefits and harms of ACEIs,
ARBs, and direct renin inhibitors … Summary of evidence on comparative long-term benefits and harms of ACEIs,
ARBs, and direct renin inhibitors … (4) The potential to gain insight on the comparative
benefits and harms of ACEIs, ARBs, and direct
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - Key Question 3: What are the harms of interventions
intended to achieve or maintain smoking cessation … Data on harms or
adverse effects of included interventions are captured in
Key Question 3. … Intervention Harms for Pregnant
and Postpartum Women
We identified four studies that reported harms … None of the studies that
evaluated relapse prevention interventions reported harms
data. … Harms data were
rarely reported.
References
1. Centers for Disease Control and Prevention.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-evidence-summary_0.pdf
June 01, 2021 - Summary
Main Points
• Four Key Questions addressed the comparative benefits and harms … endotracheal intubation [ETI]); Key
Question 3 – SGA versus ETI; and Key Question 4 – how the benefits and harms … arrest
c Success was qualitatively synthesized for KQ1 and 2; results available in full report
d Harms … were qualitatively synthesized; meta-analysis not possible as harms are different
Also included in