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281. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
     January 12, 2012 - Grading the Evidence for Each Key Question We will grade the strength of evidence on the basis … of guidance established for the EPC Program. 35 Developed to grade the overall strength of a body … Two reviewers will assess each domain and the overall grade for each key outcome listed in the framework … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that

282. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
     November 03, 2011 - Grading the Evidence for Each Key Question - We will grade the strength of evidence based on the guidance … established for the Evidence-based Practice Center (EPC) Program. 44 Developed to grade the overall … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al., 2010 44 We will grade the strength of evidence for the outcomes deemed to be

283. Methods Research Report: Improving Health Systems' Access to High-Quality Evidence: AHRQ EPC 2018 Pilot Projects Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-improving-health-systems-access.pdf
     August 01, 2019 - guidance previously published by Grades of Recommendation Assessment, Development and Evaluation (GRADE … The health system decision aid was developed based off the EtD framework by GRADE,6 and includes information …      7 Summary of findings table        7 Evidence table       6 GRADE … GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed … GRADE table of SOE grades: (Summarizes the body evidence for selected outcomes and include the GRADE

284. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - We did not grade evidence for harms, and therefore would not have been able to state that evidence

285. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - We did not grade evidence for harms, and therefore would not have been able to state that evidence

286. Methods Guide Atkins (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
     January 01, 2011 - treatments and outcomes.”3 The Grading of Recommendations Assessment, Development and Evaluation (GRADE … Applicability Is Best Reported Separately From the Strength of a Body of Evidence GRADE incorporates … Epidemiologic studies indicate that prostate cancer prognosis is tied to grade and, to a lesser extent … Results may not be applicable to current practices due to the evolving techniques in both stage and grade … be limited to men under 65 years of age but is not dependent on baseline PSA level or histologic grade

287. Methods-Guidance-Applicability Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
     January 01, 2011 - treatments and outcomes.”3 The Grading of Recommendations Assessment, Development and Evaluation (GRADE … Applicability Is Best Reported Separately From the Strength of a Body of Evidence GRADE incorporates … Epidemiologic studies indicate that prostate cancer prognosis is tied to grade and, to a lesser extent … Results may not be applicable to current practices due to the evolving techniques in both stage and grade … be limited to men under 65 years of age but is not dependent on baseline PSA level or histologic grade

288. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - outcomes was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE … ) system.21 GRADE addresses four domains of evidence (risk of bias, consistency, directness, and precision

289. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
     April 18, 2012 - Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … In these situations, a grade of “insufficient” will be assigned. … ≥ 90 days Timing Hospital inpatient setting Setting Study design Randomized trials We will grade

290. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
     March 29, 2011 - Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed

291. Communication and Dissemination Strategies To Facilitate the Use of Health-Related Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
     November 01, 2013 - Two reviewers also independently derived the overall strength-of-evidence grade, resolving conficts

292. Executive Summary_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
     May 01, 2025 - Executive Summary_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review Systematic Review Blood-Based Tests for Multiple Cancer Screening: A Systematic Review Executive Summary Main Points • No completed studies show if blood-based, multicancer screening tests help people co…

293. Attention Deficit Hyperactivity Disorder: Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
     October 01, 2011 - already identified at an early age, preschool youngsters with ODD frequently meet criteria for ADHD by grade … Body of Evidence We assessed the overall strength of the body of evidence using the context of the GRADE … Our results using the GRADE approach to assign SOE are summarized in Table A. … Our results using the GRADE approach to assign SOE are summarized in Table B. … Grade Working Group. Grading the Quality of Evidence and the Strength of Recommendations.

294. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
     February 05, 2025 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes: We will grade the SOE for … General and social functioning • Disability • Depression • Anxiety • Adverse events We will grade … The SOE will be assigned an overall 9 grade of high, moderate, low, or insufficient according … GRADE guidelines 6. Rating the quality of evidence-- imprecision.

295. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
     September 25, 2024 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes: We will grade the SOE for … General and social functioning • Disability • Depression • Anxiety • Adverse events We will grade … The SOE will be assigned an overall grade of high, moderate, low, or insufficient according … GRADE guidelines 6. Rating the quality of evidence-- imprecision.

296. Binge-Eating Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_research-protocol.pdf
     July 21, 2014 - Grading the Strength of Evidence for Individual Comparisons and Outcomes: We will grade the strength … updated guidance established for the Evidence-based Practice Center (EPC) program.68 Developed to grade … members of the review team (including at least one subject matter expert and one methodologist) will grade … Definitions of the grades of overall strength of evidence68 Grade Definition We are very confident

297. Organisation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_appendixes.pdf
     June 16, 2008 - Conformal proton radiation therapy for pediatric low-grade astrocytomas. … Radiotherapy for chordomas and low-grade chondrosarcomas of the skull base with carbon ions. … Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base. … Pion radiation for high grade astrocytoma: results of a randomized study. … Successful use of intracavitary bleomycin for low- grade astrocytoma tumor cyst.

298. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - publication bias.56 Grading the Strength of Evidence for Individual Comparisons and Outcomes: We will grade … the strength of evidence based on the guidance established for the EPC Program.57 Developed to grade … the Technical Expert Panel (TEP) to determine minimally important differences, which we will use to grade … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers

299. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWH vs. … Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWHvs. … Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWH vs. … Studies (N) Estimates Conclusions SoE Grade LMWH vs. … Studies (N) Summary OR (95% CI Conclusions SoE Grade FXaI low vs.

300. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWH vs. … Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWHvs. … Studies (N) Summary OR (95% CI) or Range of Estimates† Conclusions SoE Grade LMWH vs. … Studies (N) Estimates Conclusions SoE Grade LMWH vs. … Studies (N) Summary OR (95% CI Conclusions SoE Grade FXaI low vs.