-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - populations were studied, the detailed components of the treatment program, and the
health outcomes and harms … What are the potential safety issues and harms that may be associated with an MPP? … Potential Safety Issues or Harms
E. … Potential Safety Issues or Harms
Study Safety Issues or
Harms Assessed MPP Therapy Comparison
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Key Question
Key Question: What are the comparative benefits and
harms of different contrast media in … How do benefits or harms of contrast media differ by
patient characteristics (known risk factors such … How do benefits or harms differ by the
dose of contrast medium (i.e., by volume of dose and
number … How do benefits or harms of contrast media differ
according to the type of preventive strategy used? … We did not
find any studies that examined whether the benefits or
harms of contrast media differed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - What are the harms associated with prevention strategies?
c. … Question 3: What is the comparative effectiveness and harms of different antibiotic treatments?
a. … Question 4: What are the effectiveness and harms of non-antibiotic adjunctive interventions?
a. … environmental
cultures
Days to resolution of
diarrhea (choice of faster
working treatment)
Harms … Treatment of false
positives
Increased
resistance
Isolation harms
Prevention
Patient Specific
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - resulted in contradictory conclusions and
recommendations regarding the comparative effectiveness and harms … determined that increasing comprehensiveness by reviewing all possible observational studies that present harms … the strength of the
body of evidence to answer KQs on the comparative effectiveness, efficacy, and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
April 01, 2016 - Harms due to overtreatment or undertreatment
e. Survival
f. Quality of life
KQ 3. … the choice
of test (or test strategy) might influence choice of
treatment, timeliness of treatment, harms … • For comparative harms of over- or undertreatment
(part of KQ2), this means reporting the percentage
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
July 09, 2014 - Comparative effectiveness reviews evaluate the evidence for both benefits and harms,
or adverse effects … In the case of cultural competence interventions, harms may include
unintended consequences of an intervention … Studies specifically addressing treatment harms may also include retrospective
and case series designs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
April 01, 2016 - questions
address what the end-user needs,
including clinical outcomes and
consideration of benefits and harms … guideline developer) felt that the
rapid review was limited in terms of the spectrum of benefits and harms … "
KIs commented on the fact that there is generally more than the evidence of benefits
and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
January 08, 2025 - event data were collected actively
(e.g., all participants were asked about the occurrence of specific harms … Quality Assessment Scale for
adverse events: Delphi Consensus on important criteria for evaluating harms … AHRQ series paper 4: assessing harms when
comparing medical interventions: AHRQ and the effective health-care
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
June 10, 2024 - event data were collected actively
(e.g., all participants were asked about the occurrence of specific harms … Quality Assessment Scale for
adverse events: Delphi Consensus on important criteria for evaluating harms … AHRQ series paper 4: assessing harms when
comparing medical interventions: AHRQ and the effective health-care
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - interventions yield small to moderate effects, and
the benefits must be weighed against the potential harms … Because only limited data on harms were reported in the
trials examined, data from non-SMI populations … Quasi-experimental or clinical records-based
observational studies
Limited evidence about the benefits
and harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/advanced-care-decision-aids_research-protocol.pdf
December 09, 2013 - Were harms or adverse effects collected in the studies; what were they?
f. … What comparators were used to examine benefits and harms?
4. … different populations (possibly by study design)
Decision Clinical Inclusion Exclusion Sample Comparator Harms … (ethical/
Aid/Use population/ criteria- criteria size/Study emotional
design harms) General
Table
-
effectivehealthcare.ahrq.gov/products/collections/making-healthcare-safer-IV
-
effectivehealthcare.ahrq.gov/products/insomnia/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Few studies on harms lasted longer than 2 years. … The FDA approval process focuses on short-
term harms, providing less incentive for pharmaceutical
companies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - unintended consequences
(e.g., decrease in levels of indicated care for non-priority conditions) or other harms … In addition, the association of PCMH with
unintended consequences or other harms is demonstrated.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
December 01, 2011 - For harms we also included large uncontrolled
studies. … Some sections are
synthesized well (KQ1 and also harms), while others are not quite
there yet (KQ 2
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - However, it is not clear whether the diagnostic accuracy or the relative balance of
benefits and harms … studies addressing
prognostic/risk stratification, predictors of accuracy, cardiovascular outcomes, and
harms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - Immunoglobulin E (IgE)
§ Allergen-specific Immunoglobulin G4 (IgG4)
Outcomes for Key Questions 2 and 4
o Harms … For key questions 2 and 4 we will grade harms: anaphylaxis, hypersensitivity adverse effects and
death
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
July 29, 2014 - Peer Reviewer #4 Findings Study Designs: When discussing potential harms of decision
aids, the authors … We
have changed the language in that section and
added the need to consider how harms should
be conceptualized
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
March 01, 2012 - Peer Reviewer #3 Abstract I tend to see things a bit differently: benefits do not outweigh
harms in