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1. Final Research Plan: Peripheral Artery Disease and Cardiovascular Disease: Screening and Risk Assessment With the Ankle-Brachial Index | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/peripheral-artery-disease-in-adults-screening-with-the-ankle-brachial-index
   June 16, 2016 - Does the effectiveness of screening for PAD vary by subpopulations at greater risk for PAD? … Do the harms of screening for PAD vary by subpopulations at greater risk for PAD? … Does the effectiveness of treatment vary by subpopulations at greater risk for PAD? … Do the harms of treatment vary by subpopulations at greater risk for PAD? … What proportion of generally asymptomatic adults * with an ABI  greater than 1.40 have PAD?

2. Archived: Published Comment and Response: Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes?: Diabetes Mellitus (Type 2) in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/published-comment-and-response-do-lipid-lowering-agents-provide-a-greater-reduction-in-cardiovascular-events-among-patients-with-diabetes/diabetes-mellitus-type-2-in-adults-screening
   November 15, 2008 - archived Published Comment and Response: Do Lipid-Lowering Agents Provide a Greater Reduction … mellitus than in those without, one would expect that patients with diabetes would benefit more by having greater … evidence on lipid-lowering agents, the USPSTF found that persons with diabetes do not seem to benefit to a greater

3. Archived: Published Comment and Response: Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes?: Diabetes Mellitus (Type 2) in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/published-comment-and-response-do-lipid-lowering-agents-provide-a-greater-reduction-in-cardiovascular-events-among-patients-with-diabetes/diabetes-mellitus-type-2-in-adults-screening-2008
   November 15, 2008 - Print archived Published Comment and Response: Do Lipid-Lowering Agents Provide a Greater … mellitus than in those without, one would expect that patients with diabetes would benefit more by having greater … evidence on lipid-lowering agents, the USPSTF found that persons with diabetes do not seem to benefit to a greater

4. Draft Recommendation: Anxiety in Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/anxiety-adults-screening
   September 20, 2022 - At a cutoff of 3 or greater, the pooled sensitivity was 0.81 (95% CI, 0.73 to 0.89; I 2 =28.8%) and … , 9 or greater, and 10 or greater. 1 At a cutoff of 10 or greater, the pooled sensitivity to detect … At a cutoff of 3 or greater, the sensitivity to detect generalized anxiety disorder was 0.69 (95% CI, … A small study of older adults (N=110) evaluated the GAS using a cutoff of greater than 9 to greater than … Sensitivity to detect any anxiety disorder at a cutoff of greater than 9 was 0.60 (95% CI, 0.31 to 0.83

5. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/6dqHx6xQGq9GUv92rZUf2q
   August 01, 2022 - diabetes, hypertension, or smoking) and an estimated 10-year cardiovascular disease (CVD) risk of 10% or greater … They do not apply to adults with a low-density lipoprotein cholesterol level greater than 190 mg/dL ( … - In patients who have a cardiovascular risk factor and an estimated 10-year CVD risk of 10% or greater

6. Aspirin Use to Prevent Cardiovascular Disease (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/bC4oNwsek4uY3SJZf4S7zm
   April 01, 2022 - C Grade For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease … The USPSTF currently recommends considering initiating aspirin in persons with an estimated 10% or greater … - In patients whose estimated CVD risk is 10% or greater, use shared decision making, taking into

7. Aspirin Use to Prevent Cardiovascular Disease (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/rts4chTw2sVprMEF5xpMYS
   April 01, 2022 - C Grade For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease … The USPSTF currently recommends considering initiating aspirin in persons with an estimated 10% or greater … - In patients whose estimated CVD risk is 10% or greater, use shared decision making, taking into

8. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
   May 01, 2021 - dyslipidemia, diabetes, hypertension, or smoking) and an estimated 10-year CVD event risk of 10% or greater … The likelihood of benefit is smaller in this group than in persons with a 10-year risk of 10% or greater … The higher a person’s 10-year risk of a CVD event, the greater the chance of benefit from statin use. … For patients with an es- timated 10-year CVD risk of 10% or greater and who smoke or have Adults aged … They do not apply to adults with a low-density lipoprotein cholesterol level greater than 190 mg/dL (

9. Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
   August 23, 2022 - more cardiovascular risk factors and an estimated 10-year cardiovascular disease (CVD) risk of 10% or greater … The likelihood of benefit is smaller in this group than in persons with a 10-year risk of 10% or greater … They do not apply to adults with a low-density lipoprotein cholesterol level greater than 190 mg/dL ( … In patients who have a cardiovascular risk factor and an estimated 10-year CVD risk of 10% or greater … The higher a person’s 10-year risk of a CVD event, the greater the chance of benefit from statin use.

10. Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: USPSTF Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fMLEz4CfAVoj9YBYVbm73
    April 17, 2018 - The USPSTF found inadequate evidence to estimate the benefits of doses greater than 400 IU of vitamin … D or greater than 1000 mg of calcium to prevent fractures in community-dwelling postmenopausal women … than 400 IU of vitamin D and greater than 1000 mg of calcium for the primary prevention of fractures … than 400 IU of vitamin D and greater than 1000 mg of calcium in postmenopausal women. … than 400 IU of vitamin D and greater than 1000 mg of calcium in postmenopausal women.

11. Recommendation: Anxiety Disorders in Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/anxiety-adults-screening
    June 20, 2023 - , 9 or greater, and 10 or greater. 1 , 28 At a cutoff of 10 or greater, the pooled sensitivity to detect … At a cutoff of 3 or greater, the sensitivity to detect generalized anxiety disorder was 0.69 (95% CI, … than 9 to greater than 16. … A cutoff of greater than 9 demonstrated the optimal balance of sensitivity (0.60 [95% CI, 0.31-0.83]) … Adequate evidence to bound the magnitude of harms of psychotherapy as no greater than small, based on

12. Recommendation: Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-to-prevent-cardiovascular-disease-preventive-medication
    April 26, 2022 - Population Recommendation Grade Adults aged 40 to 59 years with a 10% or greater … low-dose aspirin use for the primary prevention of CVD in adults aged 40 to 59 years who have a 10% or greater … For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease (CVD) … The USPSTF currently recommends considering initiating aspirin in persons with an estimated 10% or greater … In patients whose estimated CVD risk is 10% or greater, use shared decision-making, taking into account

13. Recommendation: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication
    April 17, 2018 - is insufficient to assess the balance of the benefits and harms of daily supplementation with doses greater … than 400 IU of vitamin D and greater than 1000 mg of calcium for the primary prevention of fractures … than 400 IU of vitamin D and greater than 1000 mg of calcium for the primary prevention of fractures … than 400 IU of vitamin D and greater than 1000 mg of calcium in postmenopausal women. … than 400 IU of vitamin D and greater than 1000 mg of calcium in postmenopausal women.

14. Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/LPaUxRbrTshfsYVVTzenEQ
    April 26, 2022 - aspirin use for the primary prevention of CVD events in adults aged 40 to 59 years who have a 10% or greater … Adults aged 40 to 59 years with a 10% or greater 10-year cardiovascular disease (CVD) risk The decision … The benefits of initiating aspirin use are greater for individuals at higher risk for CVD events (eg, … For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease (CVD) … aged 40 to 59 years with 10% or greater 10-year CVD risk and that initiation of aspirin use has no net

15. Screening for Anxiety Disorders in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/mx2Ko29RH46mTYb36f-UBe
    June 20, 2023 - • Adequate evidence to bound the magnitude of harms of psychotherapy as no greater than small, based … ) • The USPSTF found that the harms of pharmacotherapy in general adults are no greater than moderate … At a cutoff of 3 or greater, the pooled sensitivity was 0.81 (95% CI, 0.73- 0.89; I2 = 28.8%) and the … , 9 or greater, and 10 or greater.1,28 At a cutoff of 10 or greater, the pooled sensitivity to detect … than 9 to greater than 16.

16. Archived: Adolescent Idiopathic Scoliosis: Screening, 1996 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/adolescent-idiopathic-scoliosis-screening-1996
    January 01, 1996 - A lateral spinal curve of 11 degrees or greater is present in about 2-3% of adolescents at the end of … Curves greater than 20 degrees occur in less than 0.5% of adolescents. 4 The potential adverse effects … There is little firm evidence that persons with idiopathic scoliosis are at significantly greater risk … prevalence for this degree of curvature of 3%. 30 In another study, the PPV was 54% for curves greater … than 10 degrees (prevalence of 2%) and 24% for curves greater than 20 degrees (prevalence of 1%).

17. Draft Recommendation: High Body Mass Index in Children and Adolescents: Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/high-body-mass-index-children-adolescents-interventions
    December 12, 2023 - and adolescents. 1 Effective, high-intensity (≥26 contact hours) behavioral interventions result in greater … Liraglutide was associated with 1.6 kg/m 2 greater reduction in BMI than placebo (mean difference, - … 1.6 kg/m 2 [95% CI, -2.5 to -0.7 kg/m 2 ] after 13 months), semaglutide with a 6.0 kg/m 2 greater reduction … 95% CI not reported]; p=0.001; after 12 months), and phentermine/topiramate with 3.7 to 5.4 kg/m 2 greater … The USPSTF found adequate evidence to bound the harms of pharmacotherapy as no greater than moderate

18. Evidence Summary: Nonpregnant Adolescents and Adults: Human Immunodeficiency Virus (HIV) Infection: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - conducted completely or partially in low-resource settings found ART initiation at CD4 cell counts greater … New evidence extends effectiveness of ART to asymptomatic individuals with CD4 cell counts greater than … A prespecified subgroup analysis was conducted in people with a CD4 cell count of 500/mm 3 or greater … Immediate vs Delayed ART in People With Baseline CD4 Cell Count Greater Than 500/mm 3 Two new RCTs … New data extend evidence on effectiveness of ART to people with CD4 cell counts greater than 500/mm,

19. Draft Recommendation: Lipid Disorders in Children and Adolescents: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/lipid-disorders-children-adolescents-screening
    January 24, 2023 - adults from six U.S. cohorts found that the FH phenotype, defined by an LDL-C level of 190 mg/dL or greater … over 30 years of followup, compared with a reference group defined by an LDL-C level of 130 mg/dL or greater … Pooled analyses demonstrated that statins were associated with an 81 to 82 mg/dL greater mean difference … Abnormal creatine kinase levels 10 times or greater the upper limit of normal ranged from 0% to 4.5% … Results showed that exposure to LDL-C levels of 100 mg/dL or greater in young adulthood was associated

20. Understanding Task Force Recommendations: Screening for Prostate Cancer (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/vE-aXbtxnsR_rzarYYyAEd
    May 01, 2012 - It concluded that the expected harms of PSA screening are greater than the potential benefit. … Older men, African-American men, and men who have a family history of prostate cancer have a greater … Task Force recommends against screening, it is because the potential benefits of screening are not greater … The expected harms are greater than the small potential benefit. 1The Task Force recommends against