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241. Use of a Clinical Pathway To Facilitate the Translation and Utilization of AHRQ EPC Report Findings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/clinical-pathway-methods-report.pdf
     December 01, 2018 - The use of any standardized system to grade the evidence supporting a recommendation is acceptable for … The use of any standardized system to grade the strength of a recommendation is acceptable for purposes … Numerous scales are already available, such as the one from the GRADE Working Group (5). … GRADE: Going from evidence to recommendations. BMJ. 2008;336(7652):1049-51.

242. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - A grade of high SOE indicates that we have high confidence that the evidence reflects the true effect … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons … cessation and healthy eating outcomes, and two studies enrolling office workers contributed to our SOE grade … concurrent control group, but limiting by study design is unlikely to have had a major effect on our SOE grade

243. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
     April 01, 2020 - For bodies of evidence for which we could conduct sensitivity analyses, we based the final SOE grade … We appended a footnote to SOE tables to indicate when sensitivity analyses changed the SOE grade. … baseline or followup control arms ranges from 4.031 to 5.7.29 b Without high risk-of-bias studies, the grade

244. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
     August 24, 2011 - Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence, with disagreements resolved through

245. VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
     January 30, 2014 - “domains” and then combine domain scores into an overall grade. … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed … Individual comparisons and outcomes We will give an overall evidence grade based on the ratings for … When no studies are available for an outcome or comparison of interest, we will grade the evidence as … Strength of evidence grades and definitions Grade Definition High We are very confident that the estimate

246. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf
     October 01, 2021 - each outcome, the number of trials, the heterogeneity statistic (I2), and the strength of evidence grade … 95 percent confidence interval, as well as the number of trials, I-square, and strength of evidence grade … risk with upper and lower limit of the confidence interval, I- square value, and strength of evidence grade

247. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
     December 20, 2011 - We will grade the strength of evidence based on the guidance established for the Evidence-based Practice … Center Program. 26 Developed to grade the overall strength of a body of evidence, this approach … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers … Definitions of the grades of overall strength of evidence 26 Grade Definition High High confidence

248. Disposition of Comments Report for Procalcitonin-Guides Antibiotic Therapy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
     October 05, 2012 - helpful to refer to Table ES-2 in the ES (page ES-6, line 37) where the ES describes the elements of GRADE … Affiliation Section Comment Response PR (#3) Results Critically III/Ventilator-Associated Pneumonia The grade

249. Major-Depressive-Disorder Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
     December 01, 2015 - the Key Informants to rank the relative importance of outcomes following a process proposed by the GRADE … GRADE guidelines: 2. Framing the question and deciding on important outcomes.

250. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment_research-protocol.pdf
     September 29, 2011 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient

251. Research Protocol for Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
     October 02, 2018 - Grading the Strength of Evidence for Major Comparisons and Outcomes We will grade the strength of … evidence “any estimate of effect is very uncertain,” the definition of Very Low quality evidence per GRADE … GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.

252. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
     October 18, 2010 - Online: October 18, 2010 6 necrotizing enterocolitis, significant intraventricular hemorrhage (grade … delivery • PPI Neonatal Outcomes* • Bronchopulmonary dysplasia • Necrotizing enterocolitis • Grade … Bronchopulmonary dysplasia • Necrotizing enterocolitis • Significant intraventricular hemorrhage (grade … KQ1: bronchopulmonary dysplasia, necrotizing enterocolitis, significant intraventricular hemorrhage (grade … mean prolongation of pregnancy; bronchopulmonary dysplasia; significant intraventricular hemorrhage (grade

253. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
     January 01, 2010 - Grading the Evidence for Each Key Question At the completion of our review, we will grade the strength … We will classify evidence pertaining to KQs 1 and 2 into four basic categories: 1) “high” grade (indicating … research is very unlikely to change our confidence in the estimate of the effect); 2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); 3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and 4) “insufficient” grade

254. Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
     May 01, 2016 - Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the effectiveness, comparative effectiv…

255. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
     November 26, 2024 - For the Key Questions on consequences of misuse, we will use the GRADE (Grading of Recommendations, … Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework

256. Management of Postpartum Hemorrhage: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
     July 01, 2016 - * The overall evidence grade was assessed based on the ratings for the following domains: study limitations

257. Bladder-Cancer-Non-Muscle-Invasive Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
     July 21, 2014 - These include the stage of the cancer, tumor grade, whether the tumor is an initial tumor or a recurrence … risk-adapted approach to treatment decision-making, based on available prognostic factors including grade … the comparative effectiveness differ according to tumor characteristics, such as histology, stage, grade … the comparative effectiveness differ according to tumor characteristics, such as histology, stage, grade … The strength of evidence will be assigned an overall grade of high, moderate, low, or insufficient according

258. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alternative-payment-models-protocol.pdf
     December 16, 2024 - evidence criteria, informed by Grading of Recommendations Assessment, Development, and Evaluation (GRADE … A final strength of evidence grade for each evidence statement for all key outcomes within the key questions … We will differentiate an overall grade of high, moderate, low, or insufficient according to a four-level … GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence.

259. Measuring-Blood-Pressure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
     January 01, 2012 - For treatment studies, only RCTs may receive a grade of A. B (fair/moderate).

260. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
     October 01, 2021 - each outcome, the number of trials, the heterogeneity statistic (I2), and the strength of evidence grade … 95 percent confidence interval, as well as the number of trials, I-square, and strength of evidence grade … risk with upper and lower limit of the confidence interval, I- square value, and strength of evidence grade