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1. Registries for Evaluating Patient Outcomes: A User's Guide: 4th Edition | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/registries-guide-4th-edition/users-guide

2. Methods Guide Atkins (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
   January 01, 2011 - Methods Guide for Comparative Effectiveness Reviews Assessing the Applicability of Studies … This Guide presents issues key to the development of Comparative Effectiveness Reviews and describes … The Methods Guide for Comparative Effectiveness Reviews is a living document, and will be updated as … Comments and suggestions on the Methods Guide for Effectiveness and Comparative Effectiveness Reviews … Methods Guide for Comparative Effectiveness Reviews. AHRQ Publication No. 11-EHC019-EF.

3. Registries for Evaluating Patient Outcomes: A User’s Guide, First Edition | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/registries-guide/research

4. Registries for Evaluating Patient Outcomes: A User's Guide | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/registries-guide

5. Introduction-User-Guide-To-Ocer 130129 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/introduction-user-guide-to-ocer_130129.pdf
   April 26, 2012 - Introduction to Developing a Protocol for Observational Comparative Effectiveness Research: A User’s Guide … It is hoped that researchers and stakeholders will find the User’s Guide useful. … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Registries for Evaluating Patient Outcomes: A User’s Guide. 2nd ed. … Developing an Observational CER Protocol; A User’s Guide

6. Methods Guide for Medical Test Reviews (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
   July 01, 2012 - Methods Guide for Medical Test Reviews 5-1 Chapter 5 Assessing Risk of Bias as a Domain of Quality … In this chapter of the Methods Guide for Medical Test Reviews, we focus on the evaluation of risk of … This chapter complements the original Methods Guide for Effectiveness and Comparative Effectiveness … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Chapter 5 of Methods Guide for Medical Test Reviews (AHRQ Publication No. 12-EHC017).

7. Methods Guide for Medical Test Reviews (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
   July 01, 2012 - Methods Guide for Medical Test Reviews 8-1 Chapter 8 Meta-Analysis of Test Performance When … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EC017. … Using the principles of randomized controlled trial design to guide test evaluation. … Chapter 5 of Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017. … Chapter 8 of Methods Guide for Medical Test Reviews (AHRQ Publication No. 12-EHC017).

8. Training Modules for the Systematic Reviews Methods Guide | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/cer-methods-guide/presentations

9. Ch 1-User-Guide-To-Ocer 130129 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
   August 13, 2012 - While stakeholders may be defined in multiple ways, for the purposes of this User’s Guide, a broad … • What conceptual model will guide the study design and interpretation? … These include a brief guide for stakeholders that highlights opportunities for taking part in AHRQ’ … Subsequent chapters in this User’s Guide provide specific principles for operationalizing the study … Methods Guide for Effectiveness and Comparative Effectiveness Reviews.

10. Methods Guide for Medical Test Reviews - Editorial (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
    July 01, 2012 - Methods Guide for Medical Test Reviews - Editorial E-1 Editorial Methods Guide for Authors of … The editors of the AHRQ General Methods Guide realized, however, that systematic reviews of medical … or that illustrated how to apply the General Methods Guide to medical test evaluation. … Methods Guide for Effectiveness and Comparative Effectiveness Reviews. … Editorial printed in Methods Guide for Medical Test Reviews (AHRQ Publication No. 12-EHC017).

11. Registries for Evaluating Patient Outcomes: A User's Guide, 3rd Edition | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/registries-guide-3rd-edition/overview

12. Methods Guide for Effectiveness and Comparative Effectiveness Reviews | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/cer-methods-guide

13. Ch 4-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
    January 01, 2010 - physiological or psychological basis for the mechanism of action, whether known or hypothesized, should guide … the appropriate comparison group for one- 46 Developing an Observational CER Protocol: A User’s Guide … the Exposure/Outcome Relationship The known properties of the intervention of interest also should guide … The biological mechanism of action, whether known or hypothesized, should guide the development of … the operationalization of exposure. 56 Developing an Observational CER Protocol: A User’s Guide

14. Ch 11-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
    January 03, 2012 - about the use of sensitivity analyses. 146 Developing an Observational CER Protocol: A User’s Guide … best to seek out alternative data sources. 148 Developing an Observational CER Protocol: A User’s Guide … the structure of the specific problem. 152 Developing an Observational CER Protocol: A User’s Guide … It is not intended to be a comprehensive guide to implementing sensitivity analyses. … 158 Developing an Observational CER Protocol: A User’s Guide A plan for including some key sensitivity

15. Suppl-1-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
    January 01, 2011 - by sections that focus on each issue. 162 Developing an Observational CER Protocol: A User’s Guide … access (e.g., providing greater geographic 166 Developing an Observational CER Protocol: A User’s Guide … ),X 5M ,X 5U ) T = f(X 4M ,X 4U ) 170 Developing an Observational CER Protocol: A User’s Guide … 5M and using X 4M as an instrument: 172 Developing an Observational CER Protocol: A User’s Guide … A Guide to Econometrics. 4th Edition ed. Cambridge, MA: The MIT Press; 1998. 5. Wennberg JE.

16. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - The 60 Developing an Observational CER Protocol: A User’s Guide selection of comparison group(s … controlled through design or analysis. 62 Developing an Observational CER Protocol: A User’s Guide … However, if 68 Developing an Observational CER Protocol: A User’s Guide the goal is to compare … The overriding consideration that should guide comparator choice is the generation of evidence that … Developing an Observational CER Protocol: A User’s Guide

17. Suppl-2-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/suppl-2-user-guide-to-ocer_130129.pdf
    January 01, 2011 - nonexperimental studies under certain assumptions.7-8 178 Developing an Observational CER Protocol: A User’s Guide … A←C 1 →C 4 →C 5 →Y is an open path, 180 Developing an Observational CER Protocol: A User’s Guide … difference and resulting in selection bias. 182 Developing an Observational CER Protocol: A User’s Guide … Developing an Observational CER Protocol: A User’s Guide

18. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - evaluate and address bias that may arise. 72 Developing an Observational CER Protocol: A User’s Guide … detect change in an individual over time. 74 Developing an Observational CER Protocol: A User’s Guide … o 90 Developing an Observational CER Protocol: A User’s Guide References 1. … Health Measurement Scales: a Practical Guide to their Development and Use. 4th ed. … Developing an Observational CER Protocol: A User’s Guide

19. Ch-7-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
    March 29, 2012 - reader should note that the recommended 94 Developing an Observational CER Protocol: A User’s Guide … health status in their causal models.11, 13 96 Developing an Observational CER Protocol: A User’s Guide … used to evaluate time-varying treatment. 98 Developing an Observational CER Protocol: A User’s Guide … Epidemiol. 2001;12(6):682-9. 106 Developing an Observational CER Protocol: A User’s Guide 14. … Developing an Observational CER Protocol: A User’s Guide

20. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
    September 21, 2012 - primary outcome if the treatments do indeed 130 Developing an Observational CER Protocol: A User’s Guide … when they consider the feasibility of a 132 Developing an Observational CER Protocol: A User’s Guide … Developing an Observational CER Protocol: A User’s Guide