-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - In addition, accumulating
evidence indicates increasing rates of harms associated with prescription … recent data
have reported potential associations between use of long-term opioid therapy and other
harms … Harms and adverse events
a. … harms, infections, cardiovascular events, cognitive harms,
and psychological harms (e.g., depression … ,
cardiovascular events, cognitive harms, and psychological harms (e.g.,
depression)
Exclude:
•
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
October 01, 2011 - What are the harms of screening? … What are the harms of treatment of
subclinical hypothyroidism and subclinical
hyperthyroidism? … What are the harms of screening? … Information about the harms of screening remains
sparse. … What are the harms of treatment of
subclinical hypothyroidism and subclinical
hyperthyroidism?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-protocol.pdf
January 01, 2024 - Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients during Clinical … Center Rapid Review Protocol
Project Title: Making Healthcare Safer IV: Programs for Responding to
Harms … Patients during Clinical Care
Review Questions
How effective are programs for responding to harms … How do such programs prevent or mitigate harms?
2. … , characteristics of the programs for responding to
harms, rationale for the programs, outcomes, unintended
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - We used
database and registry studies and case series for harms data
only. … Most studies reported harms data (see
Harms of Tonsillectomy section below). … Harms of Tonsillectomy
To account fully for potential harms of tonsillectomy,
primarily PTH and readmission … Unadjusted frequency of harms reported in
comparative studies. … McMaster Quality
Assessment Scale of Harms (McHarm) for primary studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
April 01, 2019 - Do telehealth consultations result in harms,
adverse events, or negative unintended
consequences? … • Adverse effects: Only studies of surgery
explicitly examined harms, but the study
limitations … • Adverse events: No information was available
about harms (insufficient evidence). … • Harms: Only two of studies explicitly examined
harms, reporting lower rates of complications
with … Low
Harms (KQ3) 2 Rates of complications and serious adverse events
reported in two studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
April 01, 2025 - dilemmas for this review include determining the most effective treatments (while
weighing benefits and harms … child/adolescent, clinical, or treatment characteristic or treatment history impacts the
benefits and harms … What are the harms associated with treating
children under 18 years of age for disruptive behaviors … Adverse effects/harms
--
Timing KQs 1-6. Any length of followup --
Setting KQs 1-6. … Evidence was inconsistent or insufficient to determine differential treatment benefits
and harms based
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - Comments_Comparative Effectiveness Review No. 265_Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms … Disposition of Comments Report
Title: Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms … Radiation Therapy for Metastatic Bone
Disease: Effectiveness and Harms. … What is the
effectiveness and what are the
harms of EBRT in the palliative
treatment of bone metastases
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
March 22, 2021 - or potential
effect modifiers of harms. … This
question was separate, and focused on
identifying evidence on outcomes (benefit and
harms) of … The
conclusions about fetal/neonatal harms are
relevant to the evidence on outpatient versus
inpatient … The question here
was about outcomes (benefits and harms) of
fetal surveillance when a prostaglandin … Like
harms and risks, these factors can impact
patients' decision-making regarding inpatient
versus
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
July 01, 2023 - What is the frequency and severity of harms associated with opioid prescribing and ordering?
2. … What patient safety measures or indicators have been used to examine the harms associated
with opioids … What opioid stewardship patient safety practices (PSPs) have been used to prevent or mitigate
the harms … the rationale for the opioid stewardship practices that have been used to prevent or
mitigate the harms … best answer the questions without conducting a systematic search for all
evidence on the targeted harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
March 11, 2010 - What are the harms of screening?
3. … Harms of thyroxine alone or thyroxine and triiodothyronine:
1. … Harms of antithyroid agents:
1. Antithyroid Drugs:
a. Mild temporary fever
b. … What are the harms of screening?
3. … What are the harms of screening?
3.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - has grown and a synthesis that
incorporates new evidence could improve estimates of the benefits and harms … Key Question 3: Harms. Collection of adverse events data was notably inconsistent
across studies. … Serious
harms were rarely reported, but some minor harms such as diarrhea and dizziness were
common … Neither
ondansetron nor prazosin had adequate data to assess harms. … For most serious harms, there was insufficient data to
determine comparative rates of adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - To Reduce Acute Pain in the Prehospital Setting
Purpose of Review
To evaluate effectiveness and harms … Summary of the comparative effectiveness and harms of initial analgesics in the
prehospital setting … Evidence of
harms was either insufficient or nonexistent.
Table C. … Summary of the comparative effectiveness and harms of subsequent analgesics
in the prehospital setting … In patients who
do not adequately respond to initial morphine,
comparative harms of giving ketamine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
November 02, 2019 - In addition,
awareness has grown regarding treatment benefits and harms relative to men’s
preferences … 6) Combination of above
KQ 2: How do patient characteristics modify comparative effectiveness and harms … It also shows harms that may
occur. … ; biopsy harms
(infection); ADT-related harms:
MACE, fractures, cognitive
impairment
Interventions … Systematic review: comparative
effectiveness and harms of treatments
for clinically localized prostate
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - short- (1 to <6 m), intermediate- (≥6 to <12 m), and long-term (≥12 m)
KQ 1-5 evaluated benefits and harms … of interest include kratom (focus on treatments with both potential analgesic effects and potential harms … In adults with chronic pain, what are the harms of cannabinoids for treatment of chronic pain? … In adults with chronic pain, what are the harms of kratom or other plant-based substances for treatment … acute treatments for episodic migraine exist with varying degrees of evidence for effectiveness and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
January 01, 2012 - We did not address harms of surgical interventions in
this review, as we felt that the studies meeting … intervention for CPP
would present only a partial picture of potential harms
of surgery. … In addition to
outcomes for treatment effectiveness, we extracted data
on harms/adverse effects. … Reporting of harms
data was very limited among trials; among placebo-
controlled trials, harms were more … • Few nonsurgical studies reported harms.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
April 01, 2021 - Preventive
Services Task Force1
What Are the Harms
Associated with
Pharmacotherapy? … What Are the Harms
of Screening for AF With
ECG in Older Adults? … What are the harms
of skin self-examination? … What
are the harms of screening
for adolescent idiopathic
scoliosis? … Effect and harms of
opioid switching/rotation
3. Comparison of opioid
formulations
4.
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Harms and adverse events:
– What are the risks of nonopioid
pharmacologic agents for harms including … Harms results are organized by drug
class. … Harms
Across all classes, incidence of serious adverse
event (SAEs) was low. … Forty good- or fair-
quality trials evaluated harms of antidepressants. … Seventy-nine trials evaluated harms of NSAID
treatment in the short term.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - The magnitude
of benefit and harms in contemporary
practice with the use of rigorous
endpoint definitions … established.2
Objectives
To perform a comparative effectiveness review examining
the benefits and harms … As
such, it is likely inferior to factor Xa inhibitors in the
balance of benefits and harms as well … The balance of benefits and harms from using enoxaparin
versus another low molecular weight heparin … Harms were not assessed in these
trials or observational studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - How could supply chain disruption monitoring programs prevent or mitigate
harms?
2. … devices, and supplies to patients and providers, potentially lowering
quality care and increasing harms … *_ga_1NPT56LE7J*MTcwMTc1MzIzMS4xODUuMS4xNzAxNzU0NzIyLjAuMC4w
3
Mitigating harms due to supply chain … Patients may experience a number of harms related to supply chain disruptions. … identify and describe how supply chain disruption monitoring programs (a) may
prevent or mitigate harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - : (1 new)
2b Harms in subgroups
2c Opioids vs. nonopioids
harms
2d Opioids + nonopioid vs. … Harms and Adverse Events:
a. … endocrinological harms, infections, cardiovascular events, cognitive harms,
and psychological harms … harms, infections, cardiovascular events, cognitive harms,
and mental health harms (e.g., depression … harms,
infections, cardiovascular events, cognitive harms, and mental health
harms (e.g., depression