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121. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
     May 18, 2011 - histology) c) Composite outcome, that is, advanced neoplasia (adenocarcinoma, adenomas with high-grade … Grading the Evidence for Each Key Question We will grade the strength of evidence for primary outcomes … as outlined in the Methods Guide for Effectiveness and Comparative Effectiveness Reviews. 17 The grade … Strength of evidence grades and definitions Grade Definition High High confidence that the evidence

122. depression-pregnancy-postpartum-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
     March 29, 2013 - skills) and educational achievement o Kindergarten readiness o Age at Kindergarten entry o Third grade … testing outcomes o Other standard testing outcomes (Eighth grade, etc) o Intelligence tests (any … edited version of the chapter has also been published in the Journal of Clinical Epidemiology23) to grade … Based on this assessment, the body of evidence will be assigned a strength-of-evidence grade of high … In cases where evidence does not exist, is sparse, or contains irreconcilable inconsistency, a grade

123. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes - We will grade the SOE … based on the guidance established for the EPC program.31 We plan to grade the comparisons of opioids … At the completion of the review, two reviewers will independently grade the SOE.

124. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
     March 14, 2012 - Grading the Evidence for Each Key Question – At the completion of our review, we will grade the strength … Effectiveness and Comparative Effectiveness Reviews.24,25 Both of these evidence grading schemes are based on GRADE … Source: www.effectivehealthcare.ahrq.gov Published Online: March 14, 2012 the estimate); 3) “low” grade … GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.

125. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
     January 01, 2015 - § Hemoglobin A1c (will not evaluate metformin vs. sulfonylureas, evidence is high grade … not evaluate for metformin vs. thiazolidinediones or metformin vs. sulfonylureas; evidence is high grade … be (will not evaluate any of these for metformin vs. sulfonylureas except cancer; evidence is high grade … Additionally, we will grade the strength of evidence for adverse events that are most relevant for a … could change our confidence in the estimate of the effect and may change the estimate); (3) “low” grade

126. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
     February 01, 2008 - to each KQ will be classified into three broad categories: (1) “high”, (2) “moderate”, or (3) “low” grade … Definitions for grading the strength of evidence Grade Definition High There is high confidence that … GRADE handbook for grading quality of evidence and strength of recommendation. … The GRADE Working Group; 2008. 12. Gartlehner G, Hansen RA, Nissman D, Lohr KN, Carey TS. … DVT Deep vein thrombosis EPC Evidence based practice center GCS Graduated compression stocking GRADE

127. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
     February 01, 2008 - to each KQ will be classified into three broad categories: (1) “high”, (2) “moderate”, or (3) “low” grade … Definitions for grading the strength of evidence Grade Definition High There is high confidence that … GRADE handbook for grading quality of evidence and strength of recommendation. … The GRADE Working Group; 2008. 12. Gartlehner G, Hansen RA, Nissman D, Lohr KN, Carey TS. … DVT Deep vein thrombosis EPC Evidence based practice center GCS Graduated compression stocking GRADE

128. Healthcare Delivery of Clinical Preventive Services for People with Disabilities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/people-with-disabilities-protocol.pdf
     January 16, 2024 - A and Grade B recommendations: - Screening (anxiety disorders, breast cancer, cervical cancer, colorectal … Each included preventive service has a Grade A or Grade B recommendation from the United States Preventive … For each population (adults; children and adolescents), screening for depression is Grade B, and screening … for suicide risk is Grade I (insufficient). … Because having a USPSTF Grade A or Grade B recommendation is an inclusion criterion for the systematic

129. Fagerlin-notes-151007 copy-Teresa (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fagerlin-presentation.pdf
     October 08, 2025 - prostate cancer decision  aid  we could   find, all of them are written at least at a ninth grade … Most are written at twelfth grade reading level. … And you al know in here that reading is around an eight grade reading level. … So that means a lot of people are waybelow an eight grade reading level.

130. S123 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s123.pdf
     October 01, 2007 - residence from the nearest radiation center, and local area BCSI rate) and controlling for cancer stage, grade … estimated using ordinary least squares as a function of measured confounding variables (cancer stage, grade … 54.3§ 52.6 53.4 IIa 31.2 32.1 25.6‡ 32.5 30.0§ 31.7 30.7 IIb 15.8 17.2 6.9‡ 15.9 15.7 15.6 15.9 Grade … 70–74, 75–79, 80–84, 85�), tumor sizes (�2, 2–5, and 5� cm), positive lymph node involvement, tumor grade … 70–74, 75–79, 80–84, 85�), tumor sizes (�2, 2–5, and 5� cm), positive lymph node involvement, tumor grade

131. Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
     June 05, 2024 - Based on input from our review’s Key Informants and Technical Expert Panel, we will grade SOE for the … GRADE guidelines: 21 part 1. … GRADE guidelines: 22. … GRADE Working Group. Welcome to the GRADE working group. 2024. … GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach.

132. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
     January 01, 2020 - Grading the Strength of Evidence (SOE) for Major Compar isons and Outcomes We will grade the strength … Developed to grade the overall strength of a body of evidence, this approach now incorporates five key … We will grade the strength of evidence for all included outcomes. … Definitions of the Grades of Overall Strength of Evidence Grade Definition High We are very confident

133. Executive summary_Comparative Effectiveness Review No. 276: Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
     December 01, 2024 - Executive summary_Comparative Effectiveness Review No. 276: Diagnosis and Management of Obsessive Compulsive Disorders in Children Comparative Effectiveness Review Number 276 Diagnosis and Management of Obsessive Compulsive Disorders in Children Executive Summary Main Points • Diagnosis of O…

134. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-2010_research-protocol.pdf
     January 01, 2010 - Studies will be given a quality grade of good, fair, or poor per the Methods Guide for Effectiveness … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed

135. Disposition of Comments for CER 196 The Role of Immunotherapy in the Treatment of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-disposition-comments-immunotherapy-asthma.pdf
     March 23, 2018 - here) Peer Reviewer #2 Introduction Also some background on the GINA classification/severity grade … Anaphylaxis was pre-specified in our protocol as a critical outcome, that is, an outcome for which we would grade … One case series reported of one participant out of 18 presenting “Bronchospasm grade 2”, after receiving … on the 2010 grading system, local reactions with SLIT such as lip pruritus would be considered a grade … We added following text to our limitations section in Discussion: "We tried to grade all adverse events

136. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
     December 06, 2010 - based on the standard methods of the EPCs, which use a revised version of the approach devised by the GRADE … Developed to grade the quality of evidence and the strength of recommendations, this approach incorporates … of evidence and the strength of recommendations I: Critical appraisal of existing approaches: The GRADE

137. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - We relied on our defined approach to grade the strength of evidence. … The Colombel 2010 study was included in our assessment of the evidence grade. … approach to grading the strength of evidence in the methods section, with a definition of what each grade … We used GRADE formula to evaluate the strength of evidence, which included precision. … In summary, the report would greatly improve with standard GRADE style evidence profiles, as finding

138. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
     March 13, 2012 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient … The final choice of which outcomes to grade will be based on rankings of the potential impact of OC

139. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
     April 01, 2011 - The evidence-based tables are appropriate and grade the evidence appropriately. … that the healing rate was only significantly different between PPI treatment groups in patients with grade … Please consider providing additional context as to definition of grade I versus grade C (scales). … , enrolled 4092 patients with endoscopically confirmed EE, 29% of which had moderate-to-severe EE (Grade … the gastric body (n=153) and antrum (n=152), 54% and 55% respectively experienced a reduction in grade

140. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
     January 01, 2023 - There were significantly fewer acute AEs and late AEs Grade ≥2 with IORT. … in clinical trials, for example, postmenopausal age range, estrogen receptor (ER) positive status, grade … patients who participated, for example age <50 years, invasive lobular carcinoma, tumor size 2.1-3 cm, grade