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Showing results for "harms".

181. Enzyme-Replacement Therapies for Lysosomal Storage Diseases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lysosomal-storage-diseases-therapies/technical-brief
     January 02, 2013 - The purpose of a Technical Brief is to report what outcomes (benefits and harms) have been studied for … comparative effectiveness review or systematic review that draws conclusions as to the clinical benefits and harms … Harms reported to the FDA and in clinical studies were primarily allergic, including infusion-associated

182. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/traumatic-brain-injury-rehabilitation/research
     June 20, 2012 - evaluate evidence on participation outcomes of productivity and community integration and treatment harms … One study addressed harms and found no treatment-related harms.

183. Dietary Supplements in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/dietary-supplements/research
     April 30, 2012 - Objectives For supplements commonly used by patients with cardiovascular disease, we examined benefits, harms … Evidence was insufficient for all gradable clinical efficacy and harms outcomes (e.g., mortality, thrombotic … Evidence regarding harms was inconclusive.

184. Cancer-Ovarian-Contraceptives Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
     June 01, 2013 - Also, because the majority of evidence on noncontraceptive benefits and harms of OC use is derived from … 3 KQ 5: What are the harms of OC use, including breast cancer incidence, cervical cancer incidence … How do these harms vary by dose or formulation, duration of use, or specific population? … KQ 6: Based on the comprehensive literature review, what are the benefits and harms from the use of … For incident harms and benefits, the likelihood that benefits outweighed harms was less than 40 percent

185. Systematic Review Update: Noninvasive Nonpharmacologic Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
     December 11, 2018 - What are the benefits and harms of noninvasive nonpharmacologic therapies compared with exercise? … What are the benefits and harms of noninvasive nonpharmacologic therapies compared with exercise? … What are the benefits and harms of noninvasive nonpharmacologic therapies compared with exercise? … What are the benefits and harms of noninvasive nonpharmacologic therapies compared with exercise? … What are the benefits and harms of noninvasive nonpharmacologic therapies compared with biofeedback?

186. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - Assessing the Risk of Bias for Harms Although the assessment of harms is almost always included as an … Although reviewers recognize the importance of harms outcomes, harms are generally ignored in risk-of-bias … The McMaster University Harms scale (McHarm) was developed specifically for evaluating harms and is … Was the mode of harms collection specified as ACTIVE? 6. … Did the study specify WHO collected the harms? 8.

187. Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in Women | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-cancer-medications/research
     September 14, 2009 - raloxifene, and tibolone to reduce risk for primary breast cancer, assess the nature and magnitude of harms … , and examine how benefits and harms vary by age, breast cancer risk status, and other factors.

188. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - This systematic review assesses the comparative effectiveness and harms of PBI compared with WBI for … cm that has minimal or no lymph node involvement (N0/1), and how differences in effectiveness and harms … Comparative Effectiveness and Harms of PBI Versus WBI Thirteen RCTs reported in 38 articles with a … total of 15,276 patients were included in the assessment of the comparative effectiveness and harms … of PBI Versus WBI Comparative Effectiveness and Harms of PBI Modalities Financial Toxicity Related

189. Nonsurgical Treatments for Urinary Incontinence in Adult Women: (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
     June 06, 2017 - What are the harms from nonpharmacological treatments when compared with no active treatment? … What are the comparative harms from nonpharmacological treatments when compared with each other? … What are the harms from pharmacological treatments when compared with no active treatment? 2c. … What are the comparative harms from pharmacological treatments when compared with each other? … KQ 4: What are the benefits and harms of combined nonpharmacological and pharmacological treatment

190. Moyer_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
     January 01, 2012 - studies, but reviews and  assesses existing   research o Evaluates the balance of benefits and harms … when the evidence is insufficient in quality or quantity Slide 4: Balance  of Benefits  and Harms … Benefits – Harms = Net Benefit Source: Eisenberg Center Conference Series 2012: Supporting  Informed … There is moderate or hig certainty  that the  service has no net benefit or that the harms outweigh … USPSTF concludes  that current evidence is insufficient to  assess the balance of benefits and harms

191. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-and-harms-of-treatments-for-traumatic-brain-injury-preliminary-key-questions-1-what-is-the-comparative-effectiveness-of-the-treatments-for-tbi-for-grades-i-iv-2-for-patients-what-are-the-
     December 07, 2009 - What is the comparative effectiveness and harms of treatments for traumatic brain injury? … For patients, what are the potential harms of TBI treatment interventions? … quality of life, hospitalizations/ER visits Describe any health-related risks, side effects, or harms … Evidence regarding effectiveness and harms of treatments, or information regarding the lack of evidence

192. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - How are patient factors related to the harms of different imaging techniques? b. … For KQ3 on the rates of procedural harms, we included any reported harms data based on 50 or more patients … – For harms (KQ3), this means a statement appearing in the Methods section that harms/complications … We did not grade the strength of evidence for harms. … , the harms of concern are different for different tests.

193. Long-Term Care for Older Adults: A Review of Home and Community-Based Services Versus Institutional Care | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/long-term-care-adults/research
     November 07, 2012 - trajectories for physical function, cognition, mental health, mortality, use of acute care services, harms … HCBS with NHs, low-strength evidence suggested that HCBS recipients experienced higher rates of some harms … while NH residents experienced higher rates of other harms.

194. Screening for Methicillin-Resistant Staphylococcus Aureus (MRSA) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mrsa-screening-2010/research
     June 20, 2013 - Structured Abstract Objectives To synthesize comparative studies that examined the benefits and harms … insufficient evidence on other outcomes of universal MRSA screening, including morbidity, mortality, harms … screening and infection control interventions and address outcomes, including morbidity, mortality, harms

195. Child and Adolescent Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Trauma Other Than Maltreatment or Family Violence | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/trauma-child-interventions/research
     February 11, 2013 - subgroup characteristics that moderate the effect of an intervention on outcomes (KQ 3); and to assess harms … We also found almost no evidence on harms associated with psychological treatments. … Only pharmacological interventions attempted to assess harms in this vulnerable population.

196. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - This trial had low risk of bias, and harms were well monitored and reported. … How do the harms compare across different interventions? … Harms for interventions for both adults and adolescents were predominately derived from RCTs. … This trial had low risk of bias, and harms were well monitored and reported. … How do the harms compare across different interventions?

197. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - must be balanced against the potential harms to mother and fetus of untreated depression. … Objectives The objective of this systematic review was to evaluate the benefits and harms of various … What are the comparative harms of pharmacological and nonpharmacological treatments for women with … Child Harms Evidence on harms to the child of a mother treated for depression during pregnancy was limited … These studies contributed to the evidence on potential harms with treatment during pregnancy.

198. Management of Primary Headache During Pregnancy | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/headaches-pregnancy/protocol
     November 12, 2019 - Specifically, the review will address: (1) the (comparative) benefits and harms of pharmacologic and … For harms, we will also search the U.S. … For harms, we will also search the U.S. … We expect to summarize harms data semi-quantitatively (i.e., without meta-analysis). … We expect to primarily rely on reported within-study differences in effects (or harms).

199. Management of Primary Headache During Pregnancy: Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
     March 23, 2019 - Specifically, the review will address: (1) the (comparative) benefits and harms of pharmacologic and … o For harms, we will also search the U.S. … o For harms, we will also search the U.S. … We expect to summarize harms data semi-quantitatively (i.e., without meta-analysis). … We expect to primarily rely on reported within-study differences in effects (or harms).

200. Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
     December 18, 2019 - 1a: How do effectiveness and harms vary by choice of prostaglandin? … • Include high quality cohort and case-control studies for harms. … • Include high quality cohort and case- control studies for harms. … • Include high quality cohort and case- control studies for harms. … • Include high quality cohort and case-control studies for harms.