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181. Disposition of Comments Report for Interventions To Modify Health Care Provider Adherence to Asthma Guidelines (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-provider-adherence_disposition-comments.pdf
     May 19, 2013 - The procedure for incorporating the multiple domains into the strength of evidence grade (perhaps the … the approach used to synthesize the information in each domain to reach the strength of evidence grade … consistency and precision), each of which could contribute to varying degrees the assignment of a grade … Further, an “insufficient” grade indicates an area where we are unable to make conclusions based on … The insufficient grade was primarily for studies evaluating missed school/work.

182. Topic 0502 Non-Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
     March 06, 2013 - How do tumor characteristics (stage, grade, multiplicity, size, molecular and genetic alterations)

183. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
     October 12, 2015 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … Brown EPC.62 Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade … the body of evidence for a particular outcome includes both RCTs and observational studies, we will grade … In these situations, a grade of “insufficient” will be assigned. … reproductive technology BMI body mass index GI gastrointestinal GnRH gonadotropin-releasing hormone GRADE

184. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
     November 01, 2010 - We will use the system for rating the strength of the overall body of evidence developed by the GRADE … Grade of evidence strength is classified into the following four categories: • High quality: Further … GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. … free survival was abstracted and summarized in the appendix but will not be synthesized for the GRADE … captured in overall survival we decided to use overall survival as the basis for our synthesis and GRADE

185. Partial Breast Irradiation for Breast Cancer: Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
     August 09, 2021 - features that were included in clinical trials of PBI, such as larger tumor size (2-3 cm), high tumor grade … Nodal assessment (i.e., sentinel lymph node biopsy, axillary lymph node dissection, none) • Tumor grade … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade the strength … RCTs start with a provisional high SOE grade, while observational studies start with a provisional low … SOE grade.28 The domains to be used for determining final SOE grade will be: the methodological limitations

186. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
     December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 9, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Traumatic Brain Injury and Depression I. Background and Objectives…

187. Fecal-Incontinence Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
     November 30, 2014 - strength of evidence methods must meet accepted AHRQ EPC standards (such as Cochrane review methods or GRADE … Deficiencies in the five domains will lower the strength of evidence grade.43 We will require the existence … For published systematic reviews that did not provide a strength of evidence assessment based on a GRADE … or GRADE- equivalent method, we will assess strength of evidence by replacing de novo review processes

188. The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
     January 01, 2023 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade the strength … of the body of evidence (SOE) per the EPC methods guide on assessing SOE.34 We will grade SOE for end

189. Disposition of Comments for CER 167 Renal Masses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
     February 24, 2016 - Consider, "rates of major complications (Clavien grade 3 - 5)". As an aside, is the word 7. … RCC, and then took the percentage of those for which grade could be assigned (shown to be 67.3%) to … show that a proportion of RCCs did not have grade assigned at biopsy. … Then, among patients with surgical pathology available, we compared final tumor grade to biopsy grade … can be assigned (Results, KQ2, Fuhrman Grade). 15.

190. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quality-gap-palliative-hospice_research-protocol.pdf
     June 27, 2011 - We will use an evidence grading scheme recommended by the GRADE Working Group, which has been adapted … evaluated by at least one randomized controlled trial in addition to observational studies, our evidence grade … If an outcome has not been evaluated in any randomized controlled trial, our evidence grade will be … precision as described in the Methods Guide. 18,19 For each outcome of interest, two investigators will grade

191. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - Grading the Evidence for Each Key Question We will grade the strength of evidence for primary outcomes … as outlined in the Methods Guide for Effectiveness and Comparative Effectiveness Reviews.20,21 The grade … Strength of evidence grades and definitions Grade Definition High High confidence that the evidence

192. Fractional Exhaled Nitric Oxide Clinical Utility in Asthma Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nitric-oxide_research-protocol.pdf
     September 06, 2016 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade the strength … We will grade the strength of evidence for the outcomes we classified as most important or critical … Independent reviewers, working in pairs, will grade the SOE and resolve the conflicts by discussion

193. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
     September 29, 2010 - reviews of treatment interventions, where appropriate the grading system will be modified following the GRADE … GRADE: Grading the quality of evidence and strength of recommendations for diagnostic tests and strategies

194. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
     June 06, 2011 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient

195. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
     August 18, 2011 - We will grade the strength of evidence based on the guidance established by the Evidence-based Practice … Center (EPC) program. 49 Developed to grade the overall strength of a body of evidence, this approach … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers … Definitions of the grades of overall strength of evidence 49 Grade Definition High High confidence

196. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - Two independent reviewers graded the body of evidence using the Evidence-based Practice Center (EPC) GRADE

197. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
     August 19, 2011 - well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … Grading the Evidence for Each Key Question We will follow the AHRQ Methods Guide to grade the strength

198. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
     May 01, 2013 - Grade B recommendation for screening “when staff-assisted depression care supports are in place to … assure accurate diagnosis, effective treatment, and follow-up;” Grade C recommendation against screening … Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … In these situations, a grade of insufficient will be assigned. … Review Protocol Project Title: Efficacy and Safety of Screening for Postpartum Depression We will grade

199. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
     December 09, 2009 - Grading the Body of Evidence Where there are three or more studies, we will grade the body of evidence … outcomes using an adaptation of the Grading of Recommendation Assessment, Development & Evaluation (GRADE

200. ASSESSING THE QUALITY OF INCLUDED STUDIES (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
     June 02, 2011 - At that stage, EPCs generally give evidence derived from observational studies a low starting grade … and evidence from randomized controlled trials a high grade. … GRADE guidelines: 3. Rating the quality of evidence. Journal of Clinical Epidemiology. … GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. … GRADE guidelines: 4.