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221. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
     June 01, 2013 - by consensus discussion; the same reviewers also used the domain scores to assign an overall SOE grade … Further, based on GRADE guidelines on assessing the risk of bias,34 when the evidence was generated … The grade of evidence strength was classified into the following four categories: • High. … program and referenced in the Methods Guide.29 This approach is based on a system developed by the GRADE … GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias).

222. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol.pdf
     September 13, 2024 - For the Key Questions on consequences of misuse, we will use the GRADE (Grading of Recommendations, … Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework

223. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
     January 30, 2012 - Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … In these situations, a grade of “insufficient” will be assigned.

224. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
     July 01, 2014 - emotional skills) and educational achievement; kindergarten readiness; age at kindergarten entry; third grade … testing outcomes; other standard testing outcomes (eighth grade, etc … Chapter 10 of the AHRQ “Methods Guide for Effectiveness and Comparative Effectiveness Reviews”20,28 to grade … Based on this assessment, reviewers assigned the body of evidence a strength-of-evidence grade of high … which evidence did not exist, was sparse, or contained irreconcilable inconsistency, we assigned a grade

225. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
     December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 7, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Therapies for Children with Autism Spectrum Disorders I. Backgrou…

226. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
     January 01, 2010 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 7, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Therapies for Children with Autism Spectrum Disorders I. Backgrou…

227. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - therapies relative to other combined therapies were grouped as one category for grading SOE; the overall grade … therapies relative to other combined therapies were grouped as one category for grading SOE; the overall grade

228. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
     July 01, 2010 - Quality of Individual Studies We will use an internal validity rating scale for diagnostic studies to grade … The grade will be developed by considering four important domains: the risk of bias in the evidence

229. Nephropathy-Contrast-Induced Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
     October 01, 2013 - Individual Comparisons and Outcomes – At the completion of this review, two reviewers will independently grade … effect).42 We will classify the evidence pertaining to the key questions into four categories: high grade … and further research is very unlikely to change our confidence in the estimate of effect); moderate grade … reflects the true effect, and further research may change our confidence in the estimate of effect); low grade … confidence in the estimate of the effect and is likely to change the effect estimate); and insufficient grade

230. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
     February 16, 2016 - We assign an overall grade (high, moderate, low or insufficient) for the strength of evidence for each … Strength of evidence grades and definitions Grade   Definition     High     Very  confident  that  the … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed … When no studies are available for an outcome or comparison of interest, we will grade the evidence … When no studies are available for an outcome or comparison of interest, we will grade the evidence as

231. Liver-Cancer-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
     November 28, 2012 - authors concur that if obtained, evidence could impact results meaningfully (i.e., alter evidence GRADE … EPC approach, which is outlined in the Methods Guide43 and is based on a system developed by the GRADE … The grade of evidence strength is classified into the following four categories: • High. … The grade rating will be made by independent reviewers, and disagreements will be resolved by consensus

232. Medication-Therapy-Management Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
     January 01, 2014 - Grading the Strength of Evidence for Individual Comparisons and Outcomes We will grade the strength … based on the guidance established for the Evidence- based Practice Center Program.17 Developed to grade … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers … Definitions of the grades of overall strength of evidence15 Grade Definition 19 Source: www.effectivehealthcare.ahrq.gov

233. Disposition of Comments Report for Pressure Ulcer Risk Assessment and Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
     May 08, 2013 - Peer Reviewer #6 Introduction Introduction: Page 33: the word grade has been dropped, use stage or … The NPUAP has now adopted the term "Stage" rather than "Grade". … For further details about modification to GRADE and rationale please see the EPC Methods Guide at http … Also there is no grade V. … a more advanced static support surface (an air suspension bed) associated with decreased risk of grade

234. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
     January 01, 2021 - Hu 2020 China NR Community center(s) Inclusion: Greater than or equal to grade 1 out of maximum 4 grades … : NR Race: NR Duration of symptoms: NR Pain etiology/type or diagnostic classification: Knee OA (KL grade … 2: 50% vs. 51% vs. 46% - KL grade 3 : 39% vs. 38% vs. 46% - KL grade 4: 11% vs. 11% vs. 8% Hypertension … Scale - Back Disability (CPGS-BD) Chronic Pain Grade Scale - Back Pain (CPGS-BP) Chronic Pain Grade … Scale - Neck Disability (CPGS-ND) Chronic Pain Grade Scale - Neck Pain (CPGS-NP) Defense & Veterans

235. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
     January 01, 2021 - Hu 2020 China NR Community center(s) Inclusion: Greater than or equal to grade 1 out of maximum 4 grades … : NR Race: NR Duration of symptoms: NR Pain etiology/type or diagnostic classification: Knee OA (KL grade … 2: 50% vs. 51% vs. 46% - KL grade 3 : 39% vs. 38% vs. 46% - KL grade 4: 11% vs. 11% vs. 8% Hypertension … Scale - Back Disability (CPGS-BD) Chronic Pain Grade Scale - Back Pain (CPGS-BP) Chronic Pain Grade … Scale - Neck Disability (CPGS-ND) Chronic Pain Grade Scale - Neck Pain (CPGS-NP) Defense & Veterans

236. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
     September 01, 2011 - Please read the paper by Owens at al we referenced for the methodology we followed to grade the strength

237. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - The National Cancer Institute and others classify anemia based on hemoglobin (Hb) values: 6 • Grade … normal limits, hemoglobin values are 12.0 to 16.0 g/dL for women and 14.0 to 18.0 g/dL for men • Grade … 1, mild (Hb 10 g/dL to normal limits) • Grade 2, moderate (Hb 8.0 to 10.0 g/dL) • Grade 3, serious … /severe (Hb 6.5 to 7.9 g/dL) • Grade 4, life threatening (Hb less than 6.5 g/dL). … Working Group.57 The GRADE system explicitly addresses the following domains: risk of bias, consistency

238. Allergy-Seasonal Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
     July 01, 2013 - evaluated separately for each treatment comparison and each outcome of interest to derive a single GRADE … • A high GRADE indicates high confidence that the evidence reflects the true effect. … • A moderate GRADE indicates moderate confidence that the evidence reflects the true effect. … • A low GRADE indicates low confidence that the evidence reflects the true effect. … Decision rules used to assess each GRADE domain are provided in the full report.

239. Use of a Clinical Pathway To Facilitate the Translation and Utilization of AHRQ EPC Report Findings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/clinical-pathway-methods-report.pdf
     December 01, 2018 - The use of any standardized system to grade the evidence supporting a recommendation is acceptable for … The use of any standardized system to grade the strength of a recommendation is acceptable for purposes … Numerous scales are already available, such as the one from the GRADE Working Group (5). … GRADE: Going from evidence to recommendations. BMJ. 2008;336(7652):1049-51.

240. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - A grade of high SOE indicates that we have high confidence that the evidence reflects the true effect … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons … cessation and healthy eating outcomes, and two studies enrolling office workers contributed to our SOE grade … concurrent control group, but limiting by study design is unlikely to have had a major effect on our SOE grade