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161. labor-dystocia-protocol-amended-160728 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
     July 28, 2016 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … Brown EPC.25 Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade … the body of evidence for a particular outcome includes both RCTs and observational studies, we will grade … In these situations, a grade of “insufficient” will be assigned.

162. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
     October 22, 2012 - outcome well but did an incomplete analysis of a secondary outcome would be assigned a different quality grade … Grading the Evidence for Each Key Question We will grade the strength of evidence for each outcome … In these situations, a grade of insufficient will be assigned. … Center Systematic Review Protocol Project Title: Assessment and Management of Chronic Cough We will grade

163. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system is widely … of a Body of Evidence That Includes NRSIs The AHRQ EPC Program adopted a modified version of the GRADE … to the lack of randomization and higher potential for confounding.97 Thus, an initial provisional grade … Grade strength of evidence for NRSIs using established guidance. … GRADE guidelines: 3. Rating the quality of evidence.

164. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system is widely … of a Body of Evidence That Includes NRSIs The AHRQ EPC Program adopted a modified version of the GRADE … to the lack of randomization and higher potential for confounding.97 Thus, an initial provisional grade … Grade strength of evidence for NRSIs using established guidance. … GRADE guidelines: 3. Rating the quality of evidence.

165. heart-failure-readmission-protocol-130611 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
     June 10, 2013 - Grading the Strength of Evidence for Individual Comparisons and Outcomes We will grade the strength … based on the guidance established for the Evidence- based Practice Center (EPC) Program.47 Developed to grade … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al., 201047 We will grade the strength of evidence for all outcomes related to … We will not grade the evidence for KQ 3; this question is a descriptive question. G.

166. Alcohol-misuse-drug-therapy-140326 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
     January 27, 2012 - Grading the Strength of Evidence (SOE) for Individual Comparisons and Outcomes—We will grade the strength … based on the guidance established for the Evidence-based Practice Center Program.45 Developed to grade … We will grade the strength of evidence for alcohol-consumption measures, accidents, injuries, quality … Definitions of the grades of overall strength of evidence45 Grade Definition High High confidence

167. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - Abdul-Aziz and colleagues26 did not appraise the quality of individual studies or grade the quality … Grading the Strength of Evidence (SOE) for Individual Comparisons and Outcomes We will grade the … on the guidance established for the Evidence- based Practice Center (EPC) Program.33 Developed to grade … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al.33 We will grade the strength of evidence for the outcomes deemed to be of greatest

168. Lumbar-Fusion-Draft-Report-Appendix-D (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
     January 01, 2019 - Enrolled Sample Analyzed Sample Intervention Comparator Concomitant Therapies Diagnoses Spondylolisthesis Grade … B ASA grade 1: 8.9% (11/124) vs. 12.4% (16/129) 2: 71.0% (88/124) vs. 75.2% (97/129) 3: 20.2% (25/124 … 3 (10%) vs. 2 (6.6%) Grade 4: 18 (60%) vs. 19 vs. 16 Grade 5: 10 vs. 8 vs. 12 Fusion after 12 months … Grade 4: 4 vs. 7 vs. 4 Grade 5: 26 vs. 23 vs. 26 Surgery complications Limb paresis, n Group 1: 0 Group … 1 degenerative spondylolithesis Grade 1 NR NR Single-level fusions NR NR A vs.

169. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
     February 23, 2012 - Studies will be given a quality grade of good, fair, or poor per the Methods Guide for Effectiveness … www.effectivehealthcare.ahrq.gov Published Online: February 23, 2012 12 interest will be given an overall evidence grade … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed

170. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
     January 01, 2020 - Grading the Strength of Evidence (SOE) for Major Compar isons and Outcomes We will grade the strength … Developed to grade the overall strength of a body of evidence, this approach now incorporates five key … We will grade the strength of evidence for all included outcomes. … Definitions of the Grades of Overall Strength of Evidence Grade Definition High We are very confident

171. CER 174 Executive Summary: Imaging for the Pretreatment of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
     April 01, 2016 - The output is a grade for the strength of evidence: high, moderate, low, or insufficient. … This grade is provided separately for each outcome of each comparison of each KQ. … A grade was determined separately for each modality comparison (e.g., CT vs. PET/CT). … If the evidence was sufficient to permit a conclusion, the grade was deemed high, moderate, or low. … The grade was provided by three independent raters, with discrepancies resolved by consensus.

172. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
     September 27, 2012 - the EPC staff believes that such evidence could impact results meaningfully (i.e., alter evidence GRADE … 27, 2012 evidence is outlined in the Methods Guide25 and is based on a system developed by the GRADE … The grade of evidence strength is classified into the following four categories: • High. … The grade rating will be made by independent reviewers, and disagreements will be resolved by consensus

173. Title (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
     March 31, 2010 - Grading the Evidence for Each Key Question At the completion of the review, we will grade the quantity … We will classify evidence pertaining to Key Questions 1- 7 into four basic categories: (1) “high” grade … research is very unlikely to change our confidence in the estimate of the effect); (2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); (3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and (4) “insufficient” grade

174. Increased Risks for Random Errors Are Common in Outcomes Graded as High Certainty of Evidence | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/grant-manuscripts/increased-risks-abstract

175. Evidence-based Practice Center Technical Brief Protocol: Disparities and Barriers for Pediatric Cancer Survivorship Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-cancer-survivorship-protocol.pdf
     June 01, 2020 - OR “youngster“ OR “youngsters“ OR “girl“ OR “girls“ OR “boy“ OR “boys“ OR “elementary school*” OR “grade … OR “youngster“ OR “youngsters“ OR “girl“ OR “girls“ OR “boy“ OR “boys“ OR “elementary school*” OR “grade … OR “youngster“ OR “youngsters“ OR “girl“ OR “girls“ OR “boy“ OR “boys“ OR “elementary school*” OR “grade … youngster OR youngsters OR girl OR girls OR boy OR boys OR elementary school OR elementary schools OR grade … school OR grade schools OR preadolescent OR preadolescents OR preadolescence OR pre adolescent OR pre

176. Medical-Evidence-Communication Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
     July 31, 2012 - The overall strength of evidence grade is made up of judgments about four required domains. … specific determinations of net benefit and also includes applicability in their judgments about evidence grade … Grading the Strength of Evidence for Individual Outcomes We will grade the strength of evidence on … the basis of guidance established for the EPC Program.38,41 Developed to grade the overall strength … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that

177. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
     November 30, 2011 - Key Question We will use the methods outlined in Chapter 10 of the AHRQ Methods Guide 18 to grade … Based on this assessment, the body of evidence will be assigned a strength-of-evidence grade of high … November 30, 2011 9 evidence does not exist, is sparse, or contains irreconcilable inconsistency, a grade

178. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
     October 01, 2006 - mortality rates, over 40 percent within 6 years, occurred mostly in studies of patients with either high-grade … Among the studies, worse kidney function, higher grade stenosis, various markers of cardiac disease, … The other trial included patients with lower grade stenosis (>50 percent) but did not exclude patients … association with either kidney function or diastolic blood pressure. 1 found that patients with higher grade … Baseline Weak • 2 studies found that higher grade stenosis was independently RAS severity associated

179. Hi Les, (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
     January 01, 2009 - have reported LBC has similar sensitivity and specificity to the Pap test for the detection of high-grade … cytology tests being compared might have the same sensitivity when using the total number of true low-grade … and high-grade lesions detected, but one test might detect a higher proportion of high-grade cytological … abnormalities and a lower proportion of low-grade cytological abnormalities than the other test. … The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) Working Group has recently

180. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
     September 01, 2010 - Grading the Evidence for Each Key Question At the completion of our review, we will grade the quantity … We will classify evidence pertaining to Key Questions 1 – 4 into four basic categories: (1) “high” grade … research is very unlikely to change our confidence in the estimate of the effect); (2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); (3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and (4) “insufficient” grade