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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - The wording
“one or more harm” sounds awkward. … Evidence of Maternal Harm: Overview. Bullet
point 1. … Evidence of Maternal Harm: Overview. Bullet
point 2. … Evidence of Maternal Harm: Overview. Bullet
point 3. … Evidence of Maternal Harm: Overview. Bullet
point 4.
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/1-what-are-the-benefits-and-harms-of-rhythm-control-compared-to-rate-control-including-newer-agents-what-are-the-benefits-and-harms-of-strict-vs-more-lenient-rate-control-2-what-are-the-benefits-and-harms-of-different-antico
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - that the
Agency reconsider the presentation of Table 3 by
providing the references for each listed harm … The "harm" of an incident
osteoporotic fracture during a drug holiday is not really
discussed. … drug
discontinuation versus the reference group of drug
continuation, with incident fractures as a harm … adverse event data are required to determine whether an
intervention is associated with a higher (harm … design), Amgen considers that it
provides the most complete evidence to date on the
efficacy and harm
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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - Evidence Summary: Comparative Effectiveness Review No. 236 Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions
Comparative Effectiveness Review
Number 236
Maternal, Fetal, and Child Outcomes of Mental
Health Treatments in Women:…
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effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
October 01, 2021 - Intergrated and Comprehensive Pain Management Programs: Effectiveness and Harms: Evidence Summary
Comparative Effectiveness Review
Number 251
Integrated and Comprehensive Pain
Management Programs: Effectiveness and
Harms
Evidence Summary
Main Points
Background and Purpose
Pain affects millions …
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
May 14, 2025 - "
- Consider adding a 4th potential harm
(when considering MCST versus SOC in
some cases): the … screening to reduce
cancer incidence is not seen in these novel
strategies and could be considered a harm … We do not think of this as a potential harm;
screening tests are based on early detection. … The number of false-positive results is itself
not a harm; it is a reflection of test accuracy,
which … ; we are aware of the
conclusions offered in that paper suggesting
that it is not a significant harm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0651-131114.pdf
June 20, 2013 - Topic 0552 Low Back Pain NSD FINAL SJ
Diagnosis and Treatment of Low Back Pain
Nomination Summary Document
Results of Topic Selection Process & Next Steps
The topic, Dia…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - osteoarthritis is deciding which
medications will provide the greatest symptom relief
with the least harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - about half of the studies (8 of
16), but the studies reported different harms, did not describe the harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-patient-family-engagement.pdf
October 01, 2023 - emerging area with
few studies evaluating the effectiveness of such engagement in reducing patient harm … advocated for patient and family engagement to be a key
strategy for reducing preventable patient harm … "patient safety"[mh] OR "patient safety" [tiab] OR "Patient Harm"[mh] OR "Patient
Harm*"[tiab] OR … "[MeSH Terms] OR "patient
harm*"[Title/Abstract] OR "patient risk*"[Title/Abstract] OR "quality care … ("patient safety" OR "Patient Harm*" OR "patient risk*" OR "quality care" OR
"adverse event*" OR
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effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
September 01, 2020 - Therapies for Clinically Localized Prostate Cancer: Evidence Summary
Comparative Effectiveness Review
Number 230
Therapies for Clinically
Localized Prostate Cancer
Evidence Summary
Main Points
• In men with clinically localized prostate cancer (CLPC) detected clinically rather than
by prostate-speci…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - violating patients’ trust that healthcare providers are responsible for protecting patients from
harm … advocated for patient and family engagement to be a key
strategy for reducing preventable patient harm … • No clear description of
intervention
Outcome Safety
• Adverse events and incidents
of harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - Medical Therapies for Children With Autism Spectrum Disorder—An Update
1
ww
Comparative Effectiveness Review
Number 189
Medical Therapies for Children With Autism
Spectrum Disorder—An Update
Executive Summary
Introduction
Autism spectrum disorder (ASD) is a
neurodevelopmental disorder broadly
defined by impa…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
April 01, 2020 - have retained the high risk-of-bias in these ratings to communicate the
potential for a signal of harm … an adverse event (N=23) but did not report results
by study arm; this estimate of effect draws from harm-related … Not all
harm-related adverse events are SAEs. … increased but not statistically significant
risk, with relatively wide CIs spanning both
benefit and harm … Psychological treatments that cause harm.
Perspect Psychol Sci. 2007 Mar;2(1):53-70.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - the characteristics of pregnant women and fetuses that will
benefit most or have the lowest risk of harm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
January 01, 2008 - Effective Health Care
Topic Number(s): 0087/0112
Document Completion Date: 6-26-09
1
Results of Topic Selection Process & Next Steps
Typical vs atypical antipsychotics will go forward for refinement as a comparative effectiveness or
effectiveness review. The scope of this topic, including p…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - team’s assessments of whether a proposed
practice meets the definition of a PSP, the likelihood to harm … What deprescribing interventions have been used to prevent or mitigate the
harm and in what settings … What is the rationale for deprescribing to prevent or mitigate the harm?
5. … What Deprescribing Interventions
Have Been Used To Prevent or Mitigate the Harm and in
What Settings … What Is the Rationale for
Deprescribing To Prevent or Mitigate the Harm?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - direction of effect
We recognize that certain outcomes in
this report could be either a benefit or
harm … and report data regardless if the
result was suggesting a benefit or harm. … While the authors
state that the studies were not designed or powered to detect
harm, further statements … readily meaningful to present findings
in the form that “medication A was associated with more of
harm … In the case of
these findings, that might mean estimating the Number Needed
to Harm (NNH), analogously
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
September 15, 2014 - Disposition of Comments for Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments
Comparative Effectiveness Review Disposition of Comments Report
Research Review Title: Chronic Urinary Retention: Comparative Effectiveness
and Harms of Treatments
Draft review available for public…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management
AHRQ EVIDENCE-BASED PRACTICE CENTER (EPC)
PROGRAM RESEARCH GAPS SUMMARY:
PAIN MANAGEMENT
An AHRQ EPC publication summarizing evidence gaps identified across recent EPC reviews
for select healthcare topics addressing the …