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effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
September 01, 2014 - Even when used under
medical supervision, these products can cause serious harm,
including dehydration
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effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_vulnerable_populations_kreps.ppt
May 29, 2025 - No Slide Title
Communicating Harm and Benefits to Vulnerable Populations
Gary L. Kreps, Ph.D.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - Evidence Summary for CER 239: Acute Treatments for Episodic Migraine
Comparative Effectiveness Review
Number 239
Acute Treatments for Episodic Migraine
Evidence Summary
Main Points
• Compared with placebo, treatments such as triptans, NSAIDs (nonsteroidal anti-
inflammatory drugs), dihydroergotamine, antieme…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - Outcome measures related to pain, function, various types of harm, etc. … The assumption is that there are many different kinds of harm. … It would be useful to
briefly describe why this term was used rather than the more familiar “harm.” … that the use of methadone as a pain therapy is
associated with a disproportionate share of patient harm … However, the scope and
nature of this harm is not fully described in the report.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
May 08, 2023 - intervention related to a drug”.1, 2 Adverse drug events are a leading type of
healthcare-related harm … it is estimated that 27% are preventable and 24% have a
severity of serious (defined as causing “harm … Decision Support Systems
(CDSSs)” [Chapter 6] and summarized eight studies, as well as potential for harm … questions, and will include author,
year, study design, frequency and severity of the harms, measures of harm … questions, and will include author, year, study design, frequency and severity of the harms, measures of harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - For the outcomes of cumulative lifetime incidence and
mortality, life expectancy, numbers needed to harm … and
prevent, and harm-to-benefit ratios, we constructed a semi-
Markov state-transition model of a … Instead of estimating a
cost-effectiveness ratio, we estimated harm-to-benefit
ratios, where total … Systematically varying age at first OC use and duration
of use suggested that the harm-to-benefit ratio … The benefit-to-harm ratio for both incident benefits and
harms, and mortality from those outcomes, from
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - section that harms/complications
would be measured, reporting the occurrence of a procedure-related harm … and the ability
to determine the rate of that harm or reporting that no harms or complications occurred … Radiation — A harm of computed tomography that can increase the risk of developing cancer.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
February 04, 2025 - potential effects” if the 95 percent confidence
interval included meaningful (see Table 2) benefit or harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
September 24, 2024 - potential effects” if the 95 percent confidence
interval included meaningful (see Table 2) benefit or harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - TCA_PCT
Table F-2a. Harms of tricyclic antidepressants versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
August 08, 2019 - Treatments for Acute Pain: A Systematic Review
Evidence-based Practice Center Systematic Review Protocol
Project Title: Treatments for Acute Pain: A Systematic Review
I. Background and Objectives for the Systematic Review
Pain is nearly universal, contributing substantially to morbidity, mortality, disab…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
November 01, 2013 - Evidence of physical or economic harm to individuals or the community led to increased
acceptance of … Descriptions of harm included physical harm (e.g., pain, increased risk of future
injury or illness, … economic harm (e.g., loss of community jobs, high
out-of-pocket expenses for health care). … • Evidence of physical harm was the most persuasive factor in accepting boundaries. … • Evidence of economic harm was also a persuasive factor in restricting choice.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - Opioid Treatments for Chronic Pain Research Protocol
Evidence-based Practice Center Systematic Review Protocol
Project Title: Opioid Treatments for Chronic Pain
I. Background and Objectives for the Systematic Review
Chronic pain, often defined as pain lasting longer than 3 to 6 months, or past the time
of …
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effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - improper randomization would increase the risk of bias for measuring both
outcomes of benefit and harm … Methodological shortcomings predicted lower harm
estimates in one of two sets of studies of clinical
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - Maternal and child benefits and harms outcomes included in the review
Benefit or Harm Mother Fetus, … and emotional development; quality of life
Contact with juvenile justice system
8
Benefit or Harm … Mother Fetus, Infant, Child
Harm Outcomes
• Death, including suicide, all-cause mortality, and
cause-specific … valuable for harms such as
mortality and congenital anomalies, because signals for
increased risk of harm
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care
AHRQ EVIDENCE-BASED PRACTICE CENTER PROGRAM
RESEARCH GAPS SUMMARY:
PRIMARY CARE
An EPC publication summarizing evidence gaps identified across recent EPC reviews for select
healthcare topics
Prepared by:
Angela Carr, R.N., M.…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain
Evidence-Based
Practice
Evidence-based Practice
Program
The Agency for Healthcare Research and
Quality (AHRQ), through its Evidence-
based Practice Centers (EPCs), sponsors
the development of evidence reports and
technology assessments …
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
April 09, 2020 - well-being,
psychosocial well-being, sexual well-being, patient satisfaction with aesthetics, and the harm-related … For KQ 3 (types of implant for IBR) we will also include in the SoE tables the harm-
related outcome … Laboratory findings reveal potential harm of breast implants. Tex Med. 1993 Dec;89(12):7.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - Source: www.effectivehealthcare.ahrq.gov
Published online: November 9, 2015
Evidence-‐‑based
Practice
Center
Systematic
Review
Protocol
Project Title: Tonsillectomy for Obstructive Sleep-Disordered Breathing or Recurrent Throat Infection
in Children
Initial publication date if applicable…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
March 01, 2012 - improper randomization would increase the risk of bias for measuring both
outcomes of benefit and harm … The primary study may have established a separate committee to
evaluate association between the harm … Methodological shortcomings predicted lower harm estimates in one of two sets of
studies of clinical … Methodological shortcomings predicted
lower harm estimates in one of two sets of
studies of clinical