-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
October 01, 2010 - In-Hospital, Off-Label
Uses for rFVIIa1 Evidence on Benefits vs. Usual Care Evidence on Harms vs. Usual Care
Spontaneous
intracranial
hemorrhage*
No effect on mortality or functional status. ���
Attenuation of hematoma expansion. ���
Increased risk for arterial thromboembolic
events, particularly at doses >40 …
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs
Future Research Needs Paper
Number 35
Preventive
Pharmacological
Treatments for Migraine
in Adults: Future
Research Needs
Future Research Needs Paper
Number 35
Preventive Pharmacological Treatments for Migraine
in A…
-
effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/1002-nonpharmacologic-treatment-topic-brief.pdf
June 03, 2024 - Topic Brief: Nonpharmacologic Treatment of Mental Health Conditions in Pregnant and Postpartum People
1
Topic Brief: Nonpharmacologic Treatment of Mental
Health Conditions in Pregnant and Postpartum People
Date: 8/3/2022
Nomination Number: 1002
Purpose: This document summarizes the information addre…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-synthesizing-evidence-improve.pdf
July 01, 2020 - AHRQ’s Evidence-based Practice
Center Program
Synthesizing evidence to improve health care practice and delivery
1
EPC Program Methods for Systematic Reviews
What is the Evidence-based Practice Center Program?
The vision for AHRQ’s Evidence-based Practice Center (EPC) Program is that all health care decisions are…
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - 1
Comparative Effectiveness Review
Number 167
Management of Renal Masses
and Localized Renal Cancer
Executive Summary
Background
Renal masses are a biologically
heterogeneous group of tumors
ranging from benign masses to cancers
that can be indolent or aggressive.1,2
The true incidence of renal masses
(in…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - 1
Source: www.effectivehealthcare.ahrq.gov
Published online: July 24, 2013
Evidence-based Practice Center Systematic Review Protocol
Project Title: Imaging Techniques for the Surveillance,
Diagnosis, and Staging of Hepatocellular Carcinoma
I. Background and Objectives for the Systematic Review
H…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - 1
Comparative Effectiveness Review
Number 76
Treatment for Hepatitis C Virus
Infection in Adults
Executive Summary
Background
Hepatitis C virus (HCV) is the most
common chronic bloodborne
pathogen in the United States. HCV
is primarily acquired by large or
repeated percutaneous exposures to
blood, with …
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
July 01, 2013 - Template for Draft Reports
Future Research
Needs
Long-Term Care
for Older Adults:
Future Research Needs Paper
Number 44
Future Research Needs Paper
Number 44
Long-Ter…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
January 01, 2025 - Trauma Informed Care: A Systematic Review
Systematic Review
Trauma Informed Care:
A Systematic Review
Executive Summary
Main Points
Background and Purpose
Exposure to adverse and potentially traumatic experiences is common and has been
associated with negative mental and physical health out…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - Testing
* Diagnostic accuracy
a
Adverse events;
infection or
hemorrhage;
psychological harm
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - decisions when combining dietary supplements with
cardiovascular medications to provide benefits without harm
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - benefits and harms were analyzed, the
nonpharmacologic treatments demonstrated better benefit-
to-harm
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
November 27, 2012 - expensive, and raises ethical concerns because HCV-
infected persons in a no-screening group would suffer harm … conceptual validity (or lack of) for starting, stopping or more than one
screen and the potential harm … Public Reviewer
#1
Results Key question 5, harm of work-up: Most of these studies center on liver … Harm reduction advice in the form of weight loss and avoidance of ETOH and
tobacco are powerful recommendations … Did you
look at the harm of not knowing?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
May 01, 2013 - The report continually
raises the specter of hypothetical harm from
stigmatization but ignores the … Peer Reviewer 3 Results [P 44, line 52] Are more doctor visits really a
“harm”? … Could
we be causing harm if we implement a screening
program? Ambitious scope. … The
discussion of potential harm of screening is
particularly poor. … This would be grave miscalculation
and could do a great deal of harm.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - antidepressants
often produce multiple side effects that many patients find intolerable, and the risk for
harm
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - Excessive alcohol consumption
is also a major factor in injury and violence.22 Acute alcohol-related harm … However, controlled drinking and
harm reduction are often goals of treatment in parts of Europe. 12,29 … other
outcomes to measure the effectiveness of treatment, which can be subsumed under the
concept of harm
-
effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
January 01, 2011 - Methods Guide for
Comparative Effectiveness Reviews
Assessing the Applicability of Studies When
Comparing Medical Interventions
Comparative Effectiveness Reviews are systematic reviews of existing research on the effectiveness,
comparative effectiveness, and harms of different health care interv…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
January 01, 2011 - Methods Guide for
Comparative Effectiveness Reviews
Assessing the Applicability of Studies When
Comparing Medical Interventions
Comparative Effectiveness Reviews are systematic reviews of existing research on the effectiveness,
comparative effectiveness, and harms of different health care interv…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - reported no SAEs and no difference in
AEs between groups. 31
studies may
signal increase
in serious
harm
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-evidence-summary_0.pdf
June 01, 2021 - Comparative Effectiveness Reiew 243_Prehospital Airway Management: A Systematic Review
Comparative Effectiveness Review
Number 243
Prehospital Airway Management:
A Systematic Review
Evidence Summary
Main Points
• Four Key Questions addressed the comparative benefits and harms across …