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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - aggressive behaviors; changes in the
status of co-occurring disorders; ability to live independently; harms … other treatment options/variations (e.g., different dosage of the
same antipsychotic)
Outcome(s): Harms … What are the comparative benefits and harms of pharmacological treatments for
from Nominator: adults … time since illness onset, prior treatment history, co-occurring disorders)
predict the benefits and harms … time since illness onset, prior treatment history, co-occurring disorders)
predict the benefits and harms
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/my-nomination-is-about-comparing-outcomes-of-different-glaucoma-treatments-particularly-canaloplasty-to-trabeculectomy-and-to-medical-therapy-alone
November 23, 2008 - how well the test, treatment, or intervention works There is significant potential for side effects/harms … Screening or diagnosis/identification for a particular disease, or risk assessment for a disease Risks or harms … Management of a condition or particular system of care Delivery of a health service Referral Risks or harms … Harms: Are there risks, side effects, or harms you are concerned about?
-
effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-2007/research
November 19, 2007 - Evidence-based Practice Center summarizes the evidence on the comparative efficacy, effectiveness, and harms … For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in harms, tolerability … What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - • Research is needed to determine the benefits and harms of other interventional
procedures addressed … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic, clinical … Background and Purpose
The purpose of this systematic review is to evaluate the effectiveness and harms … Data on harms were relatively sparse and
inconsistently reported. … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic (age,
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-supplemental-oxygen.pdf
October 16, 2020 - no studies that addressed the first key question (KQ) regarding the comparative
effectiveness and harms … • We found only one study that addressed the second KQ regarding the comparative
effectiveness and harms … What is the comparative effectiveness and harms of oxygen devices in adults with
chronic lung disease … Effectiveness and harms of oxygen
prescribing practices
2. … Incorporates issues around both clinical
benefits and potential clinical harms
Yes.
2d.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary.pdf
September 01, 2021 - • Research is needed to determine the benefits and harms of other interventional
procedures addressed … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic, clinical … Background and Purpose
The purpose of this systematic review is to evaluate the effectiveness and harms … Data on harms were relatively sparse and
inconsistently reported. … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic (age,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - • Research is needed to determine the benefits and harms of other interventional
procedures addressed … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic, clinical … Background and Purpose
The purpose of this systematic review is to evaluate the effectiveness and harms … Data on harms were relatively sparse and
inconsistently reported. … ,
evaluate longer-term outcomes, and evaluate how benefits and harms according to
demographic (age,
-
effectivehealthcare.ahrq.gov/products/kidney-disease-medicine/research-protocol
July 28, 2010 - on both the benefits and harms of screening and early treatment. … We expanded and made the list of potential harms possibly associated with screening, monitoring, and/ … How do patient factors and CKD screening thresholds modify the association of CKD screening with harms … Does the presence of CKD modify the likelihood of harms associated with treatment of vascular disease … How do patient factors and CKD severity/stage modify the association of CKD treatment with harms?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - The USPSTF makes recommendations based on
the balance of benefits and harms; therefore, it requires … evidence on both the benefits
and harms of screening and early treatment. … Yet, there is little evidence regarding the benefits, harms,
and optimal frequency of monitoring kidney … • We expanded and made the list of potential harms possibly associated with
screening, monitoring … • How do patient factors and CKD severity/stage modify the association of CKD
treatment with harms?
-
effectivehealthcare.ahrq.gov/products/chronic-urinary-retention/research
September 15, 2014 - 18, 2014 Disposition of Comments Report Chronic Urinary Retention: Comparative Effectiveness and Harms … Evidence on harms was inconsistently reported across all interventions, and no differences were detected … across treatment groups; however, studies were not adequately powered to detect differences in harms
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-benefits-infants-children-key-questions.pdf
January 01, 2018 - What are the benefits and harms for infants and children among those who mostly
breastfeed, mostly formula … Do the harms and benefits differ for any specific subpopulations based on socio-
demographic factors? … feeding, breast milk feeding with maternal or banked
milk, formula feeding
KQ1: Benefits and Harms … milestones, and chronic
conditions
full-term or
pre-term
Infants and
children
KQ2: Benefits and Harms
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-and
March 11, 2008 - how well the test, treatment, or intervention works There is significant potential for side effects/harms … Screening or diagnosis/identification for a particular disease, or risk assessment for a disease Risks or harms … Management of a condition or particular system of care Delivery of a health service Referral Risks or harms … Harms: Are there risks, side effects, or harms you are concerned about?
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-effectiveness-of-interventions-intended-to-treat-anxiety-disorders-in-children-18-years-of-age-over-the-long-term-6-12-months-what-is-the-effectiveness-of-interventions-intended-to-prevent-the-development-of-anxie
March 07, 2013 - What are the harms of treatments for anxiety disorders in children? … if first line approaches are not effective
Describe any health-related risks, side effects, or harms … -Medication side effects -Unintended consequences/harms potentially associated with psychosocial, behavioral … evidence-based approaches to treatment and treatment choices; effects of treatment on comorbidities and harms … Understanding treatment effects and harms and instituting appropriate treatment can reduce morbidity
-
effectivehealthcare.ahrq.gov/decision-aids/lung-cancer-screening/static/lung-cancer-screening-clin-checklist.pdf
March 01, 2016 - potential benefits of lung cancer screening:
» Reduced mortality from lung cancer
Discussed potential harms … process for shared decisionmaking
that includes exploring and comparing the possible
benefits and harms … STEP 2: Help your patient explore and compare the
potential benefits and harms of lung cancer
screening … The harms associated with cumulative
radiation exposure are unknown.
» Screening should stop if the … There are also potential harms associated with lung cancer screening, including a high-false positive
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/lung-cancer-screening-clin-checklist.pdf
March 01, 2016 - potential benefits of lung cancer screening:
» Reduced mortality from lung cancer
Discussed potential harms … process for shared decisionmaking
that includes exploring and comparing the possible
benefits and harms … STEP 2: Help your patient explore and compare the
potential benefits and harms of lung cancer
screening … The harms associated with cumulative
radiation exposure are unknown.
» Screening should stop if the … There are also potential harms associated with lung cancer screening, including a high-false positive
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
September 02, 2013 - studies
Cohort and case-control studies
What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms
In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
September 02, 2013 - studies
Cohort and case-control studies
What Types of Observational Studies Are Best for Assessing Harms … What Types of Observational Studies Are Best for Assessing Harms
In the absence of sufficient trial … These studies should routinely be included in CERs for evidence of harms. … These studies should routinely be included in CERs for evidence of harms. … When assessing harms in comparative effectiveness reviews, investigators should routinely include cohort
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-key-question_0.pdf
January 01, 2019 - Draft Key Questions
Key Question 1: What is the effectiveness, comparative effectiveness, and harms … behaviors
Intermediate/process outcomes
• Adherence to medication
• Participation in treatment
Harms … of health
Questions Key Question 1: What is the effectiveness, comparative effectiveness, and
harms … Any harms: medication side effects, stigma
Timing All/any (short term, long term)
Figure 1.
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effectivehealthcare.ahrq.gov/products/treatments-acute-pain/protocol
January 02, 2020 - with respect to: (1) misuse, opioid use disorder, and related outcomes; (2) overdose; (3) other harms … harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … How do harms vary depending on: (1) patient demographics (e.g., age, gender); (2) patient medical or … harms, cardiovascular-related harms, kidney-related harms, falls, fractures, motor vehicle accidents … , endocrinological harms, infections, cognitive harms, and psychological harms (e.g., depression)?
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effectivehealthcare.ahrq.gov/products/appendicitis/research
December 14, 2015 - cohort studies that reported information on test accuracy for the diagnosis of acute appendicitis or harms … Only a few studies reported information on harms, leading to concerns about selective outcome reporting … Therefore, no definitive conclusions could be drawn about patient-relevant outcomes or harms. … limited to allow the identification of modifiers of test performance, patient-centered outcomes, or harms … modifiers; and to evaluate the impact of testing strategies on patient-relevant outcomes, resource use, and harms