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221. Renal-Function Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
     June 13, 2013 - We will grade the strength of evidence based on the quantity, quality, and consistency of the best available … We will classify evidence pertaining to the KQs into four basic categories: 1) “high” grade (indicating … research is very unlikely to change our confidence in the estimate of the effect); 2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); 3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and 4) “insufficient” grade

222. Evidence-based Practice Center Systematic Review Protocol: Malnutrition in Hospitalized Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/malnutrition-hospitalized-adults-protocol.pdf
     October 19, 2020 - Evidence-based Practice Center Systematic Review Protocol: Malnutrition in Hospitalized Adults Evidence-based Practice Center Systematic Review Protocol Project Title: Malnutrition in Hospitalized Adults I. Background and Objectives for the Systematic Review Malnutrition among hospitalized patients remain…

223. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
     June 01, 2013 - by consensus discussion; the same reviewers also used the domain scores to assign an overall SOE grade … Further, based on GRADE guidelines on assessing the risk of bias,34 when the evidence was generated … The grade of evidence strength was classified into the following four categories: • High. … program and referenced in the Methods Guide.29 This approach is based on a system developed by the GRADE … GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias).

224. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
     January 30, 2012 - Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … In these situations, a grade of “insufficient” will be assigned.

225. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol.pdf
     September 13, 2024 - For the Key Questions on consequences of misuse, we will use the GRADE (Grading of Recommendations, … Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework

226. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - emotional skills) and educational achievement; kindergarten readiness; age at kindergarten entry; third grade … testing outcomes; other standard testing outcomes (eighth grade, etc … Chapter 10 of the AHRQ “Methods Guide for Effectiveness and Comparative Effectiveness Reviews”20,28 to grade … Based on this assessment, reviewers assigned the body of evidence a strength-of-evidence grade of high … which evidence did not exist, was sparse, or contained irreconcilable inconsistency, we assigned a grade

227. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
     December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 7, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Therapies for Children with Autism Spectrum Disorders I. Backgrou…

228. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
     January 01, 2010 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 7, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Therapies for Children with Autism Spectrum Disorders I. Backgrou…

229. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - therapies relative to other combined therapies were grouped as one category for grading SOE; the overall grade … therapies relative to other combined therapies were grouped as one category for grading SOE; the overall grade

230. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
     July 01, 2010 - Quality of Individual Studies We will use an internal validity rating scale for diagnostic studies to grade … The grade will be developed by considering four important domains: the risk of bias in the evidence

231. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
     January 01, 2021 - Hu 2020 China NR Community center(s) Inclusion: Greater than or equal to grade 1 out of maximum 4 grades … : NR Race: NR Duration of symptoms: NR Pain etiology/type or diagnostic classification: Knee OA (KL grade … 2: 50% vs. 51% vs. 46% - KL grade 3 : 39% vs. 38% vs. 46% - KL grade 4: 11% vs. 11% vs. 8% Hypertension … Scale - Back Disability (CPGS-BD) Chronic Pain Grade Scale - Back Pain (CPGS-BP) Chronic Pain Grade … Scale - Neck Disability (CPGS-ND) Chronic Pain Grade Scale - Neck Pain (CPGS-NP) Defense & Veterans

232. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
     January 01, 2021 - Hu 2020 China NR Community center(s) Inclusion: Greater than or equal to grade 1 out of maximum 4 grades … : NR Race: NR Duration of symptoms: NR Pain etiology/type or diagnostic classification: Knee OA (KL grade … 2: 50% vs. 51% vs. 46% - KL grade 3 : 39% vs. 38% vs. 46% - KL grade 4: 11% vs. 11% vs. 8% Hypertension … Scale - Back Disability (CPGS-BD) Chronic Pain Grade Scale - Back Pain (CPGS-BP) Chronic Pain Grade … Scale - Neck Disability (CPGS-ND) Chronic Pain Grade Scale - Neck Pain (CPGS-NP) Defense & Veterans

233. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
     February 16, 2016 - We assign an overall grade (high, moderate, low or insufficient) for the strength of evidence for each … Strength of evidence grades and definitions Grade   Definition     High     Very  confident  that  the … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed … When no studies are available for an outcome or comparison of interest, we will grade the evidence … When no studies are available for an outcome or comparison of interest, we will grade the evidence as

234. Nephropathy-Contrast-Induced Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
     October 01, 2013 - Individual Comparisons and Outcomes – At the completion of this review, two reviewers will independently grade … effect).42 We will classify the evidence pertaining to the key questions into four categories: high grade … and further research is very unlikely to change our confidence in the estimate of effect); moderate grade … reflects the true effect, and further research may change our confidence in the estimate of effect); low grade … confidence in the estimate of the effect and is likely to change the effect estimate); and insufficient grade

235. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
     February 22, 2012 - primary authors concur that, if obtained, evidence could impact results meaningfully (i.e., alter GRADE … overall body of evidence is outlined in the Methods Guide27 and is based on a system developed by the GRADE … The grade of evidence strength is classified into the following four categories: • High. … The grade rating will be made by independent reviewers, and disagreements will be resolved by consensus

236. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - Peer Reviewer #6 Introduction Introduction: Page 33: the word grade has been dropped, use stage or … The NPUAP has now adopted the term "Stage" rather than "Grade". … For further details about modification to GRADE and rationale please see the EPC Methods Guide at http … Also there is no grade V. … a more advanced static support surface (an air suspension bed) associated with decreased risk of grade

237. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
     September 01, 2011 - Please read the paper by Owens at al we referenced for the methodology we followed to grade the strength

238. App-D-Surv-Report-3-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
     January 01, 2022 - Hu 2020 [Surveillance Report 1] China NR Community center(s) Inclusion: Greater than or equal to grade … : NR Race: NR Duration of symptoms: NR Pain etiology/type or diagnostic classification: Knee OA (KL grade … of knee osteoarthritis according to the American College of Rheumatology (ACR) diagnostic criteria; grade … 2: 50% vs. 51% vs. 46% - KL grade 3 : 39% vs. 38% vs. 46% - KL grade 4: 11% vs. 11% vs. 8% Hypertension … Scale - Back Disability (CPGS-BD) Chronic Pain Grade Scale - Back Pain (CPGS-BP) Chronic Pain Grade

239. Allergy-Seasonal Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
     July 01, 2013 - evaluated separately for each treatment comparison and each outcome of interest to derive a single GRADE … • A high GRADE indicates high confidence that the evidence reflects the true effect. … • A moderate GRADE indicates moderate confidence that the evidence reflects the true effect. … • A low GRADE indicates low confidence that the evidence reflects the true effect. … Decision rules used to assess each GRADE domain are provided in the full report.

240. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - The National Cancer Institute and others classify anemia based on hemoglobin (Hb) values: 6 • Grade … normal limits, hemoglobin values are 12.0 to 16.0 g/dL for women and 14.0 to 18.0 g/dL for men • Grade … 1, mild (Hb 10 g/dL to normal limits) • Grade 2, moderate (Hb 8.0 to 10.0 g/dL) • Grade 3, serious … /severe (Hb 6.5 to 7.9 g/dL) • Grade 4, life threatening (Hb less than 6.5 g/dL). … Working Group.57 The GRADE system explicitly addresses the following domains: risk of bias, consistency