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861. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - The study was penalized in the GRADE tables because of possibly inadequate concealment of allocation … We request that the GRADE score of the study be modified accordingly. … events – combination therapy: 83/110 should be 85/113 (75%) All cause mortality: changes made on GRADE … Table 15 was updated Derosa 2004, and Table 52 GRADE was also updated stating that this study had NO … Here, we provide additional data on five key studies, and request that the GRADE tables be revised accordingly

862. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
     July 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

863. Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
     January 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

864. Disposition of Comments for Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
     January 01, 2012 - The Community Task Force omits C grade studies in their summary statements.

865. Evidence Summary Comparative Effectiveness Review 216 Telehealth for Acute and Chronic Care Consultations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
     April 01, 2019 - Guide for Effectiveness and Comparative Effectiveness Reviews.14 We assigned a strength of evidence grade

866. S158 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
     October 01, 2007 - . ‡1 unit increase in category of education (up to 12th grade, high school, associate degree or more)

867. Disposition of Comments Technical Brief 41: Evaluation of Mental Health Mobile Applications (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
     May 20, 2022 - the strength of the evidence of an intervention would necessitate a systematic review and use of GRADE

868. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - Source: www.effectivehealthcare.ahrq.gov Published Online: December 16, 2011 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Treatments for Restless Legs Syndrome I. Background and Objectives for the Systematic Review Overview Restless legs syndr…

869. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression—An Update to a 2007 Report. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
     December 01, 2011 - Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression—An Update to a 2007 Report. Source: http://www.effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and- reports/?pageaction=displayproduct&productid=727 Published Online: July 2011 …

870. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
     February 01, 2010 - Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials Comparative Effectiveness Review Number 9 Addendum Addendum to: Comparative Effectiveness of Percutane…

871. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - strength of evidence methods must meet accepted AHRQ EPC standards (such as Cochrane review methods or GRADE … replacing de novo review processes that did not provide a strength of evidence assessment based on a GRADE … or GRADE-equivalent method and incorporating all relevant articles, including new articles identified

872. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - very similar to that used in the Grading of Recommendations Assessment, Development and Evaluation (GRADE … As in all SOE systems the final grade incorporates unavoidable subjective interpretation, however, we … effects and insufficient for decisionmaking) to those of an independent systematic review team using the GRADE … the FDA, or guideline-issuing bodies) are expected to use the review of the evidence and the SOE grade … apparent discordance between the some of the existing recommendations for practice and the report’s SOE grade

873. Disposition of Comments Report for Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol Misuse (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_disposition-comments.pdf
     July 10, 2012 - strength of evidence; it is one of several things that contributed to the LOW strength of evidence grade

874. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - methods outlined in the AHRQ “Methods Guide for Effectiveness and Comparative Effectiveness Reviews” to grade … directness, precision, and reporting bias, with the body of evidence assigned a strength-of-evidence grade … In cases in which evidence did not exist, was sparse, or contained irreconcilable inconsistency, a grade … differences include the addition of a large volume of newer evidence, the use of a formal system to grade

875. Glaucoma-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
     April 01, 2012 - grading scheme recommended by the Grading of Recommendation Assessment, Development and Evaluation (GRADE … If an outcome was evaluated by only one or by no RCT, our evidence grade was based on the single RCT

876. Trauma-Child-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
     February 01, 2013 - We used a qualitative process, considering each of the domains, to determine the overall SOE grade for

877. Binge-Eating Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
     December 01, 2015 - A grade of high strength of evidence indicates that we have high confidence that the evidence reflects … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons

878. Coronary-Artery-Stenting Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
     February 01, 2013 - The evidence was derived from studies that focused on men with lower grade angina, and excluded patients … Specifically, the evidence was derived from studies that focused on men with lower grade angina, and … patient-centered outcomes in studies that focused on men with intermediate coronary disease and lower grade … Furthermore, the majority of the eligible studies focused on men with lower grade disease, and excluded

879. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
     January 07, 2016 - think the strength of evidence is (with an explanation of why you gave the evidence that particular grade … effect.6 “ We better describe how risk of bias is used to assess study limitations when using the GRADE … say KDIOG guideline recommends using NAC but it looks like the report “suggests” use and gives it a grade … debate and involvement of stakeholders before policy can be determined” and the level of evidence grade

880. Liver-Cancer Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - 1 Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma Executive Summary Background and Objectives Hepatocellular carcinoma (HCC) is the most common primary malignant neoplasm of the liver, usually developing in individuals with chronic liver disease or cirrhosis. Worldwide, it is the f…