-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - Based on this assessment, the CER was categorized into one of the three updating
priority groups: high … box warning
from FDA, etc.
2.6 Determining Priority for Updating
Determining the priority groups … One RCT demonstrated that only one patient developed major bleeding in the
edoxaban versus placebo groups … Symptomatic PE
difference from
placebo (%)]
0.0 vs. 0.0 in all groups
Symptomatic DVT[#
of … Symptomatic PE difference from
placebo (%)]
0.0 vs. 0.0 in all groups
Symptomatic DVT[# of pts
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
March 01, 2021 - We did not limit our search to
only these disparity groups; we
conducted our search to be
inclusive … of
adding a term such as “non-profit organizations”
or “fund raising organization” or “advocacy
groups … Guiding Question 1, recommend
discussing the direction of the disparities so that
it is clear what groups … This goes beyond disparities
among population groups, as
care is inadequate for
everyone. … We have added
some language to clarify the
ideal comparator groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
September 15, 2014 - We
have revisited the groupings and now divide studies into two
groups based upon underlying etiology … However, the study was only
powered to detect fairly large differences between groups. … However, even then, we identified few studies with comparison
groups. … We have revisited the groupings and now divide studies into two
groups based on underlying etiology … We did not include case series data in our review because case
series data have no comparison groups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - establishing proof of concept for
new testing techniques (such as fecal
calprotectin)
Comparator groups … Comparator groups Standard antibiotic treatments: active treatments
such as metronidazole or vancomycin … One can use case series, but they have
no controls and the rate of “adverse events” among placebo groups … Yes Valid measures, groups ~equivalent
No Non-validated measures or
nonequivalent groups
Uncertain … Were there
attempts to balance
the allocation across
groups?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-3-acute-pain.xlsx
May 29, 2025 - Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-2-acute-pain.xlsx
May 29, 2025 - Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked?
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/telehealth-during-COVID-19-amendments.pdf
April 28, 2022 - Study Design† KQ1: claims and EHR data
KQ 2 and 4
o Qualitative studies: focus groups, interviews … Quantitative studies: RCT, CT, observational
studies, and surveys
KQ3: Qualitative studies: focus groups … observational studies, surveys
Qualitative evidence
synthesis: Qualitative research
(e.g., focus groups … 2022
PICOTS: Study
design
KQ1: claims and EHR data
KQ 2 and 4
o Qualitative studies: focus
groups … KQ3: Qualitative studies‡ (e.g., focus
groups, interviews), surveys
KQ4: Mixed methods (qualitative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - As defined by physician and consumer groups, the core principles
of the PCMH are: wide-ranging team-based … seeking ongoing longitudinal studies,
including pilot and demonstration projects, with comparison groups … validated search
filters (such as the Clinical Queries Filters in PubMed), and will draw on other groups … Country and lending groups. … Available at:
http://data.worldbank.org/about/country-classifications/country-and- lending-groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - • Efficacy of citrate treatment on recurrent stone
outcomes did not differ between patient groups … RCTs averaged
9.5 percent (range 0 to 10) and appeared similar
between intervention and control groups … All treatment groups were
assigned increased fluid intake, so trials evaluated
whether addition of … Magnesium
• In a single eligible RCT, withdrawals were similar in
the magnesium and placebo groups … Instead, nearly all pharmacological trials
reported that all groups were assigned a common
dietary
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
January 01, 2014 - degree.4-23 These reviews have largely
included uncontrolled studies or studies that used control
groups … The direction and magnitude of effect are derived from the
relative difference between groups in the … Sixth, studies found an improvement in outcomes among
the mindfulness groups (compared with control) … There were no
statistically significant differences between groups on
the Attentional Network Test. … Limitations of the Review
Our assessment of a 5-percent relative difference between
groups in change
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/maternal-child-outcomes-wic-disposition-comments.pdf
April 19, 2022 - This paucity of studies is due to the difficulty of identifying comparison
groups of income eligible … Discussion Importance of the review to stakeholders: Expand on reasons why this
review is important to all groups … Policy makers are called out with
more details, rightfully so, but so are other groups (WIC staff, leadership … How will this review be meaningful and accessible to
these groups?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
April 01, 2023 - Evidence Gaps
Study Population
• Use of contemporary comparison groups and
multiple sites to separate … due to
socioeconomic factors, rural location, or geographic
isolation; and from other underserved groups … Study Design
• Randomized controlled trials, with clearly defined
comparison groups and health outcomes … • Studies that include contemporary comparison
groups so the effect of the telehealth consultations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - The single quality
A trial found no difference between groups at 18 months
followup; the other three … Results were
mixed, with five studies finding no difference between
groups, one study finding fewer … The only quality A
trial found no difference between groups at 18 months
followup; the other three … The only quality A trial found no
difference between groups at 18 months followup; the other 3 trials … One quality C trial found no
difference in adverse drug reactions across four groups with different
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
April 01, 2013 - (defined by age, ethnic and racial
groups, and sex),
• psychiatric comorbidities, or
• personal … Our subgroups of interest included
demographic groups (defined by age, sex, and ethnic or
racial groups … We included questions about
adequacy of randomization, allocation concealment,
similarity of groups … For
binary outcomes (e.g., incidence of PTSD), we calculated
the relative risk (RR) between groups. … All the following
subgroups could be considered: (1) demographic groups:
sex, race, or ethnicity; (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - There was no difference in total number
of deaths between the bicalutamide and placebo
groups for men … When
the higher risk subjects were further divided into
intermediate risk and high-risk groups, the benefit … • Distant metastases: No significant difference in distant failure
events between groups at the median … WW) years, there was no difference in total number of deaths between
the bicalutamide and placebo groups … there may be differences in the incidence and
morbidity of prostate cancer across racial or ethnic groups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - Limitations include the lack of
control groups in most studies, exclusion of evidence prior to 1999 … Epilepsy presents a different challenge at different age groups,
particularly among infants with different
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-e.xlsx
January 01, 2023 - Yes/No/Unclear Groups similar at baseline?
Yes/No/Unclear Patient masked? … Were the groups comparable at baseline on key prognostic factors? Did the article report attrition?
-
effectivehealthcare.ahrq.gov/sites/default/files/roblin.pdf
January 01, 2010 - patient, community (friends, family), providers
o Integration and coordination can be within or between groups … discussions by nurse, nutritionist
• Diabetes Social Support randomized controlled trial
o Three study groups … (1 control + 2 intervention)
o Intervention study groups with and without
peer supporters
Slide
-
effectivehealthcare.ahrq.gov/sites/default/files/module_ii1.ppt
June 01, 2011 - an EHC Program stakeholder (O’Haire, 2011)
*
Types of Stakeholders
Stakeholders are people or groups … partners with representatives from local service providers, the city health organization, advocacy groups … partners with representatives from local service providers, the city health organization, advocacy groups … ongoing relationships between research institutions and stakeholders—particularly patients and patient groups … for participation using a variety of venues and approaches, including:
Centralized patient advocacy groups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - Were patients randomly assigned to the study’s groups?
2. … at the time they were assigned to groups? … groups? … Were the two groups treated concurrently?
12. … Was compliance with treatment ≥85% in both of the study’s groups?
13.