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841. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
     July 01, 2012 - Once systematic reviewers identify and abstract the relevant literature, they may grade the body of

842. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
     July 01, 2024 - risk of bias studies and provided Grading of Recommendations Assessment, Development and Evaluation (GRADE

843. Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
     August 15, 2023 - low-quality evidence per the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE

844. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
     August 17, 2011 - Source: www.effectivehealthcare.ahrq.gov Published Online: August 17, 2011 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Public Reporting as a Quality Improvement Strategy: A systematic review of the multiple pathways public reporting may influence quality of health care …

845. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - pneumonia must receive antibiotics, it is not clear whether a 55-year-old man with a localized low-grade … the case of conditions for which there is not an optimal treatment choice, such as localized low- grade … For example, choosing to remove or destroy a low-grade prostatic malignancy can lead to complications

846. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: April 28, 2011 Page 1 of 26 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular D…

847. Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
     September 16, 2022 - • Reporting bias (suspected or undetected) The strength of evidence will be assigned an overall grade

848. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - Public Comment #3 (APA) Appendices A-19 Grading line 2 I've not seen the phrase "short GRADE" before … May wish to add "to grade the overall strength of a body of evidence." after Program and start the next … The sample size issues addressed in the last sentence seem like less of a focus of the GRADE and EBPC … It's never been clear to me why AHRQ, GRADE, and RoB determinations don't incorporate those factors

849. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - High grade (indicating high confidence that the evidence reflects the true effect, and further research … Moderate grade (indicating moderate confidence that the evidence reflects the true effect, and further … Low grade (indicating low confidence that the evidence reflects the true effect, and further research … Insufficient grade (evidence is unavailable). … We also found low-grade evidence to support the idea that UFH reduces the rates of total mortality

850. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - The study was penalized in the GRADE tables because of possibly inadequate concealment of allocation … We request that the GRADE score of the study be modified accordingly. … events – combination therapy: 83/110 should be 85/113 (75%) All cause mortality: changes made on GRADE … Table 15 was updated Derosa 2004, and Table 52 GRADE was also updated stating that this study had NO … Here, we provide additional data on five key studies, and request that the GRADE tables be revised accordingly

851. Making Healthcare Safer IV: High Reliability Organization (HRO) as a Patient Safety Practice (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
     January 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

852. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
     July 01, 2023 - If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

853. Mrsa-Screening-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
     January 01, 2010 - The overall SOE grade was determined in compliance with the AHRQ “Methods Guide for Effectiveness and … based on a system developed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE … The grade of evidence strength was classified into the following four categories: high, moderate, low … The grade rating was made by independent reviewers, and disagreements were resolved by consensus adjudication … quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE

854. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - strength of evidence methods must meet accepted AHRQ EPC standards (such as Cochrane review methods or GRADE … replacing de novo review processes that did not provide a strength of evidence assessment based on a GRADE … or GRADE-equivalent method and incorporating all relevant articles, including new articles identified

855. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - very similar to that used in the Grading of Recommendations Assessment, Development and Evaluation (GRADE … As in all SOE systems the final grade incorporates unavoidable subjective interpretation, however, we … effects and insufficient for decisionmaking) to those of an independent systematic review team using the GRADE … the FDA, or guideline-issuing bodies) are expected to use the review of the evidence and the SOE grade … apparent discordance between the some of the existing recommendations for practice and the report’s SOE grade

856. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - methods outlined in the AHRQ “Methods Guide for Effectiveness and Comparative Effectiveness Reviews” to grade … directness, precision, and reporting bias, with the body of evidence assigned a strength-of-evidence grade … In cases in which evidence did not exist, was sparse, or contained irreconcilable inconsistency, a grade … differences include the addition of a large volume of newer evidence, the use of a formal system to grade

857. Glaucoma-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
     April 01, 2012 - grading scheme recommended by the Grading of Recommendation Assessment, Development and Evaluation (GRADE … If an outcome was evaluated by only one or by no RCT, our evidence grade was based on the single RCT

858. Binge-Eating Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
     December 01, 2015 - A grade of high strength of evidence indicates that we have high confidence that the evidence reflects … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons

859. Trauma-Child-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_executive.pdf
     February 01, 2013 - We used a qualitative process, considering each of the domains, to determine the overall SOE grade for

860. Coronary-Artery-Stenting Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
     February 01, 2013 - The evidence was derived from studies that focused on men with lower grade angina, and excluded patients … Specifically, the evidence was derived from studies that focused on men with lower grade angina, and … patient-centered outcomes in studies that focused on men with intermediate coronary disease and lower grade … Furthermore, the majority of the eligible studies focused on men with lower grade disease, and excluded