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Showing results for "harms".

81. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/alzheimers-type-dementia/protocol
    August 01, 2020 - Identification of patient characteristics that are associated with diagnostic test accuracy and harms … , and with pharmacological treatment efficacy and harms may help physicians, patients and caregivers … Table 1 All harms outcomes were in one list. … Categorized harms outcomes as general, psychiatric, and nonpsychiatric. … This change to categorize harms outcomes was made for clarification.

82. Should subclinical hypothroidism be treated? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
    November 01, 2017 - well the test, treatment, or intervention works   There is significant potential for side effects/harms … or diagnosis/identification for a particular disease, or risk assessment for a disease   Risks or harms … a condition or particular system of care   Delivery of a health service   Referral   Risks or harms … Harms: Are there risks, side effects, or harms you are concerned about? … What are the benefits and harms of treating patients with subclinical hypothroidism vs watchfull waiting

83. Evidence Summary: Comparative Effectiveness Review No. 238: Cervical Ripening (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
    March 01, 2021 - and Purpose The purpose of this review is to assess the comparative effectiveness and potential harms … majority of the evidence (22 RCTs, 1 cohort study) pertained to the comparative effectiveness and harms … Primary fetal harms outcomes Key Question Intervention Outcome Findingsa Studies Incidence Relative … Differences in rare harms, such as hypoxic-ischemic encephalopathy, would require much larger studies … , although not all such harms were adequately studied.

84. Management of Colonic Diverticulitis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diverticulitis/protocol
    October 01, 2019 - What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. … Harms of over-treatment (due to false positive findings; e.g., surgery, stress) Harms of under-treatment … We expect to summarize harms data semiquantitatively (i.e., without meta-analysis). … For Key Question 3, we will focus on event rates of the clinical outcomes and harms. … We expect to primarily rely on reported within-study differences in effects (or harms).

85. Cervical Degenerative Disease Treatment: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/research
    February 01, 2024 - of evidence was rated low or insufficient strength to draw conclusions on comparative benefits and harms … What are the comparative effectiveness and harms of therapies added on to surgery (pre- or post-operative … (low SOE ) Reoperation: Similar (low SOE )             What are the comparative effectiveness and harms … for cervical degenerative disease (CDD), as well as how effectiveness and harms may differ by patient … In patients with pseudarthrosis after ACDF, evidence on comparative effectiveness and harms of revision

86. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
    January 01, 2019 - What are the procedure-related and other harms of colonoscopy or CT colonography? … o Harms of over-treatment (due to false positive findings; e.g., surgery, stress) 6 o Harms … We expect to summarize harms data semiquantitatively (i.e., without meta-analysis). … For Key Question 3, we will focus on event rates of the clinical outcomes and harms. … We expect to primarily rely on reported within-study differences in effects (or harms).

87. Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoarthritis-pain/research
    December 01, 2019 - Structured Abstract Objectives To update a previous report on the comparative benefits and harms … , nonaspirin NSAIDs appeared to be associated with an increased risk of serious cardiovascular (CV) harms … clear association between longer duration of NSAID use or higher doses and increased risk of serious CV harms … gastrointestinal (GI) adverse events, and higher risk of dermatological adverse events, but serious GI and CV harms

88. App-F2-Surv-Report-3-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
    September 20, 2022 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of serotonin–norepinephrine reuptake inhibitor versus placebo Author, Year Quality Pain Population … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time

89. Prehabilitation and Rehabilitation for Major Joint Replacement | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/major-joint-replacement/research
    October 01, 2022 - Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … No studies addressed the risk of harms due to rehabilitation delivered in the acute phase after TKA. … Compared with various controls, there was no evidence of an increased risk of harms due to more active … There was no evidence of an increased risk of harms due to prehabilitation (low SoE). … There is some evidence of no increased risk of harms due to the intervention (low SoE).

90. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … harms, infections, cardiovascular events, cognitive harms, and mental health harms (e.g., depression … harms, infections, cardiovascular events, cognitive harms, and mental health harms (e.g., depression … Harms of opioids vs. … Harms of opioids vs.

91. Screening for and Management of Chronic Kidney Disease Stages 1-3 | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/kidney-disease-medicine/research-protocol
    December 01, 2019 - on both the benefits and harms of screening and early treatment. … We expanded and made the list of potential harms possibly associated with screening, monitoring, and/ … How do patient factors and CKD screening thresholds modify the association of CKD screening with harms … Does the presence of CKD modify the likelihood of harms associated with treatment of vascular disease … How do patient factors and CKD severity/stage modify the association of CKD treatment with harms?

92. AHRQ EPC Program Research Gaps Summary: Women's Health (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/research-gaps-womens-health-22.pdf
    April 01, 2022 - ; a systematic review will help clarify the balance of benefits and harms. … Outcomes • More high-quality studies on harms of pharmacotherapy. … • Systematic reviews of harms (regardless of indication) report that acetaminophen, prednisolone … o Serious harms were not observed with the interventions. … Outcomes • Potential harms related to breastfeeding interventions.

93. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … including gastrointestinal-related harms, cardiovascular-related harms, kidney-related harms, falls … , fractures, motor vehicle accidents, endocrinological harms, infections, cognitive harms, and psychological … harms (e.g., depression)? … Misuse, opioid use disorder, overdose and other harms KQ 2.

94. Update Topic CER 31 Clostridium difficile NSD FINAL (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - (b) What are the harms associated with prevention strategies? … characteristics § Resistance of other pathogens Key Question 4: What are the effectiveness and harms … § What are the harms associated with prevention strategies? … What are the comparative effectiveness and harms of different antibiotic treatments? … What are the effectiveness and harms of nonstandard adjunctive interventions?

95. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
    January 01, 2011 - In addition, they question whether the benefits and harms of these tests vary by the risk of the surgical … testing or alternative testing Outcome(s): Surgical complications, morbidity, mortality, patient delays, harms … What are the harms of routine preoperative testing compared to no testing or to an alternative testing … Do the benefits or harms of routine preoperative tests vary by the risk of the surgical procedure (low … Do the benefits or harms of routine preoperative tests vary by the clinical conditions, comorbidities

96. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
    January 01, 2010 - Nomination Summary: The nominator is interested in the comparative maternal and fetal benefits and harms … For pregnant women or women receiving preconception care with depression, what are the comparative harms … Potential harms and benefits of depression treatment must be weighed against the potential harms of … an evidence-based product for clinicians and patients that addresses the comparative benefits and harms

97. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
    January 01, 2008 - professional association Nomination Summary: The nominator is interested in the benefits and harms … What are the benefits and harms of treating patients with subclinical hypothyroidism vs. watchful waiting … What are the potential harms from treatment and non-treatment? … What are the harms of screening? 4. … What are the harms of treatment of sub-clinical hypothyroidism and sub-clinical hyperthyroidism?

98. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
    July 01, 2023 - What is the frequency and severity of harms addressed by the patient and family engagement PSPs? … What measures or indicators have been used to examine the harms associated with the target of the patient … What patient and family engagement PSPs have been used to prevent, report, or mitigate harms to patients … for the patient and family engagement PSPs that have been used to prevent, report or mitigate the harms … What is the frequency and severity of harms addressed by the patient and family engagement PSPs?

99. Efficacy and Safety of Screening for Postpartum Depression | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/depression-postpartum-screening/research
    December 01, 2019 - Structured Abstract Objectives To describe the benefits and harms of specific tools and strategies … evaluated the performance of screening instruments for postpartum depression, potential benefits and harms … estimate the effects of screening for postpartum depression on the overall balance of benefits and harms … Because the balance of benefits and harms, at both the individual level and health system level, is highly

100. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ems-blood-transfusion/protocol
     February 01, 2025 - First, we will assess the effectiveness and potential harms of different blood transfusion and fluid … What are the comparative benefits and harms of low-titer group O whole blood transfusion compared with … What are the comparative benefits and harms of low-titer group O whole blood transfusion compared with … What are the comparative benefits and harms of component blood therapy transfusion compared with fluid … Are the benefits and harms modified by: EMS protocol (including but not limited to transfusion volume