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841. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
     July 01, 2012 - Once systematic reviewers identify and abstract the relevant literature, they may grade the body of

842. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
     July 01, 2024 - risk of bias studies and provided Grading of Recommendations Assessment, Development and Evaluation (GRADE

843. Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
     August 15, 2023 - low-quality evidence per the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE

844. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
     August 17, 2011 - Source: www.effectivehealthcare.ahrq.gov Published Online: August 17, 2011 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Public Reporting as a Quality Improvement Strategy: A systematic review of the multiple pathways public reporting may influence quality of health care …

845. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - pneumonia must receive antibiotics, it is not clear whether a 55-year-old man with a localized low-grade … the case of conditions for which there is not an optimal treatment choice, such as localized low- grade … For example, choosing to remove or destroy a low-grade prostatic malignancy can lead to complications

846. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: April 28, 2011 Page 1 of 26 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular D…

847. Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
     September 16, 2022 - • Reporting bias (suspected or undetected) The strength of evidence will be assigned an overall grade

848. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - High grade (indicating high confidence that the evidence reflects the true effect, and further research … Moderate grade (indicating moderate confidence that the evidence reflects the true effect, and further … Low grade (indicating low confidence that the evidence reflects the true effect, and further research … Insufficient grade (evidence is unavailable). … We also found low-grade evidence to support the idea that UFH reduces the rates of total mortality

849. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - The study was penalized in the GRADE tables because of possibly inadequate concealment of allocation … We request that the GRADE score of the study be modified accordingly. … events – combination therapy: 83/110 should be 85/113 (75%) All cause mortality: changes made on GRADE … Table 15 was updated Derosa 2004, and Table 52 GRADE was also updated stating that this study had NO … Here, we provide additional data on five key studies, and request that the GRADE tables be revised accordingly

850. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
     July 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

851. Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
     January 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

852. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - strength of evidence methods must meet accepted AHRQ EPC standards (such as Cochrane review methods or GRADE … replacing de novo review processes that did not provide a strength of evidence assessment based on a GRADE … or GRADE-equivalent method and incorporating all relevant articles, including new articles identified

853. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - very similar to that used in the Grading of Recommendations Assessment, Development and Evaluation (GRADE … As in all SOE systems the final grade incorporates unavoidable subjective interpretation, however, we … effects and insufficient for decisionmaking) to those of an independent systematic review team using the GRADE … the FDA, or guideline-issuing bodies) are expected to use the review of the evidence and the SOE grade … apparent discordance between the some of the existing recommendations for practice and the report’s SOE grade

854. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - methods outlined in the AHRQ “Methods Guide for Effectiveness and Comparative Effectiveness Reviews” to grade … directness, precision, and reporting bias, with the body of evidence assigned a strength-of-evidence grade … In cases in which evidence did not exist, was sparse, or contained irreconcilable inconsistency, a grade … differences include the addition of a large volume of newer evidence, the use of a formal system to grade

855. Glaucoma-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
     April 01, 2012 - grading scheme recommended by the Grading of Recommendation Assessment, Development and Evaluation (GRADE … If an outcome was evaluated by only one or by no RCT, our evidence grade was based on the single RCT

856. Trauma-Child-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
     February 01, 2013 - We used a qualitative process, considering each of the domains, to determine the overall SOE grade for

857. Binge-Eating Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
     December 01, 2015 - A grade of high strength of evidence indicates that we have high confidence that the evidence reflects … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons

858. Coronary-Artery-Stenting Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
     February 01, 2013 - The evidence was derived from studies that focused on men with lower grade angina, and excluded patients … Specifically, the evidence was derived from studies that focused on men with lower grade angina, and … patient-centered outcomes in studies that focused on men with intermediate coronary disease and lower grade … Furthermore, the majority of the eligible studies focused on men with lower grade disease, and excluded

859. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
     January 07, 2016 - think the strength of evidence is (with an explanation of why you gave the evidence that particular grade … effect.6 “ We better describe how risk of bias is used to assess study limitations when using the GRADE … say KDIOG guideline recommends using NAC but it looks like the report “suggests” use and gives it a grade … debate and involvement of stakeholders before policy can be determined” and the level of evidence grade

860. Liver-Cancer Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - 1 Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma Executive Summary Background and Objectives Hepatocellular carcinoma (HCC) is the most common primary malignant neoplasm of the liver, usually developing in individuals with chronic liver disease or cirrhosis. Worldwide, it is the f…