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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
    September 02, 2016 - prior to measurement of events • Prospective or retrospective cohort (single group) studies, where groups … outcome; missing outcome data were balanced in numbers, with similar reasons for missing data across groups … Group SIMILARITY AT BASELINE (**GENERAL**) There is LOW RISK OF BIAS if groups are similar at baseline … There is HIGH RISK OF BIAS if groups had different omega-3 intake/status at baseline that was not accounted … Was there incomplete COMPLIANCE with interventions across groups?
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
    March 29, 2011 - target Phe levels are appropriate for minimizing or avoiding cognitive impairment for different age groups … For observational studies, we will assess three broad characteristics: 1) the selection of the study groups … ; 2) the comparability of the study groups; and 3) either treatment exposure or the outcome of interest … target Phe levels are appropriate for minimizing or avoiding cognitive impairment for different age groups … ; 2) the comparability of the study groups; and 3) either treatment exposure or the outcome of interest
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
    January 01, 2020 - meta-analysis was the difference in change in BMI or body weight between the intervention and control groups … populations at greatest risk for weight gain including by baseline weight (normal/overweight); age groups … provide quantitative information on an approach of interest and weight or adiposity, such as focus groups … including the following: a clear description of the population, setting, approaches, and comparison groups … We will report on subgroups of interest including baseline weight (normal/overweight); age groups; life
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritized-research-agenda.pdf
    October 01, 2021 - Do particular subgroups (pregnant/postpartum women, those with comorbidities, certain age groups, patients … belonging to particular race/ethnicity/socioeconomic groups) who are screened for depression in a primary … Do particular subgroups (pregnant/postpartum women, those with comorbidities, certain age groups, patients … belonging to particular race/ethnicity/socioeconomic groups) with no prior depression diagnosis or
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
    February 15, 2018 - comment that the degree of difference in allergen reduction between the control and intervention groups … On the other hand, if the trial is negative," if there is no difference between the two groups in … Moreover, the degree of difference in allergen reduction between the control and intervention groups … , for a trial that is "positive", if there is no difference in allergen reduction between the two groups … On the other hand, if the trial is "negative," if there is no difference between the two groups in
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
    August 01, 2012 - Dose: 1 RCT found no differences between dose groups in endpoints November 2011 No new studies … Fasting insulin rose in both groups. … Median latency time for detection of a meningioma was the same in both groups. … Among particular groups (e.g., Prader Willi syndrome, Turner Syndrome, renal insufficiency), deaths … In this trial, no significant differences were seen between the higher and the lower dose groups for
  7. effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
    January 01, 2013 - To ensure internal validity, treatment groups compared must have the same underlying risk for outcome … central assumption needed for nonexperimental comparative effectiveness research is that the treatment groups … Cohort studies allow the estimation of actual incidence (risk or rate) in all treatment groups and thus … uniform periods to define these criteria for all subjects; differences in periods between treatment groups
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
    May 26, 2015 - First, access to integrative interventions for certain occupational groups may be limited. … Most interventions have enrolled very specific occupational groups; the results of these studies may … with historical (rather than concurrent) control KQ1: “Pre-post” cohort studies without a control groups … and attrition bias; concepts covered include those about adequacy of randomization, similarity of groups
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
    July 01, 2012 - age and earlier stage in 2004–2005 than in the mid- to late 1990s, and disparity between ethnic groups … Striking differences in incidence have been observed for different ethnic groups and populations. … African-American men have a poorer prognosis than other groups, independent of comorbidity or access … Atlanta: American Cancer Society; 2010. www.cancer. org/acs/groups/content/@epidemiologysurveilance/
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
    March 10, 2010 - Is there any subgroup reporting of risk equivalent groups? … Perhaps the decision should be to study different genetic groups and move away from less clearly defined … Also additional research is needed on all non-Caucasian groups at present. … Also, certain Asian ethnic groups tend to have differences in BMI (Southeast, East, etc.).
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/future-research-prioritization-methods_research.pdf
    January 01, 2013 - it is desirable that the prioritization process be transparent and as consistent as possible among groups … priority population in particular. 3 Was nominated/strongly supported by one or more stakeholder groups … for resolving important dilemmas in health and health care decisions made by one or more stakeholder groups … Was nominated/strongly supported by one or more stakeholder groups.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - • Need to emphasize to groups that are prioritizing that they should include harms. … • No limit imposed • Groups do bring common / high burden AE to the table, perhaps this is more … How should input from technical and clinical experts and patients or patient advocacy groups be used … • For patients, it depends on the conditions and the efficacy groups • There could be a panel of … Had to report data from groups of in which at least 85% of the patients were from one of the patient
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
    June 01, 2012 - 3, we included studies reporting the outcomes of systematic data collection efforts (e.g., focus groups … Health care professionals, health care workers, and first responders were among the highest priority groups … Finally, the initiative taken by nontraditional providers or groups added innovation and breadth to … Current consensus guidelines and recommendations from specialty societies and government advisory groups … response to MCEs cannot prospectively enroll subjects in a real event, allocate subjects into treatment groups
  14. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/ahrq_community_forum_webinar_bonoff.pdf
    January 01, 2000 - critical appraisal skills • Ground program in adult learning principles: – Repetition, small study groups
  15. effectivehealthcare.ahrq.gov/sites/default/files/bonoff-text.pdf
    January 01, 2000 - § Repetition, small study groups
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
    November 01, 2010 - That is, number of groups, not number of participants, is the appropriate basis for the degrees of … When participants are used, instead of groups, elevated probability of type I error can occur, some … This specific issue arises when studies randomize entire groups (e.g., a classroom) or use a group … I wonder if the G's could be bolded in terms of "target" groups or color coded to represent similar … ), with no clear difference in treatment intensity or outcome between groups.
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
    September 01, 2011 - significant differences in GERD symptoms, diagnostic test results, or quality of life were observed between groups … No significant differences in medication use, GERD symptoms, or quality of life were found between groups … differences in medication use, GERD symptoms, diagnostic test results, or quality of life were found between groups … • No significant differences in medication use, GERD symptoms, or QoL were found between groups. … differences in medication use, GERD symptoms, diagnostic test results, or QoL were found between groups
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/echocardiography_research.pdf
    May 01, 2014 - The algorithm categorizes beneficiaries into four groups: Full Duals had full Medicare and Medicaid … Among racial and ethnic groups, African Americans, Hispanics, and American Indians/Alaska Natives were … First, among age groups, the use of echocar- diography rose steeply until age 85, when it plateaued. … Variations in use within racial/ethnic groups also exist but appear to be stable over the period 2007 … important insights about the use of echocardiography over time and across geographic and demographic groups
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
    August 01, 2013 - Security Disability Insurance (during periods when they are not institutionalized).14 Some advocacy groups … These groups provided input on the KQs, reviewed the protocol, answered specific questions during the … comparative trials that employed a matching procedure to ensure baseline comparability of treatment groups … For each outcome in the review, an important consideration is the smallest difference between groups … ” result as one in which the data were not informative (the CI was too wide to determine that the groups
  20. effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
    March 29, 2012 - antihypertensive treatment and the clinical outcomes of cardiovascular events.1 The difference in treatment groups … The use of statistical methods to make the two treatment groups similar with respect to measured confounders … Due to the ways in which providers and patients choose treatments, the treatment groups may not have … An “as treated” analysis allows subjects to switch treatment groups on the basis of their use of treatment … the predicted probability is then used as a balancing score or matching variable across treatment groups

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