-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_disposition-comments.pdf
February 11, 2013 - Greater attention to assessment of risk of harms and harms/benefits is merited
and may suggest the need … We have included KQ4 as our
assessment of harms in the included
studies. … We did not find many studies to
report harms. … We do make an effort to
weigh these harms with the potential
benefits. … .”The
distinction between no evidence of harms
and evidence of lack of harms is made in
the Methods
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - We view effectiveness
in terms of both benefits and harms, so we frame our
questions to address each … KQ 3
addresses specific patient, intervention, or setting factors
that may modify benefits or harms … KQ 2: Regarding harms for adult psychiatric patients in
acute care settings:
a. … For those with active aggression, what are the
comparative harms of strategies, including seclusion … of prevention), one CRT; and KQ 2b (harms
of de-escalating aggression), four RCTs and two NRCTs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
May 04, 2013 - We were able to observe harms
within this literature base. … Suggested change: The issue of harms/adverse events of tubes vs. … We have examined short v. long term tubes in
terms of benefit and harms. … Because many of the studies were
small, harms data is sparse. … We have revised the results concerning harms
from adenoidectomy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - in Adult Patients With Exacerbation of COPD
Purpose of Review
To evaluate the effectiveness and harms … , the benefits
and harms of treatments for ECOPD that have
been found efficacious in stable COPD , … the
benefits and harms of antibiotics and systemic
corticosteroids in mild ECOPD, the benefits
and … In adult patients with exacerbation
of COPD, what are the benefits and harms
of emerging and other … In adult patients with exacerbation of COPD,
what are the benefits and harms of emerging and
other
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-epilepsy-amended-protocol.pdf
March 07, 2021 - What are the harms or comparative harms of treatments for infantile epilepsy? … Timing Effectiveness: 12 week minimum follow-up
Harms: No minimum follow-up
Setting Setting not … What are the harms or comparative harms of not treating infantile epilepsy? … For Key Question 3 (harms), we will include single-arm studies as well as controlled
studies.
6. … However, for harms data, we will extract data from all
reported time points.
-
effectivehealthcare.ahrq.gov/sites/default/files/searching.ppt
January 01, 2011 - Efficacy and harms searches may be separate. … intervention and harms and/or disease. … In a harms search, including just the intervention and harms may be permissible. … Harms Searching
To make informed health care decisions, the balance of benefits to harms needs to be … This can be important for determining efficacy and harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - This review should help 1) better
understand long-term benefits and harms associated with different … Outcome
measures for harms, or adverse events, are the same as in KQ3, and KQ5 below. … First, by using data from clinical trials and large cohort studies, evidence of
benefits and harms of … Documented short- and long-term benefits and harms of surgical procedures will
be compared too; the … Benefits and harms for specific subpopulations (by gender, age, and
race/ethnicity) and other patient
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - been
a near disappearance of the use of FGAs
Purpose of Review:
To assess the effectiveness and
harms … Harms
(KQ2) were reported in 126 studies (93%). … Several studies found no significant differences
in harms for different age groups. … Treatment benefit and harms were examined most
frequently for schizophrenia. … One of the greatest priorities for future research is the
systematic evaluation of harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
July 01, 2012 - Key Question 2
What harms result from public reporting? … Harms are another potential
consequence of public reporting (Key Question 2). … Key Question 2: What harms result from
public reporting? … Studies that examined harms found more evidence of
no harm than evidence of harm. … harms is
limited and most studies do not confirm the potential
harm.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-information-exchange_research-protocol.pdf
April 20, 2015 - What harms have resulted from HIE? … Do harms vary by type of HIE?
2b. Do harms vary by health care settings and systems?
2c. … Do harms vary by the IT system characteristics?
3. … What specific usability factors impact the effectiveness or harms from HIE?
5c. … KQ 2
Harms
KQ 2
Intermediate
outcomes
Harms
KQ 2
Source: www.effectivehealthcare.ahrq.gov
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - ; and examine how benefits and harms vary by
age, breast cancer risk status, and other factors. … What is the evidence for harms of
tamoxifen citrate, raloxifene, and tibolone when used
to reduce risk … What is the evidence that harms or
secondary potential benefits listed above affect
treatment choice, … Harms of tamoxifen citrate,
raloxifene, and tibolone when used for primary
prevention of breast cancer … :
• In addition to the 8 large randomized controlled
trials described in Key Question 1, harms data
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - How do these harms vary by dose or
formulation, duration of use, or specific population? … KQ 6: Based on the comprehensive literature review, what are the benefits and harms from the
use of … While on OCs, women are at risk for both short- and long-term harms,
some of which may be fatal. … How do
these harms vary by
dose or formulation,
duration of use, or
specific population? … How do these harms
vary by dose or
formulation, duration
of use, or specific
population?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - Key Question 2: What are the harms, including adverse events, associated with medical,
behavioral, … 2
(e.g., thromboembolic events, emotional side effects, weight gain,
short- and long-term harms) … conception
Additional
interventions
Interventions
Medical
Behavioral
CAM
Harms … conducting a systematic
review of harms data.
43
As a meta-analysis is not likely to be feasible … Challenges in systematic reviews that assess treatment harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - Reviews are systematic reviews of existing research on the effectiveness,
comparative effectiveness, and harms … on the efficacy or effectiveness of a single intervention, by comparing the relative benefits and
harms … The
inception date also allows investigators to capture the benefits and harms that occurred after a … A potential advantage of this type of study is that long-
term benefits, tolerability, and harms can … AHRQ
series paper 4: assessing harms when comparing
medical interventions: AHRQ and the Effective
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - Reviews are systematic reviews of existing research on the effectiveness,
comparative effectiveness, and harms … on the efficacy or effectiveness of a single intervention, by comparing the relative benefits and
harms … The
inception date also allows investigators to capture the benefits and harms that occurred after a … A potential advantage of this type of study is that long-
term benefits, tolerability, and harms can … AHRQ
series paper 4: assessing harms when comparing
medical interventions: AHRQ and the Effective
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - Harms 12 Low
A small, but notable, proportion of patients experience harms due to renal mass biopsy, … Studies were inconsistent in which
harms, if any, were reported.
Table C. … Harms 16 Low
A small, but notable, proportion of patients experience harms due to renal mass biopsy, … Studies were inconsistent in which
harms, if any, were reported. … Harms were evaluated as urologic and nonurologic
complications.
-
effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/1002-nonpharmacologic-treatment-topic-brief.pdf
June 03, 2024 - Issue: The nominator of this topic is interested the benefits and harms of nonpharmacologic
treatments … What is the effectiveness and comparative effectiveness and harms of non-pharmacologic
treatments for … mental health conditions
prompts questions about the benefits and harms of nonpharmacologic treatment … Incorporates issues around both clinical
benefits and potential clinical harms
Yes
2d. … , fetal/neonatal/child harms
2.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - What are the adverse effects or harms associated with imaging-based surveillance
strategies? … What are the adverse effects or harms associated with using imaging techniques related to
testing or … o Key Questions 1d, 2d, and 3d (Adverse Events or Harms)
Adverse effects or harms associated with … Adverse effects or harms associated with test-associated diagnostic workup (e.g.,
harms of biopsy … or harms associated with workup of other incidental tumors
discovered on imaging)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
June 21, 2019 - The objective is to
understand the benefits and harms of physical activity for people currently using … Does physical activity reduce the harms of immobility, such as incidence of
decubitus ulcer, urinary … What are the harms of physical activity, such as injuries that are associated with
wheeled mobility … Do the benefits or harms of physical activity vary by the location of the
intervention (e.g., home, … Do the benefits and harms of physical activity vary by age, sex, or race/ethnicity?
b.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
May 01, 2010 - • Are there patient subpopulations where harms are
more likely? … Regarding the benefits and harms of
rFVIIa, our findings include:
Figure C. … • Current evidence of low strength is too limited to
compare harms and benefits. … • Current evidence is insufficient for comparing
harms and benefits. … • Current evidence is insufficient for comparing
harms and benefits.