-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - childhood is associated with improved reading achievement, decreased school
absenteeism, and decreased grade … grades, scores on standardized test), lower rates
of graduation from high school, higher rates of grade … outcome well but did an incomplete analysis of a secondary outcome would be assigned a
different quality grade … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes
We will grade the strength … In these situations, a
grade of “insufficient” will be assigned.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - investigators will independently assess five required domains (listed below) and other
possible factors to grade … For treatment comparisons, the starting SOE grade for an evidence base derived from RCTs will
be high … , while the starting SOE grade for an evidence based derived from observational studies
will be low. … For diagnostic tests, the starting SOE grade for an evidence base will be high.28 The
final SOE grades
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - Grading the Strength of Evidence for Major Comparisons and Outcomes
We will grade the SOE based on … the guidance established for the Evidence-based Practice Center
(EPC) Program.45 Developed to grade … Definitions of the grades of overall SOE46
Grade Definition
High High confidence that the evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
October 01, 2021 - each outcome, the number of trials, the heterogeneity statistic (I2), and the
strength of evidence grade … 95 percent confidence interval, as well as the number of trials, I-square, and strength of
evidence grade … risk with upper and lower limit of the confidence interval, I-
square value, and strength of evidence grade
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome … In these
situations, a grade of “insufficient” will be assigned.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Each key outcome on each comparison of interest will be given an overall
evidence grade based on the … Two senior staff will independently grade the body of evidence, with disagreements resolved
through
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - Comparator
Number/Type of
Studies (Total N
Participants)
Key
Outcome(s)
Strength of Evidence
Grade … Comparator
Number/Type of
Studies (Total N
Participants)
Key
Outcome(s)
Strength of Evidence
Grade … Comparator
Number/Type of
Studies (Total N
Participants)
Key
Outcome(s)
Strength of Evidence
Grade … Comparator
Number/Type of
Studies (Total N
Participants)
Key
Outcome(s)
Strength of Evidence
Grade … Comparator
Number/Type of
Studies (Total N
Participants)
Key
Outcome(s)
Strength of Evidence
Grade
-
effectivehealthcare.ahrq.gov/sites/default/files/fleisher.pdf
January 01, 2010 - below basic health
literacy skills
• Average reading level for U.S. adults is at or below 8th grade … www.temple.edu.chpsw/departments/publichealth/PH_RiskCommLab.htm
• Touch screen
• Written at a 6th grade
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - CER 220 Evidence Summary: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting
Purpose of Review
To evaluate effectiveness and harms of opioids compared to
nonopioid analgesics as treatment of moderate to severe acute
pain in the prehospital setting.
Key Messages
• As initial…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
April 01, 2012 - The STAR*D trial contributed
to many of the comparisons and affected the final grade in
this treatment … therapies relative to
other combined therapies were grouped as one category for
grading SOE; the overall grade … There is
low-grade evidence that comparable results are achieved
following the switch to an alternate … There is
low-grade evidence that adding an atypical antipsychotic
medication to ongoing SSRI treatment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - Chapter 11 in the Methods Reference Guide for Effectiveness and
Comparative Effectiveness Reviews to grade
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obsessive-compulsive-disorder-disposition-comments.pdf
December 06, 2024 - Disposition of Comments_Comparative Effectiveness Review No. 276: Diagnosis and Managment of Obsessive Compulsive Disorders in Children
Source: https://effectivehealthcare.ahrq.gov/products/obsessive-compulsive-disorder/research
Published on-line: December 6, 2024
Comparative Effectiveness Review Dispos…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - determining strength of evidence for
each primary clinical outcome by following the principles for adapting GRADE … unmeasured confounders) as described in the
AHRQ Methods guides.18,22
A final strength of evidence grade … The
strength of evidence will be assigned an overall grade of high, moderate, low, or
insufficient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
January 15, 2015 - adapting GRADE (Grading of Recommendations Assessment, Development and
Evaluation) outlined in the AHRQ … unmeasured confounders) as described in the AHRQ methods
guides.15, 18
A final strength of evidence grade … The
strength of evidence will be assigned an overall grade of high, moderate, low, or
insufficient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a
different quality grade … Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome assessed … In these situations, a grade of “insufficient” will be
assigned.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - We will take the limitations of certain study designs into consideration
when we grade the strength … selection modeling.71
Grading the Strength of Evidence for Major Comparisons and Outcomes
We will grade … the strength of evidence based on the guidance established for the EPC
Program.69 Developed to grade … not assess the risk of bias of noncontrolled or single-group
pre/post studies, we plan also not to grade … Definition'of'strength'of'evidence'grades'
Grade' Definition'
High! We!are!very!confident!that!
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - using guidance outlined in the Methods Guide.10 This method is based loosely on one
developed by the Grade … Working Group and classifies the grade of evidence according
to the following criteria:
High = … Source: www.effectivehealthcare.ahrq.gov
Published Online: June 23, 2011
12
The evidence grade
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
January 01, 2010 - We assigned evidence grades for each outcome as
follows: (1) high grade (indicating high confidence … research may change our confidence in
the estimate of the effect and may change the estimate);
(3) low grade … Although we did not grade the evidence for indirect
outcomes, we observed that subcutaneous immunotherapy … There is high-grade evidence that subcutaneous
immunotherapy reduces asthma symptoms and asthma
medication … There is high-grade
evidence that sublingual immunotherapy reduces asthma
symptoms.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
January 12, 2012 - Grading the Evidence for Each Key Question
We will grade the strength of evidence on the basis … of guidance established for the EPC
Program.
35
Developed to grade the overall strength of a body … Two reviewers will assess each domain and the overall grade for each key outcome listed
in the framework … Definitions of the grades of overall strength of evidence
Grade Definition
High High confidence that
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-nursing-home-characteristics_research-protocol.pdf
November 03, 2011 - Grading the Evidence for Each Key Question - We will grade the strength
of evidence based on the guidance … established for the Evidence-based Practice
Center (EPC) Program.
44
Developed to grade the overall … Definitions of the grades of overall strength of evidence
Grade Definition
High High confidence that … Source: Owens et al., 2010
44
We will grade the strength of evidence for the outcomes deemed to be