-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - compile studies with multimodal
approaches such as surgery and chemotherapy that are similar between groups … studies will be assessed on the basis of the following criteria:
– Initial assembly of comparable groups … – Maintenance of comparable groups (includes attrition, crossovers, adherence, and
contamination … at least 80%); reliable and valid measurement
instruments are used and applied equally to the groups … Studies are graded “poor” if any of the following fatal flaws exists: Groups
assembled initially are
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_disposition-comments.pdf
May 24, 2013 - not making nor
are we suggesting that research be done making comparisons
across distinct patient groups … trial in 2002, Llovet did include a TAE arm and
showed no difference in survival between the two
groups … We have also amended the FRN section to reflect the importance
of comparing like patient groups. … Therefore comparison
between the 2 groups is always going to introduce
preferential bias favoring the … following:
Reconfigured the PICOTS to group local hepatic therapies into
the following three comparison groups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - balance the
need for smaller studies of specialized populations (e.g.,
studies in specific ethnic groups … neonatal deaths, or neonatal intensive
care unit (NICU) admissions between the intervention and
control groups … reported a
higher incidence of adverse events in women receiving
interventions than in the control groups … “Other” combined relatively rarer
components, such as groups and quit contracts. … One study enrolled adolescents
only, six studies targeted income-specific groups, and
one study specifically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - a higher dose of a statin, and
then provide a broader perspective using available data
in all risk groups … In trials
of this type, oversampling of populations of interest,
including women, ethnic groups, elderly … • Trials including women and the groups identified
above should report results in a manner amenable … not marketed in the United States and another that
failed to report relevant outcomes by treatment groups … simvastatin monotherapy and 20 mg/day
simvastatin plus 2 g/day niacin extended-release
combination groups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
January 01, 2013 - original report
does not need
updating
Vitamin K
One 6-month efficacy trial in 70 selected
groups … the mean percentage reduction in luminal
diameter was not significantly different
between the two groups … aPTT], platelet aggregation), there were
no significant differences between
combination and control groups … Triglycerides decreased in n-3
supplemented groups. … the mean
percentage reduction in luminal diameter was not significantly
different between the two groups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - cognition, but that the mean
differences in cognitive scores between active treatment and control groups … Good randomization produces
study groups that are likely comparable for known and unknown risk factors … In randomized studies, whether there is bias in allocation of study
participants to treatment groups … Attrition bias can potentially change the collective (group)
characteristics of the relevant groups … Detection Bias
DEFINITION
Systematic differences in outcomes assessment among groups being compared
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - estimates equally distributing patient
characteristics and concomitant treatments among treatment groups … Intervention PT interventions hypothesized to improve response in specific groups of patients. … Considerations RCT Prospective Cohort
Design description
Groups of adults with knee OA randomly … RCTs need to be sufficiently powered to
detect differences between groups as
determined by appropriate … Was nominated/strongly supported by one or more stakeholder groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement-benefits_white-paper.pdf
March 01, 2014 - Potential KIs from each of the above groups were identified by members of our working
group and invited … repeatedly identified as the most critical point for engaging stakeholders in general, and
certain groups … they believe they have been
exposed to potentially harmful
circumstances, products or services;
groups … facilitated discussions
with national and international experts
representing diverse stakeholder
groups … That would
involve some interviews or focus groups well after the final report.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
May 29, 2025 - of$this$
document$for$included$drugsh$additional$antihypertensive$therapy$OK$if$the$same$in$both$
groups … F"3$
http:1.13,$P=0.86
http:and$found$no$difference$between$the$groups$in$CVD$risk$(HR$0.99,$95%$CI … $No$difference$between$the$groups$was$observed$in$CVD$risk$
(HR$0.99,$95%$CI$0.87"1.13,$P=0.86). … $There$were$no$significant$differences$in$
adverse$effects$between$groups,$with$the$exception$of$more … and$adverse$events,$including$hyperkalemia$and$acute$kidney$injury,$were$also$similar$in$
the$two$groups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - The Matilla 2003 paper reported two groups,
an RCT which randomly allocated treatment in 137
patients … activity
limitations, hearing loss, or speech impairment between
surgically treated and no surgery groups … health-related
quality-of-life scores indicated good quality of life and
were similar across the groups … in the generic health-related quality-of-life
scores did not differ significantly among the study groups … If possible, trials should be powered
with planned subgroup analyses in groups at higher versus
lower
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
February 01, 2012 - target Phe levels are appropriate for minimizing or
avoiding cognitive impairment for different age groups … Key Question 1b: Evidence for Optimal Phe Levels
To Minimize Cognitive Impairment for Different
Age Groups … will be conducted in both tightly controlled
and nonadherent populations, and among different age
groups … is moderate
for a large positive effect of BH4 on reducing Phe levels
over the short term in some groups … In addition,
data on effectiveness in various groups of patients outside
the clinical trial setting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - Statistically significant difference
between groups for quality of life (SF-36
PCS) that did not reach … However no differences
between groups for functional ability and
quality of life by 2 years and no … dose
prednisone vs. combination with infliximab:
No differences in serious adverse events
between groups … plus MTX than
in those taking
etanercept
alone
No significant
difference in any
AEs across groups … Statistically significant difference
between groups for quality of life (SF-36 PCS) that did
not reach
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - Statistically significant difference
between groups for quality of life (SF-36
PCS) that did not reach … However no differences
between groups for functional ability and
quality of life by 2 years and no … dose
prednisone vs. combination with infliximab:
No differences in serious adverse events
between groups … plus MTX than
in those taking
etanercept
alone
No significant
difference in any
AEs across groups … Statistically significant difference
between groups for quality of life (SF-36 PCS) that did
not reach
-
effectivehealthcare.ahrq.gov/sites/default/files/leong-presenation.pdf
May 29, 2025 - Pa tient adv oc ac y groups had
hug e reserv oirs of inf orm ation
but no one really knew where … There are fac ilitators topatient
engagement
and those fac ilitators are the advoc ac y groups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - analyzed using all patients with stage II colon cancer or whether GEP was used only
after certain groups … The latter
will include information culled from companies, patient advocacy groups, and other
sources … Published Online: March 13, 2012
• Does the final classification provide discrimination among groups … (In addition, when the GEP predicts risk groups, how were
the cut-points for various groups determined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-app-g-1.xlsx
January 01, 2023 - 1.3 Did baseline differences between intervention groups suggest a problem with the randomization process … If Y, PY, NI to previous question) were these deviations from intended intervention balanced between groups … 4.2 Could measurement or ascertainment of the outcome have differed between intervention groups?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-app-e.xlsx
January 01, 2022 - Yes/No/Unclear Groups Similar at Baseline?
Yes/No/Unclear Patient Masked? … Moderate
Bjorseth, 2016 Yes Yes No No No Unclear Yes No No Yes Yes Moderate
Blader, 2009 Yes Unclear No; groups … Were the Groups Comparable at Baseline on Key Prognostic Factors?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure-surveillance-160412.pdf
May 29, 2025 - The"mean"difference"between"the"two"groups"for"
daytime"diastolic"ambulatory"blood"pressure"was"2.3" … $Intervention$and$
control$groups$also$had$
similar$rates$of$blood$
pressure$control$at$9$
months … $The$single$
quality$A$trial$found$no$
difference$between$groups$at$
18$months$followup`$the$other … $Both$groups$
also$had$similar$rates$of$
participants$in$the$
normal$daytime$
ambulatory$blood$ … $The$
mean$difference$between$
the$two$groups$for$
daytime$diastolic$
ambulatory$blood$
pressure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
October 05, 2012 - Intention to treat analysis” is to analyze
randomised controlled trials that compares patients in the
groups … grouped patients that did not distinguish
clinical populations, and we attempted to group patients into groups … We pooled patients into clinically relevant groups based
on the similarities of the groups. … Subdividing the groups further
would results in several sparsely populated groups. … Interestingly, although the PCT and
control groups in this study were similar with respect to individual
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
January 01, 2009 - conditions,
particularly in low-income and underserved patients (including the uninsured, minority
groups