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effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-key-ques.pdf
January 01, 2023 - What are the benefits and harms of interventions to treat conditions occurring at increased or decreased … What are the benefits,
harms of screening approaches
for conditions occurring at
increased prevalence … adults (non-pregnant)
• Benefits: accurate diagnosis, time to
diagnosis or intervention
• Harms … diagnosis
• Benefits: Time to intervention/treatment
• Health and quality of life outcomes
• Harms … What are the benefits
and harms of interventions to
treat conditions occurring at
increased prevalence
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effectivehealthcare.ahrq.gov/products/appendicitis/research
December 14, 2015 - cohort studies that reported information on test accuracy for the diagnosis of acute appendicitis or harms … Only a few studies reported information on harms, leading to concerns about selective outcome reporting … Therefore, no definitive conclusions could be drawn about patient-relevant outcomes or harms. … limited to allow the identification of modifiers of test performance, patient-centered outcomes, or harms … modifiers; and to evaluate the impact of testing strategies on patient-relevant outcomes, resource use, and harms
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effectivehealthcare.ahrq.gov/products/allergy-seasonal/research
July 16, 2013 - population, we did not find evidence that any single treatment was both more effective and had lower risk of harms … Evidence for both effectiveness and harms was insufficient regarding the comparison between oral selective … All effectiveness and harms outcomes were limited by short trial durations. … For most harms comparisons, the evidence was insufficient.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/bimp-key-questions.pdf
January 01, 2022 - What are the benefits and harms of behavioral interventions, either alone or in
combination with other … What are the benefits and harms of behavioral interventions delivered via telehealth and
digital health … What is the comparative effectiveness and harms of a behavioral intervention for migraine
prevention … What is the comparative effectiveness and harms of behavioral interventions delivered via
telehealth … What are the benefits and harms of non-headache focused behavioral interventions (e.g.,
CBT for insomnia
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effectivehealthcare.ahrq.gov/products/labor-nitrous-oxide/research
August 23, 2012 - Most maternal harms reported in the literature were unpleasant side effects that affect tolerability … Evidence about occupational harms and exposure was limited. … needed across all of the Key Questions addressed: effectiveness, women's satisfaction, route of birth, harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - What are the adverse effects or harms associated with
using imaging techniques, including harms of test … What are the adverse effects or harms associated with
using imaging techniques, including harms of test … – Harms of testing per se (e.g., radiation exposure)
– Harms from test-directed treatments
(e.g … Harms. … What are the adverse effects or
harms associated with using imaging techniques,
including harms of
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effectivehealthcare.ahrq.gov/products/breast-reconstruction-mastectomy/protocol
June 18, 2020 - undergoing (or have undergone) mastectomy for breast cancer, what are the comparative benefits and harms … adult women undergoing AR after mastectomy for breast cancer, what are the comparative benefits and harms … We expect to summarize harms data semiquantitatively (i.e., without meta-analysis). … We expect to primarily rely on reported within-study differences in effects (or harms). … For KQ 6 (flap types for AR) we will also include in the SoE tables harms to area of flap harvest.
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effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment/protocol
November 03, 2020 - Similarly, it is important to identify harms and adverse effects of PBCs. … 21 , 22 Hence, the initial best use of the current evidence may be to clearly delineate potential harms … In adults with chronic pain, what are the harms of cannabinoids? … In adults with chronic pain, what are the harms of kratom or other plant-based substances for treatment … We do not anticipate excluding observational studies assessing harms.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - Harms and Adverse Events
a. … harms, infections, cardiovascular
3
events, cognitive harms, and psychological harms (e.g.,
depression … endocrinological harms, infections,
cardiovascular events, cognitive harms, and psychological
harms … Harms and adverse events
a. … harms, infections, cardiovascular
events, cognitive harms, and psychological harms
(e.g., depression
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effectivehealthcare.ahrq.gov/system/files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - o Interventional radiology: The evidence is insufficient regarding the benefits or
harms of percutaneous … There remain uncertainties about
the effectiveness and harms of various treatment options, preventive … This systematic review evaluates: (1) the accuracy of CT and harms related to false
positive, false … negative, and incidental findings on CT imaging; (2) the effectiveness and
harms of hospitalization … the
need for colonoscopy in people with a history of diverticulitis; and (4) the effectiveness
and harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - o Interventional radiology: The evidence is insufficient regarding the benefits or
harms of percutaneous … There remain uncertainties about
the effectiveness and harms of various treatment options, preventive … This systematic review evaluates: (1) the accuracy of CT and harms related to false
positive, false … negative, and incidental findings on CT imaging; (2) the effectiveness and
harms of hospitalization … the
need for colonoscopy in people with a history of diverticulitis; and (4) the effectiveness
and harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
August 08, 2019 - harms, infections, cardiovascular events,
cognitive harms, and psychological harms (e.g., depression … How do harms vary depending on: (1) patient demographics (e.g., age, gender); (2) patient
medical or … harms, cardiovascular-related
4
harms, kidney-related harms, falls, fractures, motor vehicle … accidents, endocrinological
harms, infections, cognitive harms, and psychological harms (e.g., depression … MEDLINE Search Strategies
Treatment effectiveness and harms
1. Pain/
2. Acute Pain/
3.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - The objective of the current review is to address the comparative effectiveness and harms … Do benefits and harms differ between partial tonsillectomy and total tonsillectomy?
… Do benefits and harms differ by surgical technique (e.g., cautery, coblation)?
… Tables 2 and 3 indicate the outcomes and harms of interest. … McMaster Quality
Assessment Scale of Harms (McHarm) for primary studies.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/genitourinary-syndrome-key-questions.pdf
January 01, 2021 - therapeutic approaches is controversial and an independent review of the
evidence on benefits and harms … Consequently, a review that synthesizes the totality of evidence available on the benefits and
harms … What is the effectiveness and harms of screening strategies to identify GSM in peri- or
postmenopausal … What are the harms (and comparative harms) of hormonal, non-hormonal, and energy-based
interventions … What is the effectiveness and harms of endometrial surveillance among women who have a
uterus and are
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-bereaved-persons-key-questions.pdf
January 01, 2022 - What is the effectiveness and harms of universal screening people for bereavement and
response to loss … What are the effectiveness, comparative effectiveness, and harms of selective interventions
for at risk … What are the effectiveness, comparative effectiveness and harms of indicated interventions
for people … • Identification of
bereavement
• Referral to care
• Decreased
symptoms
• Patient
satisfaction
Harms … physical,
behavioral and
mental health
• Improved QoL
• Improved
functioning
• Patient
satisfaction
Harms
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effectivehealthcare.ahrq.gov/sites/default/files/prehospital-airway-management-draft-appendix-f.xlsx
June 22, 2020 - Trauma 99.6% vs. 99.3%, p=0.679 NR NA 224 1 566 4 Y, 7/29
Delorenzo, 2018 Harms ETI RSI RSI NR 743 … NA NA NA NA NA Harms Hypoxia As treated, airway attempted NA NA 1.3% (10/743) NR NA 10 733 NA NA NA … Delorenzo, 2018 Harms ETI RSI RSI NR 773 NA NA NA NA NA Harms Hypotension during RSI As treated, airway … Gausche, 2000
Gausche-Hill, 2000 Harms ETI NR NR NR 186 NA NA NA NA NA Harms Main stem intubation ETI … only NA NA 5% (10/203) NR NA 10 193 NA NA NA
Rumball, 2004 Harms ETI NR NR NR 203 NA NA NA NA NA Harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
January 01, 2007 - fibrosis, including
the potential benefits (growth outcomes, decreased hospitalizations, etc.) and harms … What is the evidence for harms of rhGH in CF patients? … The harms of rhGH will be an important aspect of the review conducted within the EHC Program.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - How are patient factors related to the harms of different imaging techniques?
b. … • We changed KQ 3 (harms) to “rates of harms” rather than simply “harms” to clarify the
focus on … how common the harms are, not simply what the possible harms are … Key Question 3 on the rates of procedural harms. … For harms (KQ 3), there is a statement in the Methods section that harms/complications
would be measured
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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - Insufficient Evidence of Maternal Harms. … Insufficient Evidence of Maternal Harms: Detailed
Synthesis. … Insufficient Evidence of Fetal, Infant, or Child
Harms. … or child
harms together. … Evidence of Fetal, Infant, or Child Harms:
Overview.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
April 09, 2020 - Specifically, the review will address the
(comparative) benefits and harms of:
• IBR versus AR (Key … We expect to summarize harms data
semiquantitatively (i.e., without meta-analysis). … We expect to primarily rely on reported within-study differences in effects (or harms). … of IBR and AR
• Relative clinical effects of IBR or IR before versus after chemotherapy
• Harms of … For KQ 6 (flap types for AR) we will also include in the
SoE tables harms to area of flap harvest.