-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - Nature and Burden of Bone Metastases
Spine and non-spine bone metastases are common in advanced cancers … on histology) with median
survival of 25, 27, 6 months and 3 to 7 months, respectively, for these cancers … The strength of evidence will be assigned an overall grade of high, moderate, low, or
insufficient according … De Felice F, Piccioli A, Musio D, et al. … Atkins D, Chang S, Gartlehner G, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - Hypoglycemia
Liver injury
Congestive heart failure
Severe lactic acidosis
Cancer
Severe … Adverse events include congestive heart failure,
hypoglycemia, pancreatitis, fractures, and cancer. … D. … Jadad AR, Moore RA, Carroll D, et al. … Adverse events include congestive heart failure,
hypoglycemia, pancreatitis, fractures, and cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
September 01, 2014 - We rated the primary studies using a three-grade system
(A, B, or C), evaluating each type of study … Grade A studies have the least bias, and
their results are considered valid within the limits of
interpretation … Grade B studies are
susceptible to some bias, but the amount is not sufficient to
invalidate the results … Grade C studies have significant bias
that may invalidate the results. … The studies of men or of both sexes, and of specific
cancers, did not have consistent findings of associations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - The RDA changes to 175 g/d during pregnancy and 210 g/d
during breast feeding. … D. … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes
We will grade the strength … of the body of evidence (SOE) per the EPC methods guide on
assessing SOE.34 We will grade SOE for end … carbohydrate quantity and quality and risk of
cardiovascular disease, all-cause, cardiovascular and cancer
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
May 14, 2010 - In addition, for each question, we will apply the criteria of the GRADE Working Group
to assess the … National Cancer Institute. Common Terminology Criteria for Adverse Events (CTCAE).
Version 4.0. … Jadad, A.R.; Moore R.A., Carroll D., et al. … Guyatt GH, Oxman AD, Vist G, et al. for the GRADE Working Group. … Rating quality of
evidence and strength of recommendations GRADE: an emerging consensus on rating
quality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - it might be more
effective than medical therapy for prevention of
Barrett’s esophagus and esophageal cancer … followup was 8
months, and all three studies had significant bias
that may invalidate the results (Grade … These
analyses had minimal bias and their results are
considered valid (Grade A). … (Grade C) nonrandomized study. … part of the following
document: Ip S, Bonis P, Tatsioni A, Raman G, Chew P,
Kupelnick B, Fu L, DeVine D,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
January 01, 2014 - We classified
evidence into four basic categories: (1) “high” grade,
indicating high confidence that … research is very unlikely
to change our confidence in the estimate of the effect;
(2) “moderate” grade … confidence
in the estimate of the effect and is likely to change
the estimate; and (4) “insufficient” grade … Ledesma D, Kumano H. Mindfulness-based stress reduction and
cancer: a meta-analysis. … Breast Cancer Res Treat. 2012 Jan;131(1):99-109.
66. Smith JC.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
April 09, 2020 - Implant deflation*
o Implant malposition*
o Need for explant surgery*
o Capsular contracture*
o New neoplasms … Implant deflation*
o Implant malposition*
o Need for explant surgery*
o Capsular contracture*
o New neoplasms … Relative clinical effects of various flap types for AR
• Harms of various flap types for AR
We will grade … evidence “any estimate of effect is very
uncertain,” the definition of Very Low quality evidence per GRADE … Rupani A, Frame JD, Kamel D.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - comorbidities (e.g., seizure history, stroke, diabetes,
dementia, perinatal, ischemic heart disease, cancer … D. … based on the standard methods of the EPCs, which use a
revised version of the approach devised by the GRADE … working group.4 Developed to grade the
quality of evidence and the strength of recommendations, this … Atkins D, Eccles M, Flottorp S, et al, for the GRADE Working Group.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
June 01, 2012 - HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
June 01, 2012 - HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors. … HER2 testing to manage patients with breast cancer or other solid tumors.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - C-1
Appendix D. … D-1
Appendix E. … GRADE guidelines 6. Rating the quality of
evidence--imprecision. … D-1
Appendix D. Literature Flow Diagram
Figure D-1. … Takakuwa KM, Sulak D.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
July 09, 2024 - cancersb Solid tumor cancers, including breast, prostate, testicular,
cervical, and colon cancer. … D. … / or exp "Neoplasms, Germ Cell and Embryonal"/ or
(hematologic cancer* or hematologic neoplasms or hematologic … Neoplasms/ or liver neoplasms/ or Prostatic Neoplasms/ or Testicular Neoplasms/ or
Testicular Neoplasms … / or Uterine Cervical Neoplasms/ or ((cancer* or carcinoma?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - Executive Summary
Main Points
Background and Purpose
Bone metastases are common in advanced cancers … Effect Size/SOE)a
Any time No evidence No difference
+ No evidence
Harms/AEs – Toxicity, Acute Grade … = stereotactic body radiation therapy; SCC = spinal cord compression; SINS = Spinal
Instability in Neoplasia … Primary tumor type, bone metastasis location, and patient
characteristics also differed across included … AC, Chang E, Bordley J, Brodt ED, Selph S, Fu R, Yu Y, Holmes R, Dana T,
Stabler-Morris S, Riopelle D,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - D. … Thrall G, Lane D, Carroll D, et al. … Owens DK, Lohr KN, Atkins D, et al. … [tiab] OR
cancers[tiab] OR tumor[tiab] OR tumors[tiab] OR tumours[tiab] OR tumour[tiab] OR
carcinoma … [tiab] OR carcinomas[tiab] OR neoplasm[tiab] or neoplasms[tiab] OR HIV[tiab] OR
"human immunodeficiency
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - d. KQ3 (p. 4):
i. … D. … Undertreatment of cancer pain in elderly patients. JAMA 1998;279:1914-
5.
16. Ferrell BA. … Atkins D, Best D, Briss PA, et al. Grading quality of evidence and strength of
recommendations. … Atkins D, Briss PA, Eccles M, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
January 01, 2024 - Dowell D, Haegerich TM, Chou R. … Dowell D, Haegerich TM, Chou R. … Aviram J, Atzmony D, Eisenberg E. … Nguyen T, Li Y, Greene D, et al. … Nguyen T, Li Y, Greene D, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - deaths due to NSAID-induced gastrointestinal complications,8
a higher death rate than that for cervical cancer … NSAIDs) includes studies of these drugs for treating osteoarthritis or rheumatoid
arthritis and for cancer … No pharmaceutical grade formulation is
approved by the FDA. … D. … Owens DK, Lohr KN, Atkins D, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
January 01, 2025 - Neoplasia. 2023 Dec;46:100941. doi: 10.1016/j.neo.2023.100941. PMID: 37918207. … Validation cohort ("V") included 82 participants with GI cancers, 11 participants with benign tumors, … Cancer Research; The Virginia and D. … Staging per TNM Classification of Malignant Tumors by Union for International Cancer Control, 8th ed. … Research; The Virginia and D.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
January 01, 2025 - Neoplasia. 2023 Dec;46:100941. doi: 10.1016/j.neo.2023.100941. PMID: 37918207. … Validation cohort ("V") included 82 participants with GI cancers, 11 participants with benign tumors, … Cancer Research; The Virginia and D. … Staging per TNM Classification of Malignant Tumors by Union for International Cancer Control, 8th ed. … Research; The Virginia and D.