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effectivehealthcare.ahrq.gov/health-topics/self-harm
June 02, 2020 - Management of Primary Headaches in Pregnancy
Systematic Review
Draft
June 2, 2020
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effectivehealthcare.ahrq.gov/products/methods-balancing-harms-benefits/research-2012
November 19, 2012 - Methods for Benefit and Harm Assessment in Systematic Reviews
Research Report November 19, 2012 Web … interventions so that decisionmakers with varying preferences can better assess the balance of benefit and harm … Simpler approaches, such as the ratio of the number needed to treat to the number needed to harm, may … be suitable for relatively simple decisionmaking contexts where relevant benefit and harm outcomes are … A framework for organizing and selecting quantitative approaches for benefit-harm assessment.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - >1 outcomes for either benefit
and harm
Benefit and harm
comparison metric
No benefit and harm … balance is uncertain
- Includes only benefit or harm outcomes
- Benefit >> Harm or Harm >> Benefit … harm) in a 3x3 table. … the harm outcome. … benefit and harm and allows for the use of a benefit and harm comparison metric.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - Protocol for Quantitative Assessment of Benefit and Harm analysis of Aspirin for primary prevention … harm
outcomes, such as by putting benefit and harm on the same scale (e.g., quality-adjusted life-years … We identified benefit and harm
outcomes from an updated
systematic review. … and harm assessment for individual subjects. … Methods
for Benefit and Harm Assessment in Systematic
Reviews. Reviews.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-protocol.pdf
January 01, 2024 - Programs for responding after patients experience harm in the course of their health care
were identified … details.1
Overview of the Topic
How healthcare organizations respond after patients experience harm … .14 While healthcare organizations are required by regulatory and accrediting
agencies to analyze harm … ‘implement and maintain programs for providing appropriate ongoing support in
the aftermath of harm … " physical harm
defined as harm whose management is anticipated to
require an invasive medical procedure
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effectivehealthcare.ahrq.gov/products/methods-balancing-harms-benefits
November 19, 2012 - Methods for Benefit and Harm Assessment in Systematic Reviews
Timeline
March 03, 2011 … November 19, 2012
Research Report
Methods for Benefit and Harm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews … of that harm occurring compared to expected benefits would impact recommendations about the use of the … An individual harm would be something like a heart attack, diarrhea, or a seizure. … An individual harm could be excluded because the harms are well-established and do not require another … It can also happen that stakeholders need a review of an intervention’s impact on a specific harm so
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effectivehealthcare.ahrq.gov/products/methods-balancing-harms-benefits/research
February 13, 2014 - Methods
We compared the number-needed-to-treat (NNT) and number-needed-to-harm (NNH) approach and the … When we used relative weights, the Gail/NCI approach showed that aspirin caused more benefit than harm … When we weighted outcomes equally in a sensitivity analysis, the harm from aspirin was greater compared … a single outcome, we found comparable results for the number of people who would have a benefit or harm … A framework for organizing and selecting quantitative approaches for benefit-harm assessment.
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effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - We conclude that consistently depicting benefit
and harm information in frequencies can substantially … In this context, the issue of weighing marginal
benefit and marginal harm depends on and is potentially … Only numeric information
on this harm was presented. … Using the Peto method to
calculate the odds ratio yields an estimate for harm of 7.8
(P � 0.01). … The chance of stroke harm can also be put in similar terms.
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effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
January 01, 2005 - What do we know about how evidence of harm and benefit is communicated in other countries? … What do we know about how evidence of harm and benefit is communicated in other countries? … Does product discuss harm and benefit of treatment with the drug? … service—different context
UK has very explicit link between evidence review and consumer products
Detailed harm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - harms assessed as “individual” or “composite
harms;” composite harms included measures such as any harm … severity of harms is often poorly or
inconsistently defined, which makes determination of whether a harm … of that harm occurring compared to expected benefits
would impact recommendations about the use of … hearing loss, ultrasound for musculoskeletal conditions);
or the review is focused on a particular harm … • When designing a question, you may need different searches for each harm.
8.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-258-diagnostic-errors-summary.pdf
December 01, 2022 - Although overall error and harm rates are derived from three
smaller studies conducted outside the United … Stroke, the
top serious harm-producing disease, is missed an estimated 17% of the time. … Nevertheless, overall diagnostic error and misdiagnosis-related
harm rates are consistent with what has … Overall (i.e., not disease-specific) error and harm rates for Key Question 2 relied
heavily on three … Preventable harm rate estimates derived from two studies conducted at academic centers
(1 in Canada,
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effectivehealthcare.ahrq.gov/products/stem-cell-children/research
February 01, 2012 - SOA, magnitude of effect) was applied to the body of evidence when there was an apparent benefit or harm … SOA was deemed not applicable for diseases where there was no clear evidence of benefit or harm with … history (low strength)
Gaucher Type III compared to ERT (moderate strength)
Evidence suggesting harm … compared to conventional therapy (both low strength)
Conclusions
Evidence demonstrating benefit or harm
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effectivehealthcare.ahrq.gov/products/methods-prioritization-harms/methods
February 02, 2018 - Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews
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effectivehealthcare.ahrq.gov/products/health-outcomes-competing-risks/abstract
February 11, 2010 - Absolute risk reduction for individuals was estimated for both benefit and harm outcomes and presented … evidence applied to most of the registry according to overlapping distributions of estimated benefit and harm … participants were estimated to have strong net harmful treatment effect, that is, the individual estimate of harm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
January 01, 2010 - drug and/or device and/or procedure (must have comparator)
Outcome(s): Benefit(s) of intervention, harm … antiplatelet regimens, LAA occlusive
devices (must have comparator)
Outcome(s): Benefit(s) of intervention, harm … different ACEIs, ARBs, and/or statins (must have comparator)
Outcome(s): Benefit(s) of intervention, harm
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - Executive Summary: Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms
Comparative Effectiveness Review
Number 265
Radiation Therapy for Metastatic Bone
Disease: Effectiveness and Harms
Executive Summary
Main Points
Background and Purpose
Bone metastases are common in advan…
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effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_hickam.ppt
December 01, 2006 - Innovative Methods of Communicating Harms and Benefits of Drug Treatment
Isaac Lipkus, PhD
Communicating Harm
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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - The wording
“one or more harm” sounds awkward. … Evidence of Maternal Harm: Overview. Bullet
point 1. … Evidence of Maternal Harm: Overview. Bullet
point 2. … Evidence of Maternal Harm: Overview. Bullet
point 3. … Evidence of Maternal Harm: Overview. Bullet
point 4.
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effectivehealthcare.ahrq.gov/decision-aids/lung-cancer-screening/static/lung-cancer-screening-patient-encounter.pdf
March 01, 2016 - HARM: False alarms and unneeded
additional testing
A false alarm happens when a person has a
positive … HARM: Radiation Exposure
This includes radiation from screening plus
radiation from additional testing … HARM: Overdiagnosis
Screening may find lung cancer that would not
have harmed the person in his or