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321. Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
     May 29, 2013 - Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations Comparative Effectiveness Research Review Disposition of Comments Report Research Review Title: Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special P…

322. Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician-2016.pdf
     January 01, 2016 - Effectiveness of Behavioral Programs for Managing T1DM ** The overall evidence grade was assessed based

323. Evidence Summary: CER 237_Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-237-evidence-summary-palliative-care-ambulatory.pdf
     February 01, 2021 - Evidence Summary: CER 237_Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness Comparative Effectiveness Review Number 237 Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness Evidence Summary Main Points Background and Purpose In the Unit…

324. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
     June 10, 2013 - weight- related outcomes together with each study contributing only one weight- related measure to the grade … The summary strength of evidence tables provide details about how we arrived at each grade. … the grading of evidence follows the recommendation in the AHRQ Methods guide which is based on the GRADE … consider both the quantity of literature and the quality of the literature when we assign an evidence grade … in the Executive Summary and in the main report: “We caution that a “high” strength of evidence grade

325. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
     August 07, 2012 - Grading the Evidence for Each Key Question - We will grade the overall strength of the body of evidence … Two reviewers will assess each domain and the overall grade for each key outcome listed in the PICOTS … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that

326. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - Peer Reviewer #3 Summary and Discussion (Pg 74 and following) I like the GRADE profiles but I think … Not everyone is familiar with GRADE. … The GRADE BMJ series might provide good citations. … The footnotes that GRADE tables usually have would be helpful to make the rationale for downgrading … A reference describing the GRADE profiles has been added.

327. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - Studies will be given a quality grade of good, fair, or poor per the established criteria for the … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence with disagreements resolved through

328. Tonsillectomy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
     February 10, 2016 - Intervention-­outcome  pairs  will  be  given  an  overall  evidence  grade  based  on  the  ratings   … We  assign  an  overall  grade  (high,  moderate,  low,  or  insufficient)  for  the  strength  of   … Strength  of  evidence  grades  and  definitions   Grade   Definition     High     We  are  very  confident … Two  senior  investigators  will  independently  grade  the  body  of  evidence,  with   disagreements … When  no  studies  are  available  for  an  outcome  or  comparison  of  interest,  we   will  grade  

329. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - The overall quality of evidence for outcomes will be assessed using a method developed by the Grade … Working Group,3 which classified the grade of evidence across outcomes according to the following criteria

330. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
     January 30, 2020 - Each specific adverse event will be graded for severity on a five-point scale, with grade 1 being mild … and grade 5 being death due to the event. … The strength of evidence domains are compatible with the GRADE group’s criteria to downgrade the quality … https://www.cdc.gov/vaccines/acip/recs/grade/HPV-adults-etr.html. … Food and Drug Administration GRADE Grading of Recommendations Assessment, Development and Evaluation

331. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - safety (e.g., sedation, dizziness, restless legs/akathisia, anxiety, and vomiting) outcomes using the Grade … For each key outcome for each comparison, we will assign an overall evidence grade based on the ratings

332. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
     March 11, 2010 - Introduction DCIS classifications use histologic grade, so the statement that only invasive tumors are … described by histologic grade is inaccurate.

333. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - publication bias.56 Grading the Strength of Evidence for Individual Comparisons and Outcomes: We will grade … the strength of evidence based on the guidance established for the EPC Program.57 Developed to grade … the Technical Expert Panel (TEP) to determine minimally important differences, which we will use to grade … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers

334. Methods Research Report Improving Access To And Usability of Systematic Review Data for Health Systems Guideline Development (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
     February 01, 2019 - Allows drill down • Uses fields, terms and tools common in systematic reviews • Follows popular GRADE … investment in MAGICapp to add AHRQ “strength of evidence” criteria to the platform or convert to GRADE … MAGICapp was developed based on Grading of Recommendations Assessment, Development and Evaluation (GRADE … alternatives versus the standard Grading of Recommendations Assessment, Development and Evaluation (GRADE … The GRADE format was mentioned by one reviewer as being helpful for both assessing and developing his

335. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
     March 19, 2018 - Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Draft review availa…

336. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - performance (Academic Performance Rating Scale Academic Competency Evaluation Scale (ACES), school grades, grade … determining strength of evidence for each primary clinical outcome by following the principles for adapting GRADE … unmeasured confounders) as described in the AHRQ Methods guides.95 A final strength of evidence grade … The strength of evidence will be assigned an overall grade of high, moderate, low, or insufficient

337. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - GRADE guidelines: 2. Framing the question and deciding on important outcomes. … GRADE guidelines: 6. Rating the quality of evidence—imprecision. … GRADE guidelines: 8. Rating the quality of evidence—indirectness. … GRADE guidelines: 7. Rating the quality of evidence—inconsistency. … GRADE guidelines: 5. Rating the quality of evidence—publication bias.

338. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - A statement should be included here that biopsy Gleason grade may sometimes underestimate the true Gleason … grade of the tumor ES-3 “The key finding of the analysis was that the Prostate Cancer Intervention … may sometimes underestimate the true Gleason grade of the tumor.” … Page 15 – Did lowering the evidence grade by one level as described here actually affect any of the … Methods Guide.”6 Pg. 15 It did not affect any of the outcomes listed in the strength of evidence grade

339. Infantile-Hemangioma Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
     January 01, 2016 - Intervention Type/ Number of Studies (Total N Participants) Key Outcome(s) Strength of Evidence (SOE) Grade … Intervention Type/ Number of Studies (Total N Participants) Key Outcome(s) Strength of Evidence (SOE) Grade … Intervention Type/ Number of Studies (Total N Participants) Key Outcome(s) Strength of Evidence (SOE) Grade … Intervention Type/ Number of Studies (Total N Participants) Key Outcome(s) Strength of Evidence (SOE) Grade … Intervention Type/ Number of Studies (Total N Participants) Key Outcome(s) Strength of Evidence (SOE) Grade

340. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes: We will grade the strength … of the body of evidence (SOE) as per the EPC methods guide on assessing SOE.28 We will grade SOE for