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Showing results for "harms".

61. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
    May 01, 2017 - High SOE for clinically significant harms associated with risperidone Harms including weight gain … High SOE for clinically significant harms associated with aripiprazole Harms including weight gain … Low SOE for minimal harms No clinically significant harms reported in any study N-acetylcysteine … Low SOE for minimal harms No study reported harms considered clinically important Table B. … Harms reporting varied across studies; some studies amply described how harms were tracked, while others

62. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
    January 01, 2008 - effects of treating older patients with antipsychotics and requests information on the benefits and harms … ), do the typical and atypical antipsychotic drugs differ in benefits (efficacy, effectiveness) or harms … schizophrenia, do the atypical antipsychotic drugs differ in benefits (efficacy, effectiveness) or harms … , do the typical and atypical antipsychotic drugs differ in benefits (efficacy, effectiveness) or harms … review from the EHC Program focus on key long-term, real life effectiveness trials and comparative harms

63. Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/kidney-disease-medicine/research
    December 01, 2019 - Objectives The objective was to systematically review and synthesize evidence regarding benefits and harms … We reviewed RCTs and observational studies for evidence regarding possible benefits and harms of CKD … Evidence on the benefits and harms of CKD treatments was quantitatively synthesized when possible. … screening and monitoring measures for CKD, and insufficient evidence on CKD screening and monitoring harms … Screening and monitoring harms are poorly described.

64. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/depression-pregnancy-postpartum/research
    December 01, 2019 - Structured Abstract Objectives To evaluate the benefits and harms of pharmacological therapy for … Outcomes included both maternal and infant or child benefits and harms. … Results We included 15 observational studies that provided direct evidence on benefits and harms of … This evidence was insufficient to draw conclusions on the comparative benefits or harms of antidepressants … Conclusions Evidence about the comparative benefits and harms of pharmacological treatment of depression

65. Management of Postpartum Hemorrhage | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hemorrhage-postpartum/research
    December 01, 2019 - evidence addressing the management of postpartum hemorrhage (PPH), including evidence for the benefits and harms … We also included case series addressing harms of interventions and benefits and harms of procedures and … Fifty studies reported harms of interventions for PPH management: 11 good quality and 39 poor. … Harms of interventions were diverse and not well understood.

66. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
    October 05, 2018 - Osteoporosis treatment harms vary by drug class. … >100 subjects for rare harms and >1000 subjects for other harms KQ 5: Effect of drug treatment … Timing Setting Study Design KQ 7: Harms of drug treatment holidays KQ8: Predictors of harms … >100 subjects for rare harms and >1000 for other harms Abbreviations: ALP = alkaline phosphatase … ) • Harms (Serious adverse events and specific harms as listed in Table 2) Outcome predictors (

67. What do we know about how evidence of harm and benefit is communicated in other countries? (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
    January 01, 2005 - Explicit approach to translation of evidence (but not rating of strength) Explicit description of harms … (not available for review) Approach to translating evidence not described Included description of harms … How does product discuss strength of evidence about benefits and/or harms? … NZGG: HRT—New Information for Women Appropriate Audience Compare Alternatives Benefits and Harms … Pain Guidelines Group: Acute Low Back Pain Appropriate Audience Compare Alternatives Benefits and Harms

68. Strategies to Improve Mental Health Care for Children and Adolescents | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/mental-health-children/research
    March 01, 2020 - dissemination strategies that seek to improve the mental health care of children and adolescents; to examine harms … associated with these strategies; and to determine whether effectiveness or harms vary in subgroups … Results We found 17 studies testing overall effectiveness of 16 strategies, of which 1 reported on harms … We were unable to judge the overall potential for harms associated with these strategies that may mitigate … benefits based on the single included study with information on harms.

69. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/mental-health-pregnancy/research
    March 01, 2022 - conducted in pregnant and postpartum women on the benefits of pharmacotherapy; many studies report on harms … The paucity of evidence does not mean that pharmacotherapy is not beneficial, nor that harms do not exist … whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms … We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared … We found insufficient evidence on benefits and harms from comparative effectiveness studies, with one

70. Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoporosis-fracture-prevention/research-protocol
    May 01, 2019 - Osteoporosis treatment harms vary by drug class. … harms of osteoporosis drug treatment holidays. … Predictors of of osteoporosis drug treatment holidays on incident fractures and harms. … Nonrare harms: Sample size must be ≥1000 and limited to prospective cohort studies. … Harms (Serious adverse events and specific harms as listed in Table 2 ) Outcome predictors (applicable

71. Protocol for Quantitative Assessment of Benefit and Harm analysis of Aspirin for primary prevention (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
    February 01, 2014 - analysis of Aspirin for primary prevention Methods Research Report Evaluation of the Benefits and Harms … Methods Research Report Evaluation of the Benefits and Harms … We were unable to account for joint distribution of benefits and harms. … We were unable to account for joint distribution of benefits and harms. … that benefits exceed harms.

72. Noninvasive Treatments for Low Back Pain | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/research
    December 01, 2019 - This review examines the evidence on the comparative benefits and harms of noninvasive treatments for … various physical modalities) for nonradicular or radicular low back pain that addressed effectiveness or harms … Trials were not designed or powered to detect serious harms from pharmacological therapies. … Although rates appeared to be low and there was not an increased risk of serious harms versus placebo … For nonpharmacological therapies, assessment of harms was suboptimal, but serious harms appeared to be

73. Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients During Clinical Care | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/clinical-care/rapid-research
    April 01, 2025 - SHARE: Making Healthcare Safer IV: Programs for Responding to Harms … Programs for Responding to Harms Experienced by Patients During Clinical Care. Rapid Review. … Project Timeline Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients … Rapid Evidence Product: Making Healthcare Safer IV: Programs for Responding to Harms

74. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
    November 01, 2020 -  A single primary study provided insufficient (direct) evidence to make conclusions about the harms … The uncertainty about the comparative effectiveness and harms of various treatment options underscores … ; fetal/child harms were not reported. …  No indirect evidence regarding harms of nonpharmacologic interventions in pregnancy was identified … For additional information on harms, we also searched for relevant SRs of interventions in women in

75. Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/acute-pain-ems/research
    January 01, 2022 - Purpose of Review To evaluate effectiveness and harms of opioids compared to nonopioid analgesics as … To assess comparative effectiveness and harms of opioid and nonopioid analgesics administered by emergency … Evidence on comparative effects of nitrous oxide and on harms of combined opioid and ketamine is insufficient … quicker than giving additional IV morphine (low SOE, insufficient evidence to determine comparative harms … provide greater and quicker acute pain relief than giving additional morphine, although comparative harms

76. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND__0355_09-22-2010.pdf
    January 01, 2010 - Anonymous individual Nomination Summary: The nominator questions the comparative effectiveness and harms … to another insomnia intervention Outcome(s): Quality of life, sleep quality, fatigue, and harms … For patients with insomnia, how do commonly used medications compare for effectiveness and harms, including … Insomnia can be associated with various harms, including decreased quality of life, cognitive deficits … A review on this topic will help to compare the relative benefits and harms of these interventions.

77. App-F2-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
    September 20, 2022 - Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug … Harms of pregabalin versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of pregabalin CR versus IR Author, Year Quality Pain Population Drug Class Drug Assessment Time … Harms of cannabis versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk) Time … Harms of lidocaine patch versus placebo Author, Year Quality Pain Population Drug Assessment Time (Wk

78. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
    April 01, 2020 - - Evidence Summary Purpose of Review The purpose of the review is to examine the benefits and harms … base, in order to capture the potential for a signal of harms. … With high risk-of-bias studies, the evidence suggests increased risk of harms. … Fourth, psychotherapy studies rarely reported on harms. … No evidence on harms of psychotherapy was identified. References 1.

79. Intergrated and Comprehensive Pain Management Programs: Effectiveness and Harms: Evidence Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
    October 01, 2021 - Intergrated and Comprehensive Pain Management Programs: Effectiveness and Harms: Evidence Summary Comparative … Review Number 251 Integrated and Comprehensive Pain Management Programs: Effectiveness and Harms … Our review assesses the effectiveness and harms of pain management • Integrated pain management programs … • Although evidence was limited, serious harms were not reported for either program. … Integrated and Comprehensive Pain Management Programs: Effectiveness and Harms.

80. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - , and with pharmacological treatment efficacy and harms may help physicians, patients and caregivers … 5 KQ3b: In adults with CATD, what are the comparative effectiveness and harms of prescription … Table 1 All harms outcomes were in one list. … Categorized harms outcomes as general, psychiatric, and nonpsychiatric. … This change to categorize harms outcomes was made for clarification.