Results

Total Results: 2,181 records

Showing results for "harms".

121. S16 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s16.pdf
     October 01, 2007 - Harms are variably and often poorly reported; TABLE 1. … Do benefits exceed harms in trials? … Will expected benefits exceed harms for me? … Can we similarly apply harms estimates from WHS? … Do benefits of CEA outweigh harms in trials?

122. Opioid Treatments for Chronic Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/opioids-chronic-pain/protocol
     May 01, 2020 - ; some harms (including overdose risk) were dose-dependent. … Harms and Adverse Events a. … harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … (including overdose, substance use disorder and misuse; other harms (including gastrointestinal harms … , cognitive harms, and psychological harms, including depression and suicidality).

123. Opioid Treatments for Chronic Pain Research Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
     December 19, 2018 - ; some harms (including overdose risk) were dose-dependent. … Harms and Adverse Events a. … harms, infections, cardiovascular events, cognitive harms, and psychological harms (e.g., depression … (including overdose, substance use disorder and misuse; other harms (including gastrointestinal harms … , cognitive harms, and psychological harms, including depression and suicidality).

124. Disposition of Comments: CER 234 Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-revised-comments.pdf
     November 12, 2020 - The EPC had inadvertently excluded a systematic review of indomethacin and its harms in pregnant women … overall, and paucity of studies in postpartum and breastfeeding women), contextual issues, and known harms … Reviewers suggested reorganizing the report such that the direct evidence (primary studies of benefits and harms … ) and indirect evidence (systematic reviews of harms) appear together in the same section for each intervention

125. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
     October 01, 2009 - What is the evidence that benefits or harms differ by subpopulations, including: demographics [sex, age … The ACE inhibitor ramipril and the ARB telmisartan have similar efficacy, similar risks of harms, and … therefore a similar balance of benefits to harms. … Given the lack of significant benefits found in Key Question 3, the balance of benefits to harms for … Since there were no subgroup comparisons based on harms, the balance of benefits to harms in these subgroups

126. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antipsychotics-children-update/research-2017
     April 01, 2020 - Purpose of Review To assess the effectiveness and harms of first- and second-generation antipsychotics … Harms across conditions : From network meta-analysis, olanzapine was more harmful for gains in weight … some extent key intermediate outcomes for which they are usually prescribed, but they have a poorer harms … priorities for research are long-term comparative effectiveness and development of systems for monitoring harms … Systematic Review Aug 29, 2023 Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms

127. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
     December 01, 2020 - Evidence about harms is also unclear. … They need information about the comparative effectiveness and harms of alternative therapies to the … This systematic review assesses the comparative effectiveness and harms for acute migraine treatments … Effectiveness and harms: • Tramadol in combination with acetaminophen may reduce pain at 2 hours and … trials evaluate the efficacy and harms of the treatments during one or a few attacks.

128. Disposition of Comments: CER 224, Treatment of Depression in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
     April 10, 2020 - on harms. … on harms. … on harms. … profound harms of untreated depression. … on harms.”

129. Evidence Summary_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
     November 01, 2021 - o Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … • Rehabilitation for Total Knee Arthroplasty (continued) o No studies addressed the risk of harms … o No studies compared prehabilitation to no rehabilitation on satisfaction with care or risk of harms … Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … We found no evidence regarding harms from acute-phase rehabilitation.

130. Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/arthritis-psoriatric/research
     December 01, 2019 - Structured Abstract Objectives To compare the benefits and harms of corticosteroids and oral and … least 100 participants, and relevant good- or fair-quality meta-analyses that compared benefits or harms … Observational studies were included only for harms. … Evidence was insufficient to draw conclusions about the comparative harms for oral DMARDs. … and the evidence is insufficient to draw firm conclusions on comparative efficacy, effectiveness, and harms

131. Terbutaline Pump for the Prevention of Preterm Birth | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preterm-birth-terbutaline-pump/research
     December 01, 2019 - Objectives To compare the benefits and harms of the SQ terbutaline pump with other tocolytics, conservative … We included noncomparative studies only for pump-related harms. … Absent or inconclusive evidence addressed all other neonatal health outcomes, neonatal harms, maternal … harms, and pump-related outcomes. … While postmarketing surveillance has detected cases of serious harms, safety of the therapy remains unclear

132. TND-0775-150722 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
     May 12, 2015 - aggressive behaviors; changes in the status of co-occurring disorders; ability to live independently; harms … other treatment options/variations (e.g., different dosage of the same antipsychotic) Outcome(s): Harms … What are the comparative benefits and harms of pharmacological treatments for from Nominator: adults … time since illness onset, prior treatment history, co-occurring disorders) predict the benefits and harms … time since illness onset, prior treatment history, co-occurring disorders) predict the benefits and harms

133. Prehospital Airway Management | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prehospital-airway-management/research
     August 01, 2021 - Main Points Four Key Questions addressed the comparative benefits and harms … To assess the comparative benefits and harms across three airway management approaches (bag valve mask … intubation [ETI]) by emergency medical services in the prehospital setting, and how the benefits and harms … While harms were not always measured or reported, moderate SOE supported all available findings. … There were no differences in harms for BVM versus SGA or ETI.

134. Medical Therapies for Children with Autism Spectrum Disorder — An Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/asd-medical/research-2017
     January 01, 2021 - improvements in challenging behavior in the short term (< 6 months) but also clinically significant harms … nutritional supplements or specialized diets, evidence is insufficient for all clinical efficacy and harms … Methylphenidate was associated with clinically significant harms (low SOE), while atomoxetine was associated … with clinically moderate harms (low SOE). … growing number of RCTs and use of standardized measures), data on longer term (≥6 months) results and harms

135. Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/rheumatoid-arthritis-2007/research
     December 01, 2019 - Evidence-based Practice Center summarizes the evidence on the comparative efficacy, effectiveness, and harms … For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in harms, tolerability … What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic … Systematic Review Aug 29, 2023 Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms

136. Evidence Summary_Comparative Effectiveness Review No. 247_Interventional Treatments for Acute and Chronic Pain: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
     September 01, 2021 - • Research is needed to determine the benefits and harms of other interventional procedures addressed … , evaluate longer-term outcomes, and evaluate how benefits and harms according to demographic, clinical … Background and Purpose The purpose of this systematic review is to evaluate the effectiveness and harms … Data on harms were relatively sparse and inconsistently reported. … , evaluate longer-term outcomes, and evaluate how benefits and harms according to demographic (age,

137. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
     November 01, 2010 - The USPSTF makes recommendations based on the balance of benefits and harms; therefore, it requires … evidence on both the benefits and harms of screening and early treatment. … Yet, there is little evidence regarding the benefits, harms, and optimal frequency of monitoring kidney … • We expanded and made the list of potential harms possibly associated with screening, monitoring … • How do patient factors and CKD severity/stage modify the association of CKD treatment with harms?

138. Interventions for Breathlessness in Patients With Advanced Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dyspnea-advanced-cancer/report
     February 01, 2021 - To assess benefits and harms of nonpharmacological and pharmacological interventions for breathlessness … controlled trials (RCTs) and observational studies with a comparison group evaluating benefits and/or harms … , and cohort studies reporting harms. … Opioids, bilevel ventilation, and activity/rehabilitation interventions had some harms compared to usual … More research is needed on when the benefits of opioids may exceed harms for broader, longer term outcomes

139. Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cancer-pancreas/research
     December 01, 2019 - specificity), staging accuracy, screening accuracy, clinical management, quality of life, survival, and harms … For studies of a single imaging test, the key outcomes were accuracy and procedural harms. … For data on single-test accuracy, procedural harms, patient tolerance, and screening accuracy, we tabulated … Many studies have reported procedural harms, but harms are generally rare and are different for different

140. Benefits and Harms of Routine Preoperative Testing: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preoperative-testing
     March 01, 2021 - SHARE: Benefits and Harms … Page originally created December 2020 Internet Citation: Benefits and Harms