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Showing results for "harms".

101. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - This systematic review assesses the comparative effectiveness and harms of PBI compared with WBI for … cm that has minimal or no lymph node involvement (N0/1), and how differences in effectiveness and harms … Comparative Effectiveness and Harms of PBI Versus WBI Thirteen RCTs reported in 38 articles with a … total of 15,276 patients were included in the assessment of the comparative effectiveness and harms … of PBI Versus WBI Comparative Effectiveness and Harms of PBI Modalities Financial Toxicity Related

102. Management of Primary Headache During Pregnancy: Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
     March 23, 2019 - Specifically, the review will address: (1) the (comparative) benefits and harms of pharmacologic and … o For harms, we will also search the U.S. … o For harms, we will also search the U.S. … We expect to summarize harms data semi-quantitatively (i.e., without meta-analysis). … We expect to primarily rely on reported within-study differences in effects (or harms).

103. Cancer-Ovarian-Contraceptives Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
     June 01, 2013 - Also, because the majority of evidence on noncontraceptive benefits and harms of OC use is derived from … 3 KQ 5: What are the harms of OC use, including breast cancer incidence, cervical cancer incidence … How do these harms vary by dose or formulation, duration of use, or specific population? … KQ 6: Based on the comprehensive literature review, what are the benefits and harms from the use of … For incident harms and benefits, the likelihood that benefits outweighed harms was less than 40 percent

104. Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
     December 18, 2019 - 1a: How do effectiveness and harms vary by choice of prostaglandin? … • Include high quality cohort and case-control studies for harms. … • Include high quality cohort and case- control studies for harms. … • Include high quality cohort and case- control studies for harms. … • Include high quality cohort and case-control studies for harms.

105. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - Assessing the Risk of Bias for Harms Although the assessment of harms is almost always included as an … Although reviewers recognize the importance of harms outcomes, harms are generally ignored in risk-of-bias … The McMaster University Harms scale (McHarm) was developed specifically for evaluating harms and is … Was the mode of harms collection specified as ACTIVE? 6. … Did the study specify WHO collected the harms? 8.

106. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - ...................... 3 Integrated and Comprehensive Pain Management Programs: Effectiveness and Harms … • Although evidence was limited, serious harms were not reported for either program. … • Longitudinal studies on opioids to evaluate longer- term outcomes, including associated harms ( … They should also collect data on psychological and other harms of cognitive testing. … outcomes; should plan a priori to examine possible effect modifiers of harms outcomes.

107. Nonsurgical Treatments for Urinary Incontinence in Adult Women: (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
     June 06, 2017 - What are the harms from nonpharmacological treatments when compared with no active treatment? … What are the comparative harms from nonpharmacological treatments when compared with each other? … What are the harms from pharmacological treatments when compared with no active treatment? 2c. … What are the comparative harms from pharmacological treatments when compared with each other? … KQ 4: What are the benefits and harms of combined nonpharmacological and pharmacological treatment

108. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - How are patient factors related to the harms of different imaging techniques? b. … For KQ3 on the rates of procedural harms, we included any reported harms data based on 50 or more patients … – For harms (KQ3), this means a statement appearing in the Methods section that harms/complications … We did not grade the strength of evidence for harms. … , the harms of concern are different for different tests.

109. The Performance of Fusion Procedures for Degenerative Disease of teh Lumbar Spine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-protocol.pdf
     June 20, 2024 - What are the benefits and harms of surgery with instrumentation in addition to decompression compared … What are the benefits and harms of the use of bone graft extenders and biologic substitutes compared … only and must be specifically designed to evaluate/report on AE/harms and control for confounding … and focused on rare or long-term harms. … Integrated and Comprehensive Pain Management Programs: Effectiveness and Harms.

110. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - This trial had low risk of bias, and harms were well monitored and reported. … How do the harms compare across different interventions? … Harms for interventions for both adults and adolescents were predominately derived from RCTs. … This trial had low risk of bias, and harms were well monitored and reported. … How do the harms compare across different interventions?

111. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - must be balanced against the potential harms to mother and fetus of untreated depression. … Objectives The objective of this systematic review was to evaluate the benefits and harms of various … What are the comparative harms of pharmacological and nonpharmacological treatments for women with … Child Harms Evidence on harms to the child of a mother treated for depression during pregnancy was limited … These studies contributed to the evidence on potential harms with treatment during pregnancy.

112. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
     July 06, 2015 - systolic function and are receiving standard medical therapy, what is the evidence of comparative harms … What is the evidence that benefits or harms differ by subpopulations, including: demographics [sex, … therefore a similar balance of benefits to harms. … Since there were no subgroup comparisons based on harms, the balance of benefits to harms in these … Since there were no subgroup comparisons based on harms, the balance of benefits to harms in these

113. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
     April 01, 2022 - : 102 studies (1 new) 2b Harms in subgroups: 18 studies (2 new) 2c Opioids vs. non-opioids harms: … Harms and Adverse Events: a. … endocrinological harms, infections, cardiovascular events, cognitive harms, and psychological harms … harms, infections, cardiovascular events, cognitive harms, and mental health harms (e.g., depression … harms, infections, cardiovascular events, cognitive harms, and mental health harms (e.g., depression

114. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
     January 01, 2008 - NSAIDs (these are rarely used alone and have no disease-modifying properties)) Outcome(s): Potential harms … For children with juvenile idiopathic arthritis, do drug therapies differ in harms, tolerability, adherence … What are the comparative benefits and harms of drug therapies for juvenile idiopathic arthritis in

115. Deprescribing To Reduce Medication Harms in Older Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/deprescribing-mhs4/rapid-research

116. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - When referring to harms, especially in relation solely to clinical harms, it is critical to take into … The purpose of the citations is to provide context regarding concerns about harms and we think it … We agree, which is why the focus is on long-term benefits and harms. … Short- term benefits and harms have been fairly well delineated in placebo- controlled RCTs. … There are indeed many kinds of harms, so we preserved this language.

117. Radiation Therapy for Bone Metastases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
     August 10, 2022 - The 2017 guideline did not explicitly address the benefits and harms of therapies used in addition to … Harms associated with the combination of therapies is of particular concern. … For evaluation of harms, we will include comparative cohort and case-control studies with a focus on … those specifically designed to evaluate harms. … Integrated and Comprehensive Pain Management Programs: Effectiveness and Harms.

118. Cervical Degenerative Disease Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
     January 12, 2022 - , especially long-term harms (e.g., arthroplasty); and (9) determining which outcomes to assess and … How do the effectiveness and harms vary by level of severity of myelopathy at the time of surgery? … In patients with cervical degenerative disease, what are the comparative effectiveness and harms of … In patients with cervical degenerative disease, what are the comparative effectiveness and harms of … Nonrandomized, controlled studies of interventions will also be considered for harms.

119. Moyer_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
     January 01, 2012 - studies, but reviews and  assesses existing   research o Evaluates the balance of benefits and harms … when the evidence is insufficient in quality or quantity Slide 4: Balance  of Benefits  and Harms … Benefits – Harms = Net Benefit Source: Eisenberg Center Conference Series 2012: Supporting  Informed … There is moderate or hig certainty  that the  service has no net benefit or that the harms outweigh … USPSTF concludes  that current evidence is insufficient to  assess the balance of benefits and harms

120. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - recommended for people with physical disabilities,2 less is known about the specific benefits and potential harms … Key Question 2: Benefits and Harms Compared with no physical activity or usual care, physical activity … cer-methods-guide/overview 3 Key Question 3: Patient Factors Affecting Benefits and Harms … Question 1: Prevention of Cardiovascular Conditions, Diabetes, and Obesity Key Question 2: Benefits and Harms … Key Question 3: Patient Factors Affecting Benefits and Harms Limitations Key Question 4: Methodological