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421. Disposition of Comments Report for Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma-Cell Dyscrasias (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
     August 23, 2012 - of the articles selected for full screening were rejected, and none of the accepted articles were grade

422. Stem-Cell-Children Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
     February 01, 2012 - The SOA domain provided justification for increasing the overall GRADE (Grading of Recommendations

423. Hepatitis-C-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
     November 01, 2012 - for each comparison and outcome using the four categories recommended in the AHRQ guide.59 A “high” grade … A “moderate” grade indicates moderate confidence that the evidence reflects the true effect and further … A “low” grade indicates low confidence that the evidence reflects the true effect and further research … An “insufficient” grade indicates evidence either is unavailable or too limited to permit a conclusion

424. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
     May 01, 2022 - the strength of evidence is reviewed by the entire team of investigators prior to assigning a final grade … Reporting/publication bias (suspected or undetected) The strength of evidence was assigned an overall grade … GRADE guidelines 6. Rating the quality of evidence--imprecision. … Consistency Precision Publication Bias Main Findings Effect Size (95% CI) Strength of Evidence Grade … Trial Assessing the Tolerability of Two Different Ratios of Medicinal Cannabis in Patients With High Grade

425. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
     March 01, 2022 - the strength of evidence is reviewed by the entire team of investigators prior to assigning a final grade … Reporting/publication bias (suspected or undetected) The strength of evidence was assigned an overall grade … GRADE guidelines 6. Rating the quality of evidence--imprecision. … Consistency Precision Publication Bias Main Findings Effect Size (95% CI) Strength of Evidence Grade … Trial Assessing the Tolerability of Two Different Ratios of Medicinal Cannabis in Patients With High Grade

426. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … The aim will be to identify and grade those outcomes that are critical for decisionmaking. … We will grade the strength of evidence for each selected outcome separately. … In these situations, a grade of “insufficient” will be assigned.

427. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
     January 27, 2012 - evidence (SOE) as high, moderate, low, or insufficient based on established guidance.39 Developed to grade … Two reviewers assessed each domain for each key outcome and determined an overall SOE grade based on … In the event of disagreements on the domain or overall grade, they resolved differences by discussion

428. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
     October 27, 2017 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … Evidence for Each Key Question At the completion of our review, two reviewers will independently grade … In these situations, a grade of “insufficient” will be assigned.

429. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
     September 01, 2011 - dysplasia, neonatal death, death within initial hospitalization, significant intraventricular hemorrhage (grade … mean prolongation of pregnancy, bronchopulmonary dysplasia, significant intraventricular hemorrhage (grade … bronchopulmonary dysplasia, death within initial hospitalization, and significant intraventricular hemorrhage (grade … as bronchopulmonary dysplasia, necrotizing enterocolitis, significant intraventricular hemorrhage (grade

430. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - The entire approach corresponds to a great degree to that used in many organizations (namely, GRADE … This approach is very consistent with the GRADE approach (used in both the United States and abroad)

431. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
     February 22, 2012 - each KQ using the EPC method for intervention studies, which is based on methods developed by the GRADE

432. Colorectal-Cancer-Liver-Metastases-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
     December 01, 2012 - status (functional impairment typically defined by a higher Eastern Cooperative Oncology Group [ECOG] grade … based on a system developed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE … The strength of evidence grade can fall into one of four categories: high, moderate, low, and insufficient … The grade rating was made by independent reviewers, and disagreements were resolved by consensus adjudication … of Studies Risk of Bias Consistency Directness* Precision Overall Grade Overall Survival RFA 359,64,66

433. Disposition of Comments_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforce (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-disposition-comments.pdf
     February 28, 2025 - Disposition of Comments_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforce Systematic Review Disposition of Comments Report Title: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforce Draft report available …

434. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - Evidence-based Practice Center Systematic Review Protocol Project Title: Diagnosis of Right Lower Quadrant Pain (Suspected Acute Appendicitis) I. Background and Objectives for the Systematic Review Nature and burden of the condition Abdominal pain is a common presenting complaint for patients seeking care at…

435. Nutrition as Prevention for Improved Cancer Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
     December 01, 2021 - Comparisons and Outcomes Two investigators will independently assess five required domains (see below) to grade

436. Hypertension-Pulmonary-Arterial Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
     January 30, 2013 - Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome assessed … In these situations, a grade Source: www.effectivehealthcare.ahrq.gov Published online: January

437. Dementia-Nursing-Home-Characteristics Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
     October 01, 2012 - A grade of high SOE indicates we have high confidence that the evidence reflects the true effect.

438. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - Evidence-based Practice Center Systematic Review Protocol Project Title: Oral Mechanical Bowel Preparation for Colorectal Surgery I. Background and Objectives for the Systematic Review Nature and Burden of the Condition Oral mechanical bowel preparation (OMBP) is often prescribed preoperatively for patients hav…

439. Grading the Strength of a Body of Evidence When Assessing Health Care Interventions for the Effective Health Care Program of the Agency for Healthcare Research and Quality: An Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-grading-evidence/methods

440. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
     June 01, 2016 - *The overall evidence grade was assessed based on the ratings for the following domains: study limitations