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effectivehealthcare.ahrq.gov/sites/default/files/delilberative-methods-design-goold.pdf
May 29, 2025 - Slide 11
Alternatives to Random Sampling
Substantive representation
o Based on extent to which groups … )
Deliberators chosen by socially rooted groups can add value to deliberative
procedures
o Defined … constituency to whom they are accountable
o Groups’ organizing capabilities can increase the power … deliberation (anecdotal evidence)
o Want different points of view about issue – what experiences, groups
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effectivehealthcare.ahrq.gov/sites/default/files/cf_deliberativemethodswebinar_recruiting.pdf
May 29, 2025 - 1
Alternatives to Random Sampling
• Substantive representation
– Based on extent to which groups … )
• Deliberators chosen by socially rooted
groups can add value to deliberative
procedures
– Defined … constituency to whom they are
accountable
– Groups’ organizing capabilities can increase
the power … deliberation (anecdotal evidence)
– Want different points of view about issue –
what experiences, groups
-
effectivehealthcare.ahrq.gov/sites/default/files/hawley-presentation.pdf
May 29, 2025 - white patients are significantly less likely than African-Americans or
other racial ethnic groups … of white patients who agree with
these statements is significantly lower than for the other groups … So you can
see that the white patients in both groups were most strongly satisfied or were … This figure shows that there is a lot of
variation across racial and ethnic groups. … Myers is
showing navigation tailoring works differently in different racial and ethnic groups.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-prepub-final-research-table-rct.xlsx
May 29, 2025 - Yes/No/Unclear Are groups similar at baseline? … demographic, clinical factors that may impact outcomes ≤5 year difference in age; ≤10% difference between groups … For yes: ≤10% between groups or authors report difference is not statistically significant. … Yes/No/Unclear Were the groups comparable at baseline on key prognostic factors? … outcomes and methods to determine outcomes Rate high if:
'No' or 'unclear' for recruitment, comparable groups
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effectivehealthcare.ahrq.gov/sites/default/files/delilberative-methods-design-abelson.pdf
May 29, 2025 - Size of group
o deliberative events can include large groups of 100 – 1000+ or smaller
groups of … meaningful deliberation
Establish clear goals and carefully manage transitions between small and large
groups
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effectivehealthcare.ahrq.gov/sites/default/files/cf_deliberativemethodswebinar_desigingdeliberativeforum.pdf
May 29, 2025 - Size of group
- deliberative events can include large groups of
100 – 1000+ or smaller groups of … deliberation
• Establish clear goals and carefully manage
transitions between small and large groups
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-e.xlsx
July 09, 2025 - RCTs
Author, Year KQ Adequate randomization Concealed allocation Similar baseline groups ITT No post-randomization … exclusions Loss to F/U Loss to F/U or Missing Data Similar for Group Comparable groups maintained Described … NRSIs
Author, Year KQ Selection Unbiased Similar Pre Intervention Groups Loss to F/U Loss to F/U or … Missing Data Similar for Group Comparable Groups Maintained Described Interventions/Exposures and Comparators
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-equity-protocol.pdf
January 01, 2020 - recommended rates.4
Access and utilization of preventive health care differs across racial and ethnic groups … or barrier that might give rise to a disparity resulting in
less preventive care for disadvantaged groups … /
6 exp Population Groups/
7 vulnerable populations/ or working poor/
8 exp Disabled … /
6 exp Population Groups/
7 vulnerable populations/ or working poor/
8 exp Disabled … /
6 exp Population Groups/
7 vulnerable populations/ or working poor/
8 exp Disabled
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Randomization Adequate Allocation Concealment Adequate Patients and Personnel Masked Outcome Assessors Masked Groups … Similar at Baseline Intent-to-Treat Analysis (at Least 95% Analyzed) Attrition <20%; Difference Between Groups
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
January 01, 2021 - Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? … Were the Groups Comparable at Baseline on Key Prognostic Factors (e.g., by Restriction or Matching)? … Were the Groups Comparable at Baseline on Key Prognostic Factors?
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effectivehealthcare.ahrq.gov/sites/default/files/module_i1.ppt
May 29, 2025 - The theory of knowledge exchange posits that investigators and decision-makers are normally separate groups … /organizations
Presenting information or findings at meetings of stakeholder groups/organizations … /organizations
Presenting information or findings at meetings of stakeholder groups/organizations
Involving … Posting a draft document for review & comment
Knowledge Transfer
Attending meetings of stakeholder groups … of stakeholder engagement:
Presenting information of research findings at meetings of stakeholder groups
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
January 01, 2021 - Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? … Were the Groups Comparable at Baseline on Key Prognostic Factors (e.g., by Restriction or Matching)? … Were the Groups Comparable at Baseline on Key Prognostic Factors?
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effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - Defining time 0 for all comparator groups in describing planned analyses is also important. … There is potential for bias associated with different comparison groups (e.g., no intervention, usual … care, historical controls, and comparison groups from other data sources). … One issue with no-treatment comparison groups is how to identify time 0. … and comparison groups come from different databases.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - The degree of
improvement in both function and pain
was similar between groups.
»» The percentage … of patients with an
improvement in RMDQ score of ≥50
percent at 6 weeks was similar in both
groups … with an
improvement in leg pain score of ≥50
percent at 6 weeks was identical in both
treatment groups … Post-hoc adjustment for pain duration
revealed similar pain improvement in both treatment groups
but … which was statistically but not clinically significant
(1.2-point difference in RMDQ score between groups
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
January 01, 2021 - Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? … Were the Groups Comparable at Baseline on Key Prognostic Factors (e.g., by Restriction or Matching)? … Were the Groups Comparable at Baseline on Key Prognostic Factors?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
July 01, 2012 - new biomarker as a prognostic test that can more
accurately place patients into different prognostic groups … The outcome probabilities or
level of risk and other characteristics of prognostic groups are the most … determine how a prognostic test affects the classification of patients into different
prognostic groups … , that is, groups that would be treated differently in
practice because of their predicted outcome. … More relevant are the
estimates of absolute risk in different groups defined by the prognostic test.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Randomization Adequate Allocation Concealment Adequate Patients and Personnel Masked Outcome Assessors Masked Groups … Similar at Baseline Intent-to-Treat Analysis (at Least 95% Analyzed) Attrition <20%; Difference Between Groups
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effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Comparison groups should reflect clinically meaningful choices in real world practice
and be chosen … ,
especially when the comparison groups come
from different treatment modalities (e.g., drug vs. … Comparison Groups From Different Data Sources
Situations may arise when the desired comparison
groups … are not available within the same data
sources as the exposure groups. … and comparison groups come from
different databases.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
November 01, 2013 - We held 24 BCD groups, 6 at each location. … We held 24 CD groups, 6 at each location. … Three facilitators and a note-taker supported these
groups. … We held 4 CP groups, 1 at each
location. … groups.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_consumer.pdf
February 01, 2016 - Note: Medicines are usually used with talk therapy (also called “psychotherapy”) and
support groups … Medicines are usually used with talk therapy and support groups
to treat alcohol use disorder. … � Other support groups: There are many support groups to help
people stop drinking (for example, … Medicines are usually used together with talk therapy and
support groups. … � What support groups can I go to for help?
9
AHRQ Pub.